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Combined mTORC1/mTORC2 inhibition blocks growth and induces catastrophic macropinocytosis in cancer cells

Proceedings of the National Academy of Sciences - PNAS, 2019-12, Vol.116 (49), p.24583-24592

2019

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The mechanistic basis of arsenicosis: Pathogenesis of skin cancer

Cancer letters, 2014-11, Vol.354 (2), p.211-219

2014

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GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis

Oncotarget, 2014-12, Vol.5 (23), p.12151-12165

2014

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Cutaneous exposure to lewisite causes acute kidney injury by invoking DNA damage and autophagic response

American journal of physiology. Renal physiology, 2018-06, Vol.314 (6), p.F1166-F1176

2018

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Defining cutaneous molecular pathobiology of arsenicals using phenylarsine oxide as a prototype

Scientific reports, 2016-10, Vol.6 (1), p.34865, Article 34865

2016

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Multi-walled carbon nanotubes induce oxidative stress and apoptosis in human lung cancer cell line-A549

Nanotoxicology, 2011-06, Vol.5 (2), p.195-207

2011

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Biological and environmental hazards associated with exposure to chemical warfare agents: arsenicals

Annals of the New York Academy of Sciences, 2016-08, Vol.1378 (1), p.143-157

2016

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Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome

Oncotarget, 2015-11, Vol.6 (34), p.36789-36814

2015

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Microneedle-mediated transdermal delivery of N-acetyl cysteine as a potential antidote for lewisite injury

International journal of pharmaceutics, 2023-11, Vol.647, p.123547-123547, Article 123547

2023

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Role of hair follicles in the pathogenesis of arsenical‐induced cutaneous damage

Annals of the New York Academy of Sciences, 2022-09, Vol.1515 (1), p.168-183

2022

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Combined inhibition of BET bromodomain and mTORC1/2 provides therapeutic advantage for rhabdomyosarcoma by switching cell death mechanism

Molecular carcinogenesis, 2022-08, Vol.61 (8), p.737-751

2022

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Molecular Mechanism Underlying Pathogenesis of Lewisite-Induced Cutaneous Blistering and Inflammation: Chemical Chaperones as Potential Novel Antidotes

The American journal of pathology, 2016-10, Vol.186 (10), p.2637-2649

2016

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Cutaneous Arsenical Exposure Induces Distinct Metabolic Transcriptional Alterations of Kidney Cells

The Journal of pharmacology and experimental therapeutics, 2024-02, Vol.388 (2), p.605-612

2024

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Development of BRD4 inhibitors as anti-inflammatory agents and antidotes for arsenicals

Bioorganic & medicinal chemistry letters, 2022-05, Vol.64, p.128696-128696, Article 128696

2022

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Arsenic-induced cutaneous hyperplastic lesions are associated with the dysregulation of Yap, a Hippo signaling-related protein

Biochemical and biophysical research communications, 2013-09, Vol.438 (4), p.607-612

2013

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Topical delivery of nordihydroguaretic acid for attenuating cutaneous damage caused by arsenicals

Journal of drug delivery science and technology, 2020-08, Vol.58, p.101773, Article 101773

2020

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Protective role of HO‐1 against acute kidney injury caused by cutaneous exposure to arsenicals

Annals of the New York Academy of Sciences, 2020-11, Vol.1480 (1), p.155-169

2020

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ATF4 regulates arsenic trioxide-mediated NADPH oxidase, ER-mitochondrial crosstalk and apoptosis

Archives of biochemistry and biophysics, 2016-11, Vol.609, p.39-50

2016

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Development of 4-phenylbutyric acid microsponge gel formulations for the treatment of lewisite-mediated skin injury

Drug delivery and translational research, 2024-05

2024

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Rapamycin targeting mTOR and hedgehog signaling pathways blocks human rhabdomyosarcoma growth in xenograft murine model

Biochemical and biophysical research communications, 2013-06, Vol.435 (4), p.557-561

2013

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Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model

Toxicology and applied pharmacology, 2013-01, Vol.266 (2), p.233-244

2013

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Distal airway microbiome is associated with immunoregulatory myeloid cell responses in lung transplant recipients

The Journal of heart and lung transplantation, 2018-02, Vol.37 (2), p.206-216

2018

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Activating transcription factor 4 underlies the pathogenesis of arsenic trioxide-mediated impairment of macrophage innate immune functions

Toxicology and applied pharmacology, 2016-10, Vol.308, p.46-58

2016

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Molecular Mechanism Underlying Pathogenesis of Lewisite-Induced Cutaneous Blistering and Inflammation

The American journal of pathology, 2016-10, Vol.186 (10), p.2637-2649

2016

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Erb-041, an Estrogen Receptor-β Agonist, Inhibits Skin Photocarcinogenesis in SKH-1 Hairless Mice by Downregulating the WNT Signaling Pathway

Cancer prevention research (Philadelphia, Pa.), 2014-02, Vol.7 (2), p.186-198

2014

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Combined mTORC1/mTORC2 inhibition blocks growth and induces catastrophic macropinocytosis in cancer cells

The mechanistic basis of arsenicosis: Pathogenesis of skin cancer

GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis

Cutaneous exposure to lewisite causes acute kidney injury by invoking DNA damage and autophagic response

Defining cutaneous molecular pathobiology of arsenicals using phenylarsine oxide as a prototype

Multi-walled carbon nanotubes induce oxidative stress and apoptosis in human lung cancer cell line-A549

Biological and environmental hazards associated with exposure to chemical warfare agents: arsenicals

Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome

Microneedle-mediated transdermal delivery of N-acetyl cysteine as a potential antidote for lewisite injury

Role of hair follicles in the pathogenesis of arsenical‐induced cutaneous damage

Combined inhibition of BET bromodomain and mTORC1/2 provides therapeutic advantage for rhabdomyosarcoma by switching cell death mechanism

Molecular Mechanism Underlying Pathogenesis of Lewisite-Induced Cutaneous Blistering and Inflammation: Chemical Chaperones as Potential Novel Antidotes

Cutaneous Arsenical Exposure Induces Distinct Metabolic Transcriptional Alterations of Kidney Cells

Development of BRD4 inhibitors as anti-inflammatory agents and antidotes for arsenicals

Arsenic-induced cutaneous hyperplastic lesions are associated with the dysregulation of Yap, a Hippo signaling-related protein

Topical delivery of nordihydroguaretic acid for attenuating cutaneous damage caused by arsenicals

Protective role of HO‐1 against acute kidney injury caused by cutaneous exposure to arsenicals

ATF4 regulates arsenic trioxide-mediated NADPH oxidase, ER-mitochondrial crosstalk and apoptosis

Development of 4-phenylbutyric acid microsponge gel formulations for the treatment of lewisite-mediated skin injury

Rapamycin targeting mTOR and hedgehog signaling pathways blocks human rhabdomyosarcoma growth in xenograft murine model

Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model

Distal airway microbiome is associated with immunoregulatory myeloid cell responses in lung transplant recipients

Activating transcription factor 4 underlies the pathogenesis of arsenic trioxide-mediated impairment of macrophage innate immune functions

Molecular Mechanism Underlying Pathogenesis of Lewisite-Induced Cutaneous Blistering and Inflammation

Erb-041, an Estrogen Receptor-β Agonist, Inhibits Skin Photocarcinogenesis in SKH-1 Hairless Mice by Downregulating the WNT Signaling Pathway

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