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The enemy within: Targeting host-parasite interaction for antileishmanial drug discovery

PLoS neglected tropical diseases, 2017-06, Vol.11 (6), p.e0005480-e0005480

2017

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Leishmania allelic selection during experimental sand fly infection correlates with mutational signatures of oxidative DNA damage

Proceedings of the National Academy of Sciences - PNAS, 2023-03, Vol.120 (10), p.e2220828120-e2220828120

2023

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Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response

Cell reports (Cambridge), 2020-02, Vol.30 (6), p.1870-1882.e4

2020

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Dynamic imaging reveals surface exposure of virulent Leishmania amastigotes during pyroptosis of infected macrophages

Journal of cell science, 2021-03, Vol.134 (5)

2021

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Joining forces: first application of a rapamycin‐induced dimerizable Cre system for conditional null mutant analysis in Leishmania

Molecular microbiology, 2016-06, Vol.100 (6), p.923-927

2016

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Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion

Frontiers in cellular and infection microbiology, 2021-03, Vol.11, p.655700

2021

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Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification

Cell reports (Cambridge), 2024-05, Vol.43 (5), p.114203, Article 114203

2024

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Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit

BioMed research international, 2017-01, Vol.2017, p.4635605-11

2017

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Genome instability drives epistatic adaptation in the human pathogen Leishmania

Proceedings of the National Academy of Sciences - PNAS, 2021-12, Vol.118 (51)

2021

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Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines

Parasites & vectors, 2020-11, Vol.13 (1), p.1-600, Article 600

2020

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Intracellular persistence of Leishmania tarentolae in primary canine macrophage cells

Acta tropica, 2023-07, Vol.243, p.106935-106935, Article 106935

2023

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Leishmania donovani 90 kD Heat Shock Protein - Impact of Phosphosites on Parasite Fitness, Infectivity and Casein Kinase Affinity

Scientific reports, 2019-03, Vol.9 (1), p.5074, Article 5074

2019

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Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor

European journal of medicinal chemistry, 2017-01, Vol.125, p.696-709

2017

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Drug Discovery for Kinetoplastid Diseases: Future Directions

ACS infectious diseases, 2019-02, Vol.5 (2), p.152-157

2019

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A comparative genomics approach reveals a local genetic signature of Leishmania tropica in Morocco

Microbial genomics, 2024-04, Vol.10 (4)

2024

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Old World cutaneous leishmaniasis challenges in Morocco, Algeria, Tunisia and Iran (MATI): a collaborative attempt to combat the disease

Expert review of vaccines, 2017-05, Vol.16 (5), p.415-417

2017

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Reverse Epidemiology: An Experimental Framework to Drive Leishmania Biomarker Discovery in situ by Functional Genetic Screening Using Relevant Animal Models

Frontiers in cellular and infection microbiology, 2018-09, Vol.8, p.325-325

2018

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Retrospective Analysis of Leishmaniasis in Sicily (Italy) from 2013 to 2021: One-Health Impact and Future Control Strategies

Microorganisms (Basel), 2022-08, Vol.10 (9), p.1704

2022

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Infectivity and Drug Susceptibility Profiling of Different Leishmania -Host Cell Combinations

Pathogens (Basel), 2020-05, Vol.9 (5), p.393

2020

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GIP: an open-source computational pipeline for mapping genomic instability from protists to cancer cells

Nucleic acids research, 2022-04, Vol.50 (6), p.e36

2022

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Lipophosphoglycan Is a Virulence Factor Distinct from Related Glycoconjugates in the Protozoan Parasite Leishmania major

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (16), p.9258-9263

2000

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Trifloxystrobin blocks the growth of Theileria parasites and is a promising drug to treat Buparvaquone resistance

Communications biology, 2022-11, Vol.5 (1), p.1253-1253, Article 1253

2022

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Nuclear and mitochondrial genome sequencing of North-African Leishmania infantum isolates from cured and relapsed visceral leishmaniasis patients reveals variations correlating with geography and phenotype

Microbial genomics, 2020-10, Vol.6 (10)

2020

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Trans-Atlantic Spillover: Deconstructing the Ecological Adaptation of Leishmania infantum in the Americas

Genes, 2020-01, Vol.11 (1), p.4

2020

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The enemy within: Targeting host-parasite interaction for antileishmanial drug discovery

Leishmania allelic selection during experimental sand fly infection correlates with mutational signatures of oxidative DNA damage

Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response

Dynamic imaging reveals surface exposure of virulent Leishmania amastigotes during pyroptosis of infected macrophages

Joining forces: first application of a rapamycin‐induced dimerizable Cre system for conditional null mutant analysis in Leishmania

Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion

Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification

Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit

Genome instability drives epistatic adaptation in the human pathogen Leishmania

Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines

Intracellular persistence of Leishmania tarentolae in primary canine macrophage cells

Leishmania donovani 90 kD Heat Shock Protein - Impact of Phosphosites on Parasite Fitness, Infectivity and Casein Kinase Affinity

Leishmania Genome Dynamics during Environmental Adaptation Reveal Strain-Specific Differences in Gene Copy Number Variation, Karyotype Instability, and Telomeric Amplification

Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor

Drug Discovery for Kinetoplastid Diseases: Future Directions

A comparative genomics approach reveals a local genetic signature of Leishmania tropica in Morocco

Old World cutaneous leishmaniasis challenges in Morocco, Algeria, Tunisia and Iran (MATI): a collaborative attempt to combat the disease

Reverse Epidemiology: An Experimental Framework to Drive Leishmania Biomarker Discovery in situ by Functional Genetic Screening Using Relevant Animal Models

Retrospective Analysis of Leishmaniasis in Sicily (Italy) from 2013 to 2021: One-Health Impact and Future Control Strategies

Infectivity and Drug Susceptibility Profiling of Different Leishmania -Host Cell Combinations

GIP: an open-source computational pipeline for mapping genomic instability from protists to cancer cells

Lipophosphoglycan Is a Virulence Factor Distinct from Related Glycoconjugates in the Protozoan Parasite Leishmania major

Trifloxystrobin blocks the growth of Theileria parasites and is a promising drug to treat Buparvaquone resistance

Nuclear and mitochondrial genome sequencing of North-African Leishmania infantum isolates from cured and relapsed visceral leishmaniasis patients reveals variations correlating with geography and phenotype

Trans-Atlantic Spillover: Deconstructing the Ecological Adaptation of Leishmania infantum in the Americas

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