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Activity-Based Protein Profiling in Vivo Using a Copper(I)-Catalyzed Azide-Alkyne [3 + 2] Cycloaddition

Journal of the American Chemical Society, 2003-04, Vol.125 (16), p.4686-4687

2003

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A Tandem Orthogonal Proteolysis Strategy for High-Content Chemical Proteomics

Journal of the American Chemical Society, 2005-07, Vol.127 (28), p.10018-10019

2005

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Development and Optimization of Piperidyl-1,2,3-Triazole Ureas as Selective Chemical Probes of Endocannabinoid Biosynthesis

Journal of medicinal chemistry, 2013-11, Vol.56 (21), p.8257-8269

2013

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Chemical Strategies for Activity-Based Proteomics

Chembiochem : a European journal of chemical biology, 2004-01, Vol.5 (1), p.41-47

2004

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Discovery and Optimization of Sulfonyl Acrylonitriles as Selective, Covalent Inhibitors of Protein Phosphatase Methylesterase-1

Journal of medicinal chemistry, 2011-07, Vol.54 (14), p.5229-5236

2011

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Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors

Nature reviews. Drug discovery, 2011-04, Vol.108 (17), p.6811-6816

2011

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Phosphatidylinositol 3,4,5-Trisphosphate Activity Probes for the Labeling and Proteomic Characterization of Protein Binding Partners

Biochemistry (Easton), 2011-12, Vol.50 (51), p.11143-11161

2011

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Shotgun Analysis of Integral Membrane Proteins Facilitated by Elevated Temperature

Analytical chemistry (Washington), 2007-06, Vol.79 (12), p.4613-4620

2007

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Proteomics of Integral Membrane ProteinsTheory and Application

Chemical reviews, 2007-08, Vol.107 (8), p.3687-3714

2007

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Tandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP)-a general method for mapping sites of probe modification in proteomes

Nature protocols, 2007-06, Vol.2 (6), p.1414-1425

2007

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Clickable, photoreactive inhibitors to probe the active site microenvironment of fatty acid amide hydrolase

Chemical science (Cambridge), 2012-01, Vol.3 (1), p.77-83

2012

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Rapid Development of a Potent Photo-triggered Inhibitor of the Serine Hydrolase RBBP9

Chembiochem : a European journal of chemical biology, 2012-09, Vol.13 (14), p.2082-2093

2012

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Discovery and Optimization of Piperidyl-1,2,3-Triazole Ureas as Potent, Selective, and in Vivo-Active Inhibitors of α/β-Hydrolase Domain Containing 6 (ABHD6)

Journal of medicinal chemistry, 2013-11, Vol.56 (21), p.8270-8279

2013

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Confirming Target Engagement for Reversible Inhibitors in Vivo by Kinetically Tuned Activity-Based Probes

Journal of the American Chemical Society, 2012-06, Vol.134 (25), p.10345-10348

2012

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Potent and Selective Inhibitors of Glutathione S-Transferase Omega 1 That Impair Cancer Drug Resistance

Journal of the American Chemical Society, 2011-10, Vol.133 (41), p.16605-16616

2011

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Mechanistic Characterization of a 2‑Thioxanthine Myeloperoxidase Inhibitor and Selectivity Assessment Utilizing Click Chemistry–Activity-Based Protein Profiling

Biochemistry (Easton), 2013-12, Vol.52 (51), p.9187-9201

2013

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Selective Inhibitor of Platelet-Activating Factor Acetylhydrolases 1b2 and 1b3 That Impairs Cancer Cell Survival

ACS chemical biology, 2015-04, Vol.10 (4), p.925-932

2015

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Target-Based Screen Against a Periplasmic Serine Protease That Regulates Intrabacterial pH Homeostasis in Mycobacterium tuberculosis

ACS chemical biology, 2015-02, Vol.10 (2), p.364-371

2015

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Profiling Enzyme Activities In Vivo Using Click Chemistry Methods

Chemistry & biology, 2004-04, Vol.11 (4), p.535-546

2004

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Selective inhibitors and tailored activity probes for lipoprotein-associated phospholipase A

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.839-843

2013

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Selective inhibitors and tailored activity probes for lipoprotein-associated phospholipase A2

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.839-843

2013

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A Shotgun Proteomic Method for the Identification of Membrane-Embedded Proteins and Peptides

Journal of proteome research, 2008-07, Vol.7 (7), p.3028-3034

2008

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A Substrate-Free Activity-Based Protein Profiling Screen for the Discovery of Selective PREPL Inhibitors

Journal of the American Chemical Society, 2011-08, Vol.133 (30), p.11665-11674

2011

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Chromatographic benefits of elevated temperature for the proteomic analysis of membrane proteins

Proteomics (Weinheim), 2008-10, Vol.8 (19), p.3956-3964

2008

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Proteomics of Integral Membrane ProteinsTheory and Application

Chemical reviews, 2007-08, Vol.107 (8), p.3687-3714

2007

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Activity-Based Protein Profiling in Vivo Using a Copper(I)-Catalyzed Azide-Alkyne [3 + 2] Cycloaddition

A Tandem Orthogonal Proteolysis Strategy for High-Content Chemical Proteomics

Development and Optimization of Piperidyl-1,2,3-Triazole Ureas as Selective Chemical Probes of Endocannabinoid Biosynthesis

Chemical Strategies for Activity-Based Proteomics

Discovery and Optimization of Sulfonyl Acrylonitriles as Selective, Covalent Inhibitors of Protein Phosphatase Methylesterase-1

Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors

Phosphatidylinositol 3,4,5-Trisphosphate Activity Probes for the Labeling and Proteomic Characterization of Protein Binding Partners

Shotgun Analysis of Integral Membrane Proteins Facilitated by Elevated Temperature

Proteomics of Integral Membrane ProteinsTheory and Application

Tandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP)-a general method for mapping sites of probe modification in proteomes

Clickable, photoreactive inhibitors to probe the active site microenvironment of fatty acid amide hydrolase

Rapid Development of a Potent Photo-triggered Inhibitor of the Serine Hydrolase RBBP9

Discovery and Optimization of Piperidyl-1,2,3-Triazole Ureas as Potent, Selective, and in Vivo-Active Inhibitors of α/β-Hydrolase Domain Containing 6 (ABHD6)

Confirming Target Engagement for Reversible Inhibitors in Vivo by Kinetically Tuned Activity-Based Probes

Potent and Selective Inhibitors of Glutathione S-Transferase Omega 1 That Impair Cancer Drug Resistance

Mechanistic Characterization of a 2‑Thioxanthine Myeloperoxidase Inhibitor and Selectivity Assessment Utilizing Click Chemistry–Activity-Based Protein Profiling

Selective Inhibitor of Platelet-Activating Factor Acetylhydrolases 1b2 and 1b3 That Impairs Cancer Cell Survival

Target-Based Screen Against a Periplasmic Serine Protease That Regulates Intrabacterial pH Homeostasis in Mycobacterium tuberculosis

Profiling Enzyme Activities In Vivo Using Click Chemistry Methods

Selective inhibitors and tailored activity probes for lipoprotein-associated phospholipase A

Selective inhibitors and tailored activity probes for lipoprotein-associated phospholipase A2

A Shotgun Proteomic Method for the Identification of Membrane-Embedded Proteins and Peptides

A Substrate-Free Activity-Based Protein Profiling Screen for the Discovery of Selective PREPL Inhibitors

Chromatographic benefits of elevated temperature for the proteomic analysis of membrane proteins

Proteomics of Integral Membrane ProteinsTheory and Application

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