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Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms

Journal of medicinal chemistry, 2017-10, Vol.60 (20), p.8268-8297

2017

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11H‑Pyrido[3′,2′:4,5]pyrrolo[3,2‑c]cinnoline and Pyrido[3′,2′:4,5]pyrrolo[1,2‑c][1,2,3]benzotriazine: Two New Ring Systems with Antitumor Activity

Journal of medicinal chemistry, 2014-11, Vol.57 (22), p.9495-9511

2014

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Marine Anticancer Agents: An Overview with a Particular Focus on Their Chemical Classes

Marine drugs, 2020-12, Vol.18 (12), p.619

2020

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Bioactive pyrrole-based compounds with target selectivity

European journal of medicinal chemistry, 2020-12, Vol.208, p.112783-112783, Article 112783

2020

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Pyrrolo[2′,3′:3,4]cyclohepta[1,2‑d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types

Journal of medicinal chemistry, 2020-10, Vol.63 (20), p.12023-12042

2020

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Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds

Topics in current chemistry (2016), 2021-10, Vol.379 (5), p.34-34, Article 34

2021

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1,3,5-Triazines: A promising scaffold for anticancer drugs development

European journal of medicinal chemistry, 2017-12, Vol.142, p.523-549

2017

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Preclinical Activity of New [1,2]Oxazolo[5,4‑e]isoindole Derivatives in Diffuse Malignant Peritoneal Mesothelioma

Journal of medicinal chemistry, 2016-08, Vol.59 (15), p.7223-7238

2016

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An overview on the recent developments of 1,2,4-triazine derivatives as anticancer compounds

European journal of medicinal chemistry, 2017-12, Vol.142, p.328-375

2017

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GPCR Inhibition in Treating Lymphoma

ACS medicinal chemistry letters, 2022-03, Vol.13 (3), p.358-364

2022

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Evaluation of Fused Pyrrolothiazole Systems as Correctors of Mutant CFTR Protein

Molecules (Basel, Switzerland), 2021-02, Vol.26 (5), p.1275

2021

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Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors

European journal of medicinal chemistry, 2021-02, Vol.212, p.113122, Article 113122

2021

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Novel 1H‑Pyrrolo[2,3‑b]pyridine Derivative Nortopsentin Analogues: Synthesