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Analysis and functional relevance of the chaperone TRAP-1 interactome in the metabolic regulation and mitochondrial integrity of cancer cells

Scientific reports, 2023-05, Vol.13 (1), p.7584-7584, Article 7584

2023

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Hsp90 chaperone facilitates E2F1/2-dependent gene transcription in human breast cancer cells

European journal of cell biology, 2021-01, Vol.100 (1), p.151148-151148, Article 151148

2021

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Heat shock transcription factor HSF2 modulates the autophagy response through the BTG2-SOD2 axis

Biochemical and biophysical research communications, 2022-04, Vol.600, p.44-50

2022

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Hsp90 isoforms: functions, expression and clinical importance

FEBS Letters, 2004-03, Vol.562 (1-3), p.11-15

2004

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The mitochondrial chaperone TRAP-1 regulates the glutamine metabolism in tumor cells

Mitochondrion, 2023-03, Vol.69, p.159-170

2023

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Hsp90 regulates HDAC3-dependent gene transcription while HDAC3 regulates the functions of Hsp90

Cellular signalling, 2020-12, Vol.76, p.109801-109801, Article 109801

2020

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The conformation-specific Hsp90 inhibition interferes with the oncogenic RAF kinase adaptation and triggers premature cellular senescence, hence, acts as a tumor suppressor mechanism

Biochimica et biophysica acta. Molecular cell research, 2021-03, Vol.1868 (3), p.118943-118943, Article 118943

2021

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Hsp90 facilitates acquired drug resistance of tumor cells through cholesterol modulation however independent of tumor progression

Biochimica et biophysica acta. Molecular cell research, 2020-08, Vol.1867 (8), p.118728-118728, Article 118728

2020

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Corrigendum to “Hsp90 chaperone facilitates E2F1/2-dependent gene transcription in human breast cancer cells” [Eur. J. Cell Biol. 100 (2021) 151148]

European journal of cell biology, 2021-04, Vol.100 (3), p.151157, Article 151157

2021

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Compromising the constitutive p16INK4a expression sensitizes human neuroblastoma cells to Hsp90 inhibition and promotes premature senescence

Journal of cellular biochemistry, 2020-04, Vol.121 (4), p.2770-2781

2020

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Altered molecular pathways decides the treatment outcome of Hsp90 inhibitors against breast cancer cells

Toxicology in vitro, 2020-06, Vol.65, p.104828, Article 104828

2020

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Mitochondrial chaperone, TRAP1 modulates mitochondrial dynamics and promotes tumor metastasis

Mitochondrion, 2020-09, Vol.54, p.92-101

2020

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The matrix metalloproteinase 7 (MMP7) links Hsp90 chaperone with acquired drug resistance and tumor metastasis

Cancer reports, 2022-12, Vol.5 (12), p.e1261-n/a

2022

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Hsp90 and its mitochondrial homologue TRAP-1 independently regulate hypoxia adaptations in Caenorhabditis elegans

Mitochondrion, 2021-09, Vol.60, p.101-111

2021

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Hsp60 Chaperonin Acts as Barrier to Pharmacologically Induced Oxidative Stress Mediated Apoptosis in Tumor Cells with Differential Stress Response

Drug Target Insights, 2013-01, Vol.2013 (2013), p.35-51

2013

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Development of Nanocarrier-Based Mitochondrial Chaperone, TRAP‑1 Inhibitor to Combat Cancer Metabolism

ACS applied bio materials, 2020-07, Vol.3 (7), p.4188-4197

2020

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Hsp90 inhibition induces destabilization of actin cytoskeleton in tumor cells:functional significance of Hsp90 interaction with F-actin

Asian Pacific journal of tropical medicine, 2010-09, Vol.3 (9), p.715-722

2010

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Pharmacological inhibition of Hsp90 as a novel antitumor strategy to target cytoarchitecture through extracellular matrix signaling

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2011-09, Vol.7 (5), p.454

2011

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Inhibition of Hsp90: a new strategy for inhibiting protein kinases

BBA - Proteins and Proteomics, 2004-03, Vol.1697 (1-2), p.233-242

2004

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Cancer vs. SARS-CoV-2 induced inflammation, overlapping functions, and pharmacological targeting

