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Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: a University of Southern California pilot program

Journal of clinical oncology, 1992-12, Vol.10 (12), p.1933-1942

1992

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Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial

European journal of cancer (1990), 1995-07, Vol.31 (7), p.1306-1310

1995

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Active specific immunotherapy of metastatic melanoma with an antiidiotype vaccine: a phase I/II trial of I-Mel-2 plus SAF-m

Journal of clinical oncology, 1997-05, Vol.15 (5), p.2103-2110

1997

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Restoration of wild-type p53 activity in p53-null HL-60 cells confers multidrug sensitivity

Clinical cancer research, 1998-05, Vol.4 (5), p.1315-1322

1998

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Prolonged Continuous Infusion of Fluorouracil With Weekly Bolus Leucovorin: A Phase II Study in Patients With Disseminated Colorectal Cancer

JNCI : Journal of the National Cancer Institute, 1993-01, Vol.85 (1), p.41-44

1993

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Mutagenicity studies of methyl- tert-butylether using the Ames tester strain TA102

Mutation research, 1999-10, Vol.446 (1), p.15-21

1999

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Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I

Haematologica (Roma), 2015-04, Vol.100 (4), p.479-488

2015

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Mechanisms of innate resistance to thymidylate synthase inhibition after 5-fluorouracil

Cancer research (Chicago, Ill.), 1988-10, Vol.48 (20), p.5894-5900

1988

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Clinical Resistance to Antimetabolites

Hematology/oncology clinics of North America, 1995-04, Vol.9 (2), p.397-414

Paul Spears, Colin

1995

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5-fluorouracil (5-FU) and 5,10-methylene tetrahydrofolate (5,10-CH2FH4) as adjuvant therapy in an experimental rodent colon carcinoma model

Anticancer research, 1997-09, Vol.17 (5A), p.3671

1997

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Thymidylate Synthase in Advanced Gastrointestinal and Breast Cancers

Acta oncologica, 1996, Vol.35 (4), p.469-472

1996

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5-Fluorouracil sensitive adenocarcinoma--a new experimental model in the rat

Anticancer research, 1995-03, Vol.15 (2), p.433

1995

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Synthesis and biological activities of novel 5-(2-acylethynyl)uracils

Journal of medicinal chemistry, 1990-07, Vol.33 (7), p.1975-1979

1990

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Oral Food Challenges in Children with a Diagnosis of Food Allergy

The Journal of pediatrics, 2011-04, Vol.158 (4), p.578-583.e1

2011

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Biochemical Determinants of Tumor Sensitivity to 5-fluorouracil: Ultrasensitive Methods for the Determination of 5-fluoro-2′-deoxyuridylate, 2′-deoxyuridylate, and Thymidylate Synthetase

Proceedings of the National Academy of Sciences - PNAS, 1979-03, Vol.76 (3), p.1456-1460

1979

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Structure of ethyl phenyl selenone

Acta crystallographica. Section C, Crystal structure communications, 1993-03, Vol.49 (3), p.520-523

1993

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Phenyl selenones: alkyl transfer by selenium-carbon bond cleavage

Journal of medicinal chemistry, 1990-06, Vol.33 (6), p.1544-1547

1990

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Assay and time course of 5-fluorouracil incorporation into RNA of L1210/0 ascites cells in vivo

Molecular pharmacology, 1985-02, Vol.27 (2), p.302-307

1985

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Volume doubling approach to tumor measurement

Journal of clinical oncology, 1985-11, Vol.3 (11), p.1563-1563

Spears, C P

1985

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5-(Acylethynyl)uracils, 5-(Acylethynyl)-2'-deoxyuridines and 5-(Acylethynyl)-1-(2-hydroxyethoxy)methyluracils. Their synthesis, antiviral and cytotoxic activities

European journal of medicinal chemistry, 1999, Vol.34 (5), p.389-398

1999

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Deoxyuridylate effects on thymidylate synthase-5-fluorodeoxyuridylate-folate ternary complex formation

Biochemical pharmacology, 1989-09, Vol.38 (18), p.2985-2993

1989

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Chemical Stability and Human Plasma Pharmacokinetics of Reduced Folates

Cancer investigation, 1998, Vol.16 (7), p.447-455

1998

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Intraperitoneal 5-fluoro-2'-deoxyuridine with escalating doses of leucovorin : pharmacology and clinical tolerance

Investigational new drugs, 1994-01, Vol.12 (3), p.197-206

1994

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Structure–Activity Studies on Organoselenium Alkylating Agents

Journal of pharmaceutical sciences, 1990-01, Vol.79 (1), p.57-62

1990

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Folinic acid modulation of fluorouracil: tissue kinetics of bolus administration

Investigational new drugs, 1989-04, Vol.7 (1), p.27-36

1989

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Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: a University of Southern California pilot program

Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial

Active specific immunotherapy of metastatic melanoma with an antiidiotype vaccine: a phase I/II trial of I-Mel-2 plus SAF-m

Restoration of wild-type p53 activity in p53-null HL-60 cells confers multidrug sensitivity

Prolonged Continuous Infusion of Fluorouracil With Weekly Bolus Leucovorin: A Phase II Study in Patients With Disseminated Colorectal Cancer

Mutagenicity studies of methyl- tert-butylether using the Ames tester strain TA102

Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I

Mechanisms of innate resistance to thymidylate synthase inhibition after 5-fluorouracil

Clinical Resistance to Antimetabolites

5-fluorouracil (5-FU) and 5,10-methylene tetrahydrofolate (5,10-CH2FH4) as adjuvant therapy in an experimental rodent colon carcinoma model

Thymidylate Synthase in Advanced Gastrointestinal and Breast Cancers

5-Fluorouracil sensitive adenocarcinoma--a new experimental model in the rat

Synthesis and biological activities of novel 5-(2-acylethynyl)uracils

Oral Food Challenges in Children with a Diagnosis of Food Allergy

Biochemical Determinants of Tumor Sensitivity to 5-fluorouracil: Ultrasensitive Methods for the Determination of 5-fluoro-2′-deoxyuridylate, 2′-deoxyuridylate, and Thymidylate Synthetase

Structure of ethyl phenyl selenone

Phenyl selenones: alkyl transfer by selenium-carbon bond cleavage

Assay and time course of 5-fluorouracil incorporation into RNA of L1210/0 ascites cells in vivo

Volume doubling approach to tumor measurement

5-(Acylethynyl)uracils, 5-(Acylethynyl)-2'-deoxyuridines and 5-(Acylethynyl)-1-(2-hydroxyethoxy)methyluracils. Their synthesis, antiviral and cytotoxic activities

Deoxyuridylate effects on thymidylate synthase-5-fluorodeoxyuridylate-folate ternary complex formation

Chemical Stability and Human Plasma Pharmacokinetics of Reduced Folates

Intraperitoneal 5-fluoro-2'-deoxyuridine with escalating doses of leucovorin : pharmacology and clinical tolerance

Structure–Activity Studies on Organoselenium Alkylating Agents

Folinic acid modulation of fluorouracil: tissue kinetics of bolus administration

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