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AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species

Cell reports (Cambridge), 2017-10, Vol.21 (1), p.1-9

2017

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AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (29), p.12017-12022

2007

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Reduced exercise capacity for muscle mass in adolescents living with obesity

Pediatric pulmonology, 2024-05, Vol.59 (5), p.1227-1235

2024

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Peroxisome proliferator‐activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging

Aging cell, 2019-10, Vol.18 (5), p.e12993-n/a

2019

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A salicylic acid derivative extends the lifespan of Caenorhabditis elegans by activating autophagy and the mitochondrial unfolded protein response

Aging cell, 2018-12, Vol.17 (6), p.e12830-n/a

2018

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A survey of stakeholders' perceived importance of health indicators and subgroup analyses to inform the Canadian clinical practice guideline for managing paediatric obesity

Pediatric obesity, 2022-11, Vol.17 (11), p.e12949-n/a

2022

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Canadian Cardiovascular Society Position Statement on Familial Hypercholesterolemia

Canadian journal of cardiology, 2014-12, Vol.30 (12), p.1471-1481

2014

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Alterations in cellular energy metabolism associated with the antiproliferative effects of the ATM inhibitor KU-55933 and with metformin

PloS one, 2012-11, Vol.7 (11), p.e49513-e49513

2012

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Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

Cancer cell, 2006-06, Vol.9 (6), p.425-434

2006

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mTOR coordinates protein synthesis, mitochondrial activity and proliferation

Cell cycle (Georgetown, Tex.), 2015, Vol.14 (4), p.473-480

2015

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Metabolic Fitness and Plasticity in Cancer Progression

Trends in Cancer, 2020-01, Vol.6 (1), p.49-61

2020

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mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1

Molecular cell, 2017-09, Vol.67 (6), p.922-935.e5

2017

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PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer

Cell metabolism, 2015-10, Vol.22 (4), p.577-589

2015

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Metformin directly acts on mitochondria to alter cellular bioenergetics

Cancer & metabolism, 2014-08, Vol.2 (1), p.12-12, Article 12

2014

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Estrogen-related receptors are targetable ROS sensors

Genes & development, 2020-04, Vol.34 (7-8), p.544-559

2020

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mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation

Cell metabolism, 2013-11, Vol.18 (5), p.698-711

2013

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Metabolic Profiles Associated With Metformin Efficacy in Cancer

Frontiers in endocrinology (Lausanne), 2018-08, Vol.9, p.372-372

2018

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Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis

Cell reports (Cambridge), 2019-06, Vol.27 (13), p.3902-3915.e6

2019

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Serine deprivation enhances antineoplastic activity of biguanides

Cancer research (Chicago, Ill.), 2014-12, Vol.74 (24), p.7521-7533

2014

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Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2

Nature communications, 2019-09, Vol.10 (1), p.3960-13, Article 3960

2019

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Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin

Neoplasia (New York, N.Y.), 2021-04, Vol.23 (4), p.391-399

2021

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Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators

Cell, 2006-10, Vol.127 (2), p.397-408

2006

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Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation

Cell metabolism, 2006-05, Vol.3 (5), p.333-341

2006

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Modulation of Leptin Resistance by Protein Tyrosine Phosphatases

Cell metabolism, 2012-03, Vol.15 (3), p.292-297

2012

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AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

Reduced exercise capacity for muscle mass in adolescents living with obesity

Peroxisome proliferator‐activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging

A salicylic acid derivative extends the lifespan of Caenorhabditis elegans by activating autophagy and the mitochondrial unfolded protein response

Effectiveness of pharmacological interventions for managing obesity in children and adolescents: A systematic review and meta‐analysis framed using minimal important difference estimates based on GRADE guidance to inform a clinical practice guideline

A survey of stakeholders' perceived importance of health indicators and subgroup analyses to inform the Canadian clinical practice guideline for managing paediatric obesity

Canadian Cardiovascular Society Position Statement on Familial Hypercholesterolemia

Alterations in cellular energy metabolism associated with the antiproliferative effects of the ATM inhibitor KU-55933 and with metformin

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

mTOR coordinates protein synthesis, mitochondrial activity and proliferation

Metabolic Fitness and Plasticity in Cancer Progression

mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1

PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer

Metformin directly acts on mitochondria to alter cellular bioenergetics

Estrogen-related receptors are targetable ROS sensors

mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation

Metabolic Profiles Associated With Metformin Efficacy in Cancer

Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis

Serine deprivation enhances antineoplastic activity of biguanides

Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2

Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin

Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators

Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation

Modulation of Leptin Resistance by Protein Tyrosine Phosphatases

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