Inflammopharmacology, 2021-04, Vol.29 (2), p.343-366

Amere Subbarao, Sreedhar

2021

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Hsp70 confines tumor progression of rat histiocytoma and impedes the cytotoxicity induced by natural killer cells and peritoneal macrophages

Asian Pacific journal of tropical medicine, 2010-04, Vol.3 (4), p.302-309

Sreedhar, Amere Subbarao

2010

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17AAG Treatment Accelerates Doxorubicin Induced Cellular Senescence: Hsp90 Interferes with Enforced Senescence of Tumor Cells

Drug Target Insights, 2012-01, Vol.2012 (2012), p.19-39

2012

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Heat shock proteins in the regulation of apoptosis: new strategies in tumor therapy: a comprehensive review

Pharmacology & therapeutics (Oxford), 2004-03, Vol.101 (3), p.227-257

2004

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Mitochondrial chaperone, TRAP1 as a potential pharmacological target to combat cancer metabolism

Mitochondrion, 2020-01, Vol.50, p.42-50

2020

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Heat shock proteins in the regulation of apoptosis: new strategies in tumor therapy

Pharmacology & therapeutics (Oxford), 2004-03, Vol.101 (3), p.227-257

2004

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Analysis and functional relevance of the chaperone TRAP-1 interactome in the metabolic regulation and mitochondrial integrity of cancer cells

Hsp90 chaperone facilitates E2F1/2-dependent gene transcription in human breast cancer cells

Heat shock transcription factor HSF2 modulates the autophagy response through the BTG2-SOD2 axis

Hsp90 isoforms: functions, expression and clinical importance

The mitochondrial chaperone TRAP-1 regulates the glutamine metabolism in tumor cells

Hsp90 regulates HDAC3-dependent gene transcription while HDAC3 regulates the functions of Hsp90

The conformation-specific Hsp90 inhibition interferes with the oncogenic RAF kinase adaptation and triggers premature cellular senescence, hence, acts as a tumor suppressor mechanism

Hsp90 facilitates acquired drug resistance of tumor cells through cholesterol modulation however independent of tumor progression

Corrigendum to “Hsp90 chaperone facilitates E2F1/2-dependent gene transcription in human breast cancer cells” [Eur. J. Cell Biol. 100 (2021) 151148]

Compromising the constitutive p16INK4a expression sensitizes human neuroblastoma cells to Hsp90 inhibition and promotes premature senescence

Altered molecular pathways decides the treatment outcome of Hsp90 inhibitors against breast cancer cells

Mitochondrial chaperone, TRAP1 modulates mitochondrial dynamics and promotes tumor metastasis

The matrix metalloproteinase 7 (MMP7) links Hsp90 chaperone with acquired drug resistance and tumor metastasis

Hsp90 and its mitochondrial homologue TRAP-1 independently regulate hypoxia adaptations in Caenorhabditis elegans

Hsp60 Chaperonin Acts as Barrier to Pharmacologically Induced Oxidative Stress Mediated Apoptosis in Tumor Cells with Differential Stress Response

Development of Nanocarrier-Based Mitochondrial Chaperone, TRAP‑1 Inhibitor to Combat Cancer Metabolism

Hsp90 inhibition induces destabilization of actin cytoskeleton in tumor cells:functional significance of Hsp90 interaction with F-actin

Pharmacological inhibition of Hsp90 as a novel antitumor strategy to target cytoarchitecture through extracellular matrix signaling

Inhibition of Hsp90: a new strategy for inhibiting protein kinases

Cancer vs. SARS-CoV-2 induced inflammation, overlapping functions, and pharmacological targeting

Hsp70 confines tumor progression of rat histiocytoma and impedes the cytotoxicity induced by natural killer cells and peritoneal macrophages

17AAG Treatment Accelerates Doxorubicin Induced Cellular Senescence: Hsp90 Interferes with Enforced Senescence of Tumor Cells

Heat shock proteins in the regulation of apoptosis: new strategies in tumor therapy: a comprehensive review

Mitochondrial chaperone, TRAP1 as a potential pharmacological target to combat cancer metabolism

Heat shock proteins in the regulation of apoptosis: new strategies in tumor therapy

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