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Synthesis and anticonvulsant properties of 1-(amino-N-arylmethanethio)-3-(1-substituted benzyl-2, 3-dioxoindolin-5-yl) urea derivatives

European journal of medicinal chemistry, 2011-06, Vol.46 (6), p.2236-2242

2011

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Anticonvulsant activity of hydrazones, Schiff and Mannich bases of isatin derivatives

European journal of pharmaceutical sciences, 2002-08, Vol.16 (3), p.129-132

2002

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The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models

Epilepsia (Copenhagen), 2008-07, Vol.49 (7), p.1213-1220

2008

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The Structure−Activity Relationship of the 3-Oxy Site in the Anticonvulsant (R)-N-Benzyl 2-Acetamido-3-methoxypropionamide

Journal of medicinal chemistry, 2010-08, Vol.53 (15), p.5716-5726

2010

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Activities of α-asarone in various animal seizure models and in biochemical assays might be essentially accounted for by antioxidant properties

Neuroscience research, 2010-12, Vol.68 (4), p.337-344

2010

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Therapy Discovery for Pharmacoresistant Epilepsy and for Disease‐modifying Therapeutics: Summary of the NIH/NINDS/AES Models II Workshop

Epilepsia, 2003-12, Vol.44 (12), p.1472-1478

2003

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Anticonvulsant properties of various acetylhydrazones, oxamoylhydrazones and semicarbazones derived from aromatic and unsaturated carbonyl compounds

European journal of medicinal chemistry, 2000-02, Vol.35 (2), p.241-248

2000

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Design, synthesis and antiproliferative activity of some 3-benzylidene-2,3-dihydro-1-benzopyran-4-ones which display selective toxicity for malignant cells

European journal of medicinal chemistry, 2008-04, Vol.43 (4), p.839-845

2008

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Synthesis and anticonvulsant activity of 4-bromophenyl substituted aryl semicarbazones

European journal of medicinal chemistry, 2000-10, Vol.35 (10), p.879-886

2000

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Synthesis and structure–activity relationships of potential anticonvulsants based on 2-piperidinecarboxylic acid and related pharmacophores

European journal of medicinal chemistry, 2001-03, Vol.36 (3), p.265-286

2001

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Models for Epilepsy and Epileptogenesis: Report from the NIH Workshop, Bethesda, Maryland

Epilepsia (Copenhagen), 2002-11, Vol.43 (11), p.1410-1420

2002

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Design & synthesis of N′-[substituted] pyridine-4-carbohydrazides as potential anticonvulsant agents

European journal of medicinal chemistry, 2011-02, Vol.46 (2), p.509-518

2011

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A new class of anticonvulsants possessing 6 Hz activity: 3,4-Dialkyloxy thiophene bishydrazones

European journal of medicinal chemistry, 2009-11, Vol.44 (11), p.4376-4384

2009

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Design, synthesis and potential 6 Hz psychomotor seizure test activity of some novel 2-(substituted)-3-{[substituted]amino}quinazolin-4(3 H)-one

European journal of medicinal chemistry, 2011-04, Vol.46 (4), p.1006-1018

2011

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Synthesis and anticonvulsant activities of N-benzyl (2 R)-2-acetamido-3-oxysubstituted propionamide derivatives

Bioorganic & medicinal chemistry, 2008-10, Vol.16 (19), p.8968-8975

2008

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Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives

Bioorganic & medicinal chemistry, 2010-04, Vol.18 (8), p.2902-2911

2010

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Psychomotor Seizure Test, Neurotoxicity and in vitro Neuroprotection Assay of some Semicarbazone Analogues

Central nervous system agents in medicinal chemistry, 2013-06, Vol.13 (2), p.141-147

2013

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Derivatives of aryl amines containing the cytotoxic 1,4-dioxo-2-butenyl pharmacophore

Bioorganic & medicinal chemistry letters, 2010-03, Vol.20 (5), p.1510-1515

2010

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Design, synthesis and anticonvulsant evaluation of novel N-(4-substituted phenyl)-2-[4-(substituted) benzylidene]-hydrazinecarbothio amides

