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Quantitation of a Ketone Enolization and a Vinyl Sulfonate Stereoisomer Formation Using Inline IR Spectroscopy and Modeling

Organic process research & development, 2019-05, Vol.23 (5), p.945-951

2019

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Umpolung Flow Chemistry for the Synthesis of a 3‑Oxo‑3H‑spiro[benzofuran-2,4′-piperidine] Building Block

Journal of organic chemistry, 2024-06, Vol.89 (11), p.7618-7629

2024

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Manufacture of the PI3K β‑Sparing Inhibitor Taselisib. Part 1: Early-Stage Development Routes to the Bromobenzoxazepine Core

Organic process research & development, 2019-05, Vol.23 (5), p.775-782

2019

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Manufacture of the PI3K β‑Sparing Inhibitor Taselisib. Part 2: Development of a Highly Efficient and Regioselective Late-Stage Process

Organic process research & development, 2019-05, Vol.23 (5), p.783-793

2019

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Streamlined Synthesis of SHP2 Inhibitor GDC-1971 Enhanced by a Telescoped Schotten-Baumann S N Ar and Reactive Crystallization Cascade

Organic process research & development, 2024-07, Vol.28 (7), p.2862-2874

2024

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Stereoselective Synthesis of the IDO Inhibitor Navoximod

Journal of organic chemistry, 2022-04, Vol.87 (7), p.4955-4960

2022

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Study of a Competing Hydrodefluorination Reaction During the Directed ortho-Lithiation/Borylation of 2‑Fluorobenzaldehyde

Organometallics, 2019-01, Vol.38 (1), p.119-128

2019

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Practical Early Development Synthesis of Nav1.7 Inhibitor GDC-0310

Synthesis (Stuttgart), 2020-11, Vol.52 (22), p.3406-3414

2020

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Identification of an acetonitrile addition impurity formed during peptide disulfide bond reduction using dithiothreitol and Tris(2-carboxyethyl)phosphine

Journal of pharmaceutical and biomedical analysis, 2019-09, Vol.174, p.518-524

2019

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Guided optimization of a crystallization-induced diastereomer transformation to access a key navoximod intermediate

Reaction chemistry & engineering, 2023-05, Vol.8 (6), p.1294-1299

2023

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Umpolung Flow Chemistry for the Synthesis of a 3-Oxo-3 H -spiro[benzofuran-2,4'-piperidine] Building Block

Journal of organic chemistry, 2024-05

2024

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Access to Saturated Fused Pyrimidine Derivatives via a Flexible N-Vinyl Tertiary Enamide Synthesis

Synlett, 2011-10, Vol.2011 (16), p.2387-2391

2011

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Synthesis of Akt Inhibitor Ipatasertib. Part 2. Total Synthesis and First Kilogram Scale-up

Organic process research & development, 2014-12, Vol.18 (12), p.1652-1666

2014

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Pyrimidoaminotropanes as Potent, Selective, and Efficacious Small Molecule Kinase Inhibitors of the Mammalian Target of Rapamycin (mTOR)

Journal of medicinal chemistry, 2013-04, Vol.56 (7), p.3090-3101

2013

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ChemInform Abstract: Access to Saturated Fused Pyrimidine Derivatives via a Flexible N-Vinyl Tertiary Enamide Synthesis

ChemInform, 2012-01, Vol.43 (3), p.no-no

2012

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Quenching Circuit Discriminator Architecture Impact on a Sub-10 ps FWHM Single-Photon Timing Resolution SPAD

Instruments (Basel), 2023-04, Vol.7 (2), p.16

2023

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Validity, reliability and responsiveness of a French translation of the Western Ontario Osteoarthritis of the Shoulder index (WOOS)

Orthopaedics & traumatology, surgery & research, 2024-09, Vol.110 (5), p.103912, Article 103912

2024

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The Canadian Pediatric Cardiology Research Network: A Model National Data-Sharing Organization to Facilitate the Study of Pediatric Heart Diseases

CJC open (Online), 2021-04, Vol.3 (4), p.510-515

2021

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Suture bridge transosseous equivalent repair is stronger than transosseous tied braided-tape

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2017-11, Vol.22 (6), p.1120-1125

2017

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Methods to monitor monocytes-mediated amyloid-beta uptake and phagocytosis in the context of adjuvanted immunotherapies

Journal of immunological methods, 2015-09, Vol.424, p.64-79

2015

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Daytime depth and thermal habitat of two sympatric krill species in response to surface salinity variability in the Gulf of St Lawrence, eastern Canada

ICES journal of marine science, 2014-01, Vol.71 (2), p.272-281

2014

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Validité, fiabilité et réactivité de la traduction française du Western Ontario Osteoarthritis of the shoulder index (WOOS)

Revue de chirurgie orthopédique et traumatologique, 2024-09, Vol.110 (5), p.739-745

2024

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12459 Exceptional Response To A Single Dose Of Pembrolizumab As Salvage Therapy In A Patient With Metastatic Adrenocortical Carcinoma (ACC)

Journal of the Endocrine Society, 2024-10, Vol.8 (Supplement_1)

2024

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Induction therapy with cetuximab plus docetaxel, cisplatin, and 5‐fluorouracil (ETPF) in patients with resectable nonmetastatic stage III or IV squamous cell carcinoma of the oropharynx. A GERCOR phase II ECHO‐07 study

Cancer medicine (Malden, MA), 2015-05, Vol.4 (5), p.721-731

2015

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7537 Composite Pheochromocytoma-Ganglioneuroma Secreting Vasoactive Intestinal Peptide: A Case Report

Journal of the Endocrine Society, 2024-10, Vol.8 (Supplement_1)

2024

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Quantitation of a Ketone Enolization and a Vinyl Sulfonate Stereoisomer Formation Using Inline IR Spectroscopy and Modeling

Umpolung Flow Chemistry for the Synthesis of a 3‑Oxo‑3H‑spiro[benzofuran-2,4′-piperidine] Building Block

Manufacture of the PI3K β‑Sparing Inhibitor Taselisib. Part 1: Early-Stage Development Routes to the Bromobenzoxazepine Core

Manufacture of the PI3K β‑Sparing Inhibitor Taselisib. Part 2: Development of a Highly Efficient and Regioselective Late-Stage Process

Streamlined Synthesis of SHP2 Inhibitor GDC-1971 Enhanced by a Telescoped Schotten-Baumann S N Ar and Reactive Crystallization Cascade

Stereoselective Synthesis of the IDO Inhibitor Navoximod

Study of a Competing Hydrodefluorination Reaction During the Directed ortho-Lithiation/Borylation of 2‑Fluorobenzaldehyde

Practical Early Development Synthesis of Nav1.7 Inhibitor GDC-0310

Identification of an acetonitrile addition impurity formed during peptide disulfide bond reduction using dithiothreitol and Tris(2-carboxyethyl)phosphine

Guided optimization of a crystallization-induced diastereomer transformation to access a key navoximod intermediate

Umpolung Flow Chemistry for the Synthesis of a 3-Oxo-3 H -spiro[benzofuran-2,4'-piperidine] Building Block

Access to Saturated Fused Pyrimidine Derivatives via a Flexible N-Vinyl Tertiary Enamide Synthesis

Synthesis of Akt Inhibitor Ipatasertib. Part 2. Total Synthesis and First Kilogram Scale-up

Pyrimidoaminotropanes as Potent, Selective, and Efficacious Small Molecule Kinase Inhibitors of the Mammalian Target of Rapamycin (mTOR)

ChemInform Abstract: Access to Saturated Fused Pyrimidine Derivatives via a Flexible N-Vinyl Tertiary Enamide Synthesis

Quenching Circuit Discriminator Architecture Impact on a Sub-10 ps FWHM Single-Photon Timing Resolution SPAD

Validity, reliability and responsiveness of a French translation of the Western Ontario Osteoarthritis of the Shoulder index (WOOS)

The Canadian Pediatric Cardiology Research Network: A Model National Data-Sharing Organization to Facilitate the Study of Pediatric Heart Diseases

Suture bridge transosseous equivalent repair is stronger than transosseous tied braided-tape

Methods to monitor monocytes-mediated amyloid-beta uptake and phagocytosis in the context of adjuvanted immunotherapies

Daytime depth and thermal habitat of two sympatric krill species in response to surface salinity variability in the Gulf of St Lawrence, eastern Canada

Validité, fiabilité et réactivité de la traduction française du Western Ontario Osteoarthritis of the shoulder index (WOOS)

12459 Exceptional Response To A Single Dose Of Pembrolizumab As Salvage Therapy In A Patient With Metastatic Adrenocortical Carcinoma (ACC)

Induction therapy with cetuximab plus docetaxel, cisplatin, and 5‐fluorouracil (ETPF) in patients with resectable nonmetastatic stage III or IV squamous cell carcinoma of the oropharynx. A GERCOR phase II ECHO‐07 study

7537 Composite Pheochromocytoma-Ganglioneuroma Secreting Vasoactive Intestinal Peptide: A Case Report

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