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Remodeling of the Enhancer Landscape during Macrophage Activation Is Coupled to Enhancer Transcription

Molecular cell, 2013-08, Vol.51 (3), p.310-325

2013

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Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

Cell, 2014-12, Vol.159 (6), p.1327-1340

2014

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The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

Immunity (Cambridge, Mass.), 2013-01, Vol.38 (1), p.106-118

2013

Volltextzugriff (PDF)

Control of Proinflammatory Gene Programs by Regulated Trimethylation and Demethylation of Histone H4K20

Molecular cell, 2012-10, Vol.48 (1), p.28-38

2012

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Sympathetic neuron-associated macrophages contribute to obesity by importing and metabolizing norepinephrine

Nature medicine, 2017-11, Vol.23 (11), p.1309-1318

2017

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Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis

Immunity (Cambridge, Mass.), 2020-06, Vol.52 (6), p.1057-1074.e7

2020

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NCoR Repression of LXRs Restricts Macrophage Biosynthesis of Insulin-Sensitizing Omega 3 Fatty Acids

Cell, 2013-09, Vol.155 (1), p.200-214

2013

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SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism

Cell metabolism, 2017-02, Vol.25 (2), p.412-427

2017

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Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis

Cell metabolism, 2020-01, Vol.31 (1), p.189-206.e8

2020

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Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (20), p.E4680-E4689

2018

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Diverse motif ensembles specify non-redundant DNA binding activities of AP-1 family members in macrophages

Nature communications, 2019-01, Vol.10 (1), p.414-414, Article 414

2019

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Transcription factor ISL1 is essential for pacemaker development and function

The Journal of clinical investigation, 2015-08, Vol.125 (8), p.3256-3268

2015

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Sterols and oxysterols in immune cell function

Nature immunology, 2013-09, Vol.14 (9), p.893

2013

Volltextzugriff (PDF)

ARID1B, a molecular suppressor of erythropoiesis, is essential for the prevention of Monge's disease

Experimental and Molecular Medicine, 2022, 54(0), , pp.777-787

2022

Volltextzugriff (PDF)

Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages

eLife, 2016-07, Vol.5

2016

Volltextzugriff (PDF)

Txnip balances metabolic and growth signaling via PTEN disulfide reduction

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (10), p.3921-3926

2008

Volltextzugriff (PDF)

An optimized protocol for rapid, sensitive and robust on-bead ChIP-seq from primary cells

STAR protocols, 2021-03, Vol.2 (1), p.100358-100358, Article 100358

2021

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Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity

Immunity (Cambridge, Mass.), 2019-10, Vol.51 (4), p.655-670.e8

2019

Volltextzugriff (PDF)

Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function

Cell, 2018-06, Vol.173 (7), p.1796-1809.e17

2018

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Transcriptomic and epigenetic mechanisms underlying myeloid diversity in the lung

Nature immunology, 2020-02, Vol.21 (2), p.221

2020

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FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages

The EMBO journal, 2010-12, Vol.29 (24), p.4223-4236

2010

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Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

Cell, 2015-01, Vol.160 (1-2), p.351-352

2015

Volltextzugriff (PDF)

Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes

Nature immunology, 2023-11, Vol.24 (11), p.1825

2023

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Remodeling of the Enhancer Landscape during Macrophage Activation Is Coupled to Enhancer Transcription

Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

Control of Proinflammatory Gene Programs by Regulated Trimethylation and Demethylation of Histone H4K20

Sympathetic neuron-associated macrophages contribute to obesity by importing and metabolizing norepinephrine

Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis

NCoR Repression of LXRs Restricts Macrophage Biosynthesis of Insulin-Sensitizing Omega 3 Fatty Acids

SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism

Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis

Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages

Diverse motif ensembles specify non-redundant DNA binding activities of AP-1 family members in macrophages

Transcription factor ISL1 is essential for pacemaker development and function

Sterols and oxysterols in immune cell function

ARID1B, a molecular suppressor of erythropoiesis, is essential for the prevention of Monge's disease

Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages

Txnip balances metabolic and growth signaling via PTEN disulfide reduction

An optimized protocol for rapid, sensitive and robust on-bead ChIP-seq from primary cells

Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity

Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function

Transcriptomic and epigenetic mechanisms underlying myeloid diversity in the lung

FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages

Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses

Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

Biomarkers of NAFLD progression: a lipidomics approach to an epidemic

Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes

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