European journal of medicinal chemistry, 2012, Vol.47 (1), p.153-166

2012

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Modulation of sodium channel inactivation gating by a novel lactam: implications for seizure suppression in chronic limbic epilepsy

The Journal of pharmacology and experimental therapeutics, 2009-01, Vol.328 (1), p.201-212

2009

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Anticonvulsant activity of Schiff bases of isatin derivatives

Acta pharmaceutica (Zagreb, Croatia), 2004-03, Vol.54 (1), p.49

2004

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Synthesis and anticonvulsant activity of 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues

Journal of enzyme inhibition and medicinal chemistry, 2013-06, Vol.28 (3), p.644-650

2013

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Correlations between Cytotoxicity and Topography of Some 2-Arylidenebenzocycloalkanones Determined by X-ray Crystallography

Journal of medicinal chemistry, 2002-07, Vol.45 (14), p.3103-3111

2002

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Synthesis and Anticonvulsant Activities of N-Benzyl-2-acetamidopropionamide Derivatives

Journal of medicinal chemistry, 1996-04, Vol.39 (9), p.1907-1916

1996

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A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage

Epilepsia (Copenhagen), 2012-01, Vol.53 (1), p.134-146

2012

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Synthesis and anticonvulsant properties of 1-(amino-N-arylmethanethio)-3-(1-substituted benzyl-2, 3-dioxoindolin-5-yl) urea derivatives

Anticonvulsant activity of hydrazones, Schiff and Mannich bases of isatin derivatives

The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models

The Structure−Activity Relationship of the 3-Oxy Site in the Anticonvulsant (R)-N-Benzyl 2-Acetamido-3-methoxypropionamide

Activities of α-asarone in various animal seizure models and in biochemical assays might be essentially accounted for by antioxidant properties

Therapy Discovery for Pharmacoresistant Epilepsy and for Disease‐modifying Therapeutics: Summary of the NIH/NINDS/AES Models II Workshop

Anticonvulsant properties of various acetylhydrazones, oxamoylhydrazones and semicarbazones derived from aromatic and unsaturated carbonyl compounds

Design, synthesis and antiproliferative activity of some 3-benzylidene-2,3-dihydro-1-benzopyran-4-ones which display selective toxicity for malignant cells

Synthesis and anticonvulsant activity of 4-bromophenyl substituted aryl semicarbazones

Synthesis and structure–activity relationships of potential anticonvulsants based on 2-piperidinecarboxylic acid and related pharmacophores

Models for Epilepsy and Epileptogenesis: Report from the NIH Workshop, Bethesda, Maryland

Design & synthesis of N′-[substituted] pyridine-4-carbohydrazides as potential anticonvulsant agents

A new class of anticonvulsants possessing 6 Hz activity: 3,4-Dialkyloxy thiophene bishydrazones

Design, synthesis and potential 6 Hz psychomotor seizure test activity of some novel 2-(substituted)-3-{[substituted]amino}quinazolin-4(3 H)-one

Synthesis and anticonvulsant activities of N-benzyl (2 R)-2-acetamido-3-oxysubstituted propionamide derivatives

Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives

Psychomotor Seizure Test, Neurotoxicity and in vitro Neuroprotection Assay of some Semicarbazone Analogues

Derivatives of aryl amines containing the cytotoxic 1,4-dioxo-2-butenyl pharmacophore

Design, synthesis and anticonvulsant evaluation of novel N-(4-substituted phenyl)-2-[4-(substituted) benzylidene]-hydrazinecarbothio amides

Modulation of sodium channel inactivation gating by a novel lactam: implications for seizure suppression in chronic limbic epilepsy

Anticonvulsant activity of Schiff bases of isatin derivatives

Synthesis and anticonvulsant activity of 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues

Correlations between Cytotoxicity and Topography of Some 2-Arylidenebenzocycloalkanones Determined by X-ray Crystallography

Synthesis and Anticonvulsant Activities of N-Benzyl-2-acetamidopropionamide Derivatives

A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage

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