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Impact of oncogenic pathways on evasion of antitumour immune responses

Nature reviews. Cancer, 2018-03, Vol.18 (3), p.139

2018

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Modulation of the immune microenvironment by tumor-intrinsic oncogenic signaling

The Journal of cell biology, 2020-01, Vol.219 (1), p.1

2020

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Innate immune signaling and regulation in cancer immunotherapy

Cell research, 2017-01, Vol.27 (1), p.96-108

2017

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Mechanisms of tumor escape in the context of the T-cell-inflamed and the non-T-cell-inflamed tumor microenvironment

International immunology, 2016-08, Vol.28 (8), p.383-391

Spranger, Stefani

2016

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Increased demand for NAD+ relative to ATP drives aerobic glycolysis

Molecular cell, 2021-02, Vol.81 (4), p.691-707.e6

2021

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Cancer immunotherapy strategies based on overcoming barriers within the tumor microenvironment

Current opinion in immunology, 2013-04, Vol.25 (2), p.268-276

2013

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Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy

Clinical cancer research, 2015-12, Vol.21 (24), p.5427-5433

2015

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Direct and Indirect Regulators of Epithelial-Mesenchymal Transition-Mediated Immunosuppression in Breast Carcinomas

Cancer discovery, 2021-05, Vol.11 (5), p.1286-1305

2021

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Tumor and Host Factors Controlling Antitumor Immunity and Efficacy of Cancer Immunotherapy

Advances in immunology, 2016, Vol.130, p.75-93

2016

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Mechanisms of Tumor Cell-Intrinsic Immune Evasion

Annual review of cancer biology, 2018-03, Vol.2 (1), p.213-228

2018

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Pharmacologic Inhibition of MALT1 Protease by Phenothiazines as a Therapeutic Approach for the Treatment of Aggressive ABC-DLBCL

Cancer cell, 2012-12, Vol.22 (6), p.825-837

2012

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Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma

Journal for immunotherapy of cancer, 2019-11, Vol.7 (1), p.295-295, Article 295

2019

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Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

Cell stem cell, 2020-04, Vol.26 (4), p.579-592.e6

2020

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Decoupled neoantigen cross-presentation by dendritic cells limits anti-tumor immunity against tumors with heterogeneous neoantigen expression

eLife, 2023-08, Vol.12

2023

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Abstract IA07: Impact of tumor-resident dendritic cells on antitumor immune responses

Cancer research (Chicago, Ill.), 2020-10, Vol.80 (19_Supplement), p.IA07-IA07

Spranger, Stefani

2020

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49 In situ phenotypic analysis of T cells in the tumor microenvironment of a pre-clinical model of non-small cell lung cancer (NSCLC) by tissue sectioning and whole-mount immunofluorescence imaging

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A30-A31

2020

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MYC -- a thorn in the side of cancer immunity

Cell research, 2016-06, Vol.26 (6), p.639-640

2016

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320 Tumor cell-intrinsic signaling mediates T cell exclusion and promotes resistance to checkpoint blockade therapy in non-small cell lung cancer

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A344-A344

2021

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947 The activation states of tumor-resident type 2 dendritic cells impact the strength of ovarian cancer immune responses

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1050-A1050

2023

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568 Tumor-intrinsic Sox2 signaling induces regulatory T cell-mediated CD8 T cell exclusion, promoting resistance to checkpoint blockade therapy in lung cancer

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A645-A645

2023

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Tumor Heterogeneity and Tumor Immunity: A Chicken-and-Egg Problem

Trends in immunology, 2016-06, Vol.37 (6), p.349-351

Spranger, Stefani

2016

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MHC-dressing on dendritic cells: Boosting anti-tumor immunity via unconventional tumor antigen presentation

Seminars in immunology, 2023-03, Vol.66, p.101710-101710, Article 101710

2023

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Abstract SY18-02: The relationship between Batf3-DC and antitumor T-cell responses

Cancer research (Chicago, Ill.), 2018, Vol.78 (13_Supplement), p.SY18-02-SY18-02

Spranger, Stefani

2018

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A team effort: natural killer cells on the first leg of the tumor immunity relay race

Journal for immunotherapy of cancer, 2018-07, Vol.6 (1), p.67-67, Article 67

2018

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Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

Nature (London), 2015-07, Vol.523 (7559), p.231-235

2015

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Impact of oncogenic pathways on evasion of antitumour immune responses

Modulation of the immune microenvironment by tumor-intrinsic oncogenic signaling

Innate immune signaling and regulation in cancer immunotherapy

Mechanisms of tumor escape in the context of the T-cell-inflamed and the non-T-cell-inflamed tumor microenvironment

Increased demand for NAD+ relative to ATP drives aerobic glycolysis

Cancer immunotherapy strategies based on overcoming barriers within the tumor microenvironment

Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy

Direct and Indirect Regulators of Epithelial-Mesenchymal Transition-Mediated Immunosuppression in Breast Carcinomas

Tumor and Host Factors Controlling Antitumor Immunity and Efficacy of Cancer Immunotherapy

Mechanisms of Tumor Cell-Intrinsic Immune Evasion

Pharmacologic Inhibition of MALT1 Protease by Phenothiazines as a Therapeutic Approach for the Treatment of Aggressive ABC-DLBCL

Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma

Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

Decoupled neoantigen cross-presentation by dendritic cells limits anti-tumor immunity against tumors with heterogeneous neoantigen expression

Abstract IA07: Impact of tumor-resident dendritic cells on antitumor immune responses

49 In situ phenotypic analysis of T cells in the tumor microenvironment of a pre-clinical model of non-small cell lung cancer (NSCLC) by tissue sectioning and whole-mount immunofluorescence imaging

MYC -- a thorn in the side of cancer immunity

320 Tumor cell-intrinsic signaling mediates T cell exclusion and promotes resistance to checkpoint blockade therapy in non-small cell lung cancer

947 The activation states of tumor-resident type 2 dendritic cells impact the strength of ovarian cancer immune responses

568 Tumor-intrinsic Sox2 signaling induces regulatory T cell-mediated CD8 T cell exclusion, promoting resistance to checkpoint blockade therapy in lung cancer

Tumor Heterogeneity and Tumor Immunity: A Chicken-and-Egg Problem

MHC-dressing on dendritic cells: Boosting anti-tumor immunity via unconventional tumor antigen presentation

Abstract SY18-02: The relationship between Batf3-DC and antitumor T-cell responses

A team effort: natural killer cells on the first leg of the tumor immunity relay race

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

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