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The vitamin K cycle

Journal of thrombosis and haemostasis, 2005-08, Vol.3 (8), p.1873-1878

STAFFORD, D. W.

2005

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Evaluation of warfarin resistance using transcription activator‐like effector nucleases‐mediated vitamin K epoxide reductase knockout HEK293 cells

Journal of thrombosis and haemostasis, 2013-08, Vol.11 (8), p.1556-1564

2013

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Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH2

Proceedings of the National Academy of Sciences - PNAS, 2006-12, Vol.103 (51), p.19308-19313

2006

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Evidence of clinically significant extravascular stores of factor IX

Journal of thrombosis and haemostasis, 2013-12, Vol.11 (12), p.2176-2178

2013

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Polymorphisms in the VKORC1 gene are strongly associated with warfarin dosage requirements in patients receiving anticoagulation

Journal of medical genetics, 2006-09, Vol.43 (9), p.740-744

2006

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Impact of Social Support on Suicidal Ideation and Attempts Among Gender Minority Adults

International journal of aging & human development, 2023-01, Vol.96 (1), p.117-130

2023

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Functional Study of the Vitamin K Cycle Enzymes in Live Cells

Methods in enzymology, 2017-01, Vol.584, p.349-394

2017

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A Coagulation Factor IX-Deficient Mouse Model for Human Hemophilia B

Blood, 1997-11, Vol.90 (10), p.3962-3966

1997

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Transgene expression levels and kinetics determine risk of humoral immune response modeled in factor IX knockout and missense mutant mice

Gene therapy, 2007-03, Vol.14 (5), p.429-440

2007

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Identification of the gene for vitamin K epoxide reductase

Nature, 2004-02, Vol.427 (6974), p.541-544

2004

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A topological study of the human γ-glutamyl carboxylase

Blood, 2000-08, Vol.96 (3), p.973-978

2000

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Abnormal hemostasis in a knock‐in mouse carrying a variant of factor IX with impaired binding to collagen type IV

Journal of thrombosis and haemostasis, 2009-11, Vol.7 (11), p.1843-1851

2009

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Membrane topology for human vitamin K epoxide reductase

Journal of thrombosis and haemostasis, 2014-01, Vol.12 (1), p.112-114

2014

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Enhanced γ-Carboxylation of Recombinant Factor X Using a Chimeric Construct Containing the Prothrombin Propeptide

Biochemistry (Easton), 2000-11, Vol.39 (46), p.14322-14329

2000

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Complete and sustained phenotypic correction of hemophilia B in mice following hepatic gene transfer of a high‐expressing human factor IX plasmid

Journal of thrombosis and haemostasis, 2003-01, Vol.1 (1), p.103-111

2003

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A Novel Fluorescence Assay To Study Propeptide Interaction with γ-Glutamyl Carboxylase

Biochemistry (Easton), 2001-10, Vol.40 (39), p.11723-11733

2001

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Expression and Characterization of the Naturally Occurring Mutation L394R in Human γ-Glutamyl Carboxylase

The Journal of biological chemistry, 2000-10, Vol.275 (42), p.32572-32577

2000

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Characteristics of recombinant W501S mutated human γ‐glutamyl carboxylase

Journal of thrombosis and haemostasis, 2004-04, Vol.2 (4), p.597-604

2004

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Identification of a gene encoding a typical γ‐carboxyglutamic acid domain in the tunicate Halocynthia roretzi

Journal of thrombosis and haemostasis, 2003-01, Vol.1 (1), p.118-123

2003

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Identification of the Endothelial Cell Binding Site for Factor IX

Proceedings of the National Academy of Sciences - PNAS, 1996-10, Vol.93 (20), p.11068-11073

1996

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Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

Nature medicine, 1999-01, Vol.5 (1), p.64-70

1999

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Localization of the human tissue factor recognition determinant of human factor VIIa

The Journal of biological chemistry, 1991-10, Vol.266 (29), p.19198-19202

1991

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The binding of human factor IX to endothelial cells is mediated by residues 3-11

The Journal of biological chemistry, 1992-10, Vol.267 (29), p.20529-20531

1992

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Identification and Purification to Near Homogeneity of the Vitamin K- Dependent Carboxylase

Proceedings of the National Academy of Sciences - PNAS, 1991-03, Vol.88 (6), p.2236-2240

1991

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Characterization of the purified vitamin K-dependent gamma-glutamyl carboxylase

The Journal of biological chemistry, 1993-04, Vol.268 (12), p.8735-8742

1993

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The vitamin K cycle

Evaluation of warfarin resistance using transcription activator‐like effector nucleases‐mediated vitamin K epoxide reductase knockout HEK293 cells

Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH2

Evidence of clinically significant extravascular stores of factor IX

Polymorphisms in the VKORC1 gene are strongly associated with warfarin dosage requirements in patients receiving anticoagulation

Impact of Social Support on Suicidal Ideation and Attempts Among Gender Minority Adults

Functional Study of the Vitamin K Cycle Enzymes in Live Cells

A Coagulation Factor IX-Deficient Mouse Model for Human Hemophilia B

Transgene expression levels and kinetics determine risk of humoral immune response modeled in factor IX knockout and missense mutant mice

Identification of the gene for vitamin K epoxide reductase

A topological study of the human γ-glutamyl carboxylase

Abnormal hemostasis in a knock‐in mouse carrying a variant of factor IX with impaired binding to collagen type IV

Membrane topology for human vitamin K epoxide reductase

Enhanced γ-Carboxylation of Recombinant Factor X Using a Chimeric Construct Containing the Prothrombin Propeptide

Complete and sustained phenotypic correction of hemophilia B in mice following hepatic gene transfer of a high‐expressing human factor IX plasmid

A Novel Fluorescence Assay To Study Propeptide Interaction with γ-Glutamyl Carboxylase

Expression and Characterization of the Naturally Occurring Mutation L394R in Human γ-Glutamyl Carboxylase

Characteristics of recombinant W501S mutated human γ‐glutamyl carboxylase

Identification of a gene encoding a typical γ‐carboxyglutamic acid domain in the tunicate Halocynthia roretzi

Identification of the Endothelial Cell Binding Site for Factor IX

Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

Localization of the human tissue factor recognition determinant of human factor VIIa

The binding of human factor IX to endothelial cells is mediated by residues 3-11

Identification and Purification to Near Homogeneity of the Vitamin K- Dependent Carboxylase

Characterization of the purified vitamin K-dependent gamma-glutamyl carboxylase

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