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Genome-wide single-molecule analysis of long-read DNA methylation reveals heterogeneous patterns at heterochromatin that reflect nucleosome organisation

PLoS genetics, 2023-10, Vol.19 (10), p.e1010958-e1010958

2023

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An epigenetic predictor of death captures multi-modal measures of brain health

Molecular psychiatry, 2021-08, Vol.26 (8), p.3806-3816

2021

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Transcription factor binding predicts histone modifications in human cell lines

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (37), p.13367-13372

2014

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Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

Genome research, 2012-03, Vol.22 (3), p.467-477

2012

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De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands

Nature communications, 2021-01, Vol.12 (1), p.694-13, Article 694

2021

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Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation

Nature communications, 2020-07, Vol.11 (1), p.3671-17, Article 3671

2020

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The DNMT3A ADD domain is required for efficient de novo DNA methylation and maternal imprinting in mouse oocytes

PLoS genetics, 2023-08, Vol.19 (8), p.e1010855-e1010855

2023

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Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination

Molecular cell, 2010-05, Vol.38 (3), p.452-464

2010

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Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression

Nucleic acids research, 2012-06, Vol.40 (11), p.4794-4803

2012

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Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions

Genome Biology, 2017-03, Vol.18 (1), p.58-58, Article 58

2017

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Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions

Nature genetics, 2019-01, Vol.51 (1), p.96-105

2019

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Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators

Genes & development, 2017-04, Vol.31 (8), p.757-773

2017

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Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

Nature communications, 2019-03, Vol.10 (1), p.1383-1383, Article 1383

2019

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Analysis of Active and Inactive X Chromosome Architecture Reveals the Independent Organization of 30 nm and Large-Scale Chromatin Structures

Molecular cell, 2010-11, Vol.40 (3), p.397-409

2010

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The role of chromatin structure in regulating the expression of clustered genes

Nature reviews. Genetics, 2005-10, Vol.6 (10), p.775-781

2005

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Recruitment to the nuclear periphery can alter expression of genes in human cells

PLoS genetics, 2008-03, Vol.4 (3), p.e1000039-e1000039

2008

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Germline de novo mutations in families with Mendelian cancer syndromes caused by defects in DNA repair

Nature communications, 2023-06, Vol.14 (1), p.3636-3636, Article 3636

2023

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Local CpG density affects the trajectory and variance of age-associated DNA methylation changes

Genome Biology, 2022-10, Vol.23 (1), p.216-28, Article 216

2022

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Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (11), p.4364-4369

2011

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Author Correction: Germline de novo mutations in families with Mendelian cancer syndromes caused by defects in DNA repair

Nature communications, 2023-06, Vol.14 (1), p.3836-3836, Article 3836

2023

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In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma

Cancer research (Chicago, Ill.), 2022-04, Vol.82 (8), p.1548-1559

2022

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Genotype effects contribute to variation in longitudinal methylome patterns in older people

Genome medicine, 2018-10, Vol.10 (1), p.75-75, Article 75

2018

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Publisher Correction: Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

Nature communications, 2019-05, Vol.10 (1), p.2069-2069, Article 2069

2019

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Variable outcome and methylation status according to CEBPA mutant type in double-mutated acute myeloid leukemia patients and the possible implications for treatment

Haematologica (Roma), 2018-01, Vol.103 (1), p.91-100

2018

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Genome-wide single-molecule analysis of long-read DNA methylation reveals heterogeneous patterns at heterochromatin that reflect nucleosome organisation

An epigenetic predictor of death captures multi-modal measures of brain health

Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion

Transcription factor binding predicts histone modifications in human cell lines

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands

Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation

The DNMT3A ADD domain is required for efficient de novo DNA methylation and maternal imprinting in mouse oocytes

Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination

Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression

Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions

Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions

Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators

Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

Analysis of Active and Inactive X Chromosome Architecture Reveals the Independent Organization of 30 nm and Large-Scale Chromatin Structures

The role of chromatin structure in regulating the expression of clustered genes

Recruitment to the nuclear periphery can alter expression of genes in human cells

Germline de novo mutations in families with Mendelian cancer syndromes caused by defects in DNA repair

Local CpG density affects the trajectory and variance of age-associated DNA methylation changes

Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer

Author Correction: Germline de novo mutations in families with Mendelian cancer syndromes caused by defects in DNA repair

In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma

Genotype effects contribute to variation in longitudinal methylome patterns in older people

Publisher Correction: Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

Variable outcome and methylation status according to CEBPA mutant type in double-mutated acute myeloid leukemia patients and the possible implications for treatment

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