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Mechanics and pharmacology of substrate selection and transport by eukaryotic ABC exporters

Nature structural & molecular biology, 2019-09, Vol.26 (9), p.792

2019

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The evolution of a counter-defense mechanism in a virus constrains its host range

eLife, 2022-08, Vol.11

2022

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Evolutionary history of ATP‐binding cassette proteins

FEBS letters, 2020-12, Vol.594 (23), p.3882-3897

Srikant, Sriram

2020

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D-helix influences dimerization of the ATP-binding cassette (ABC) transporter associated with antigen processing 1 (TAP1) nucleotide-binding domain

PloS one, 2017-05, Vol.12 (5), p.e0178238-e0178238

2017

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Extending the reach of homology by using successive computational filters to find yeast pheromone genes

Current biology, 2023-10, Vol.33 (19), p.4098-4110.e3

2023

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Selecting for Altered Substrate Specificity Reveals the Evolutionary Flexibilityof ATP-Binding Cassette Transporters

Current biology, 2020-03, Vol.30 (9), p.1689-1702.e6

2020

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Selecting for Altered Substrate Specificity Reveals the Evolutionary Flexibility of ATP-Binding Cassette Transporters

Current biology, 2020-05, Vol.30 (9), p.1689-1702.e6

2020

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Direct activation of a bacterial innate immune system by a viral capsid protein

Nature (London), 2022-12, Vol.612 (7938), p.132-140

2022

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D-helix influences dimerization of the ATP-binding cassette nucleotide-binding domain

PloS one, 2017-05, Vol.12 (5), p.e0178238

2017

Volltextzugriff (PDF)

D-helix influences dimerization of the ATP-binding cassette

PloS one, 2017-05, Vol.12 (5), p.e0178238

2017

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A phage-encoded RNA-binding protein inhibits the antiviral activity of a toxin-antitoxin system

Nucleic acids research, 2024-02, Vol.52 (3), p.1298

2024

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Natural Transformation Protein ComFA Exhibits Single-Stranded DNA Translocase Activity

Journal of bacteriology, 2022-03, Vol.204 (3), p.e0051821-e0051821

2022

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The DarTG toxin-antitoxin system provides phage defence by ADP-ribosylating viral DNA

Nature microbiology, 2022-07, Vol.7 (7), p.1028

2022

Volltextzugriff (PDF)

Evolution of Substrate Selectivity in Atp Binding Cassette Exporters

Srikant, Sriram

2019

Volltextzugriff (PDF)

Behaviour of hydrogen bonding and structure of poly(acrylic acid) in water-ethanol solution investigated by explicit ion molecular dynamics simulations

Molecular simulation, 2013-02, Vol.39 (2), p.145-153

2013

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Behaviour of hydrogen bonding and structure of poly(acrylic acid) in wateraethanol solution investigated by explicit ion molecular dynamics simulations

Molecular simulation, 2013-01, Vol.39 (2), p.145-153

2013

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Energy-Based Pharmacophore and Three-Dimensional Quantitative Structure–Activity Relationship (3D-QSAR) Modeling Combined with Virtual Screening To Identify Novel Small-Molecule Inhibitors of Silent Mating-Type Information Regulation 2 Homologue 1 (SIRT1)

Journal of chemical information and modeling, 2016-01, Vol.56 (1), p.173-187

2016

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α-Sulfonamidophosphonates as new anti-mycobacterial chemotypes: Design, development of synthetic methodology, and biological evaluation

Bioorganic chemistry, 2019-02, Vol.82, p.246-252

2019

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rGO/ReO3 nano composite modified electrode for the ultra-sensitive determination of dopamine and uric acid

Biosensors and bioelectronics. X, 2022-09, Vol.11, p.100156, Article 100156

2022

Volltextzugriff (PDF)

Targeting NAMPT for Therapeutic Intervention in Cancer and Inflammation: Structure-Based Drug Design and Biological Screening

Chemical biology & drug design, 2015-10, Vol.86 (4), p.881-894

2015

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Structure-based drug design of small molecule SIRT1 modulators to treat cancer and metabolic disorders

Journal of molecular graphics & modelling, 2014-07, Vol.52, p.46-56

2014

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Cathepsin D inhibitors as potential therapeutics for breast cancer treatment: Molecular docking and bioevaluation against triple-negative and triple-positive breast cancers

Molecular diversity, 2016-05, Vol.20 (2), p.521-535

2016

Volltextzugriff (PDF)

Abstract B172: RP10107, a novel and potent glutaminase inhibitor, potentiates taxol activity in breast cancer cell lines

Molecular cancer therapeutics, 2015-12, Vol.14 (12_Supplement_2), p.B172-B172

2015

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A Novel, Potent, Small Molecule AKT Inhibitor Exhibits Efficacy against Lung Cancer Cells In Vitro

Cancer Research and Treatment, 2015, 47(4), , pp.913-920

2015

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A Novel, Potent, Small Molecule AKT Inhibitor Exhibits Efficacy against Lung Cancer Cells In Vitro

Cancer research and treatment, 2015-10, p.913-920

2015

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Mechanics and pharmacology of substrate selection and transport by eukaryotic ABC exporters

The evolution of a counter-defense mechanism in a virus constrains its host range

Evolutionary history of ATP‐binding cassette proteins

D-helix influences dimerization of the ATP-binding cassette (ABC) transporter associated with antigen processing 1 (TAP1) nucleotide-binding domain

Extending the reach of homology by using successive computational filters to find yeast pheromone genes

Selecting for Altered Substrate Specificity Reveals the Evolutionary Flexibilityof ATP-Binding Cassette Transporters

Selecting for Altered Substrate Specificity Reveals the Evolutionary Flexibility of ATP-Binding Cassette Transporters

Direct activation of a bacterial innate immune system by a viral capsid protein

D-helix influences dimerization of the ATP-binding cassette nucleotide-binding domain

D-helix influences dimerization of the ATP-binding cassette

A phage-encoded RNA-binding protein inhibits the antiviral activity of a toxin-antitoxin system

Natural Transformation Protein ComFA Exhibits Single-Stranded DNA Translocase Activity

The DarTG toxin-antitoxin system provides phage defence by ADP-ribosylating viral DNA

Evolution of Substrate Selectivity in Atp Binding Cassette Exporters

Behaviour of hydrogen bonding and structure of poly(acrylic acid) in water-ethanol solution investigated by explicit ion molecular dynamics simulations

Behaviour of hydrogen bonding and structure of poly(acrylic acid) in wateraethanol solution investigated by explicit ion molecular dynamics simulations

Energy-Based Pharmacophore and Three-Dimensional Quantitative Structure–Activity Relationship (3D-QSAR) Modeling Combined with Virtual Screening To Identify Novel Small-Molecule Inhibitors of Silent Mating-Type Information Regulation 2 Homologue 1 (SIRT1)

α-Sulfonamidophosphonates as new anti-mycobacterial chemotypes: Design, development of synthetic methodology, and biological evaluation

rGO/ReO3 nano composite modified electrode for the ultra-sensitive determination of dopamine and uric acid

Targeting NAMPT for Therapeutic Intervention in Cancer and Inflammation: Structure-Based Drug Design and Biological Screening

Structure-based drug design of small molecule SIRT1 modulators to treat cancer and metabolic disorders

Cathepsin D inhibitors as potential therapeutics for breast cancer treatment: Molecular docking and bioevaluation against triple-negative and triple-positive breast cancers

Abstract B172: RP10107, a novel and potent glutaminase inhibitor, potentiates taxol activity in breast cancer cell lines

A Novel, Potent, Small Molecule AKT Inhibitor Exhibits Efficacy against Lung Cancer Cells In Vitro

A Novel, Potent, Small Molecule AKT Inhibitor Exhibits Efficacy against Lung Cancer Cells In Vitro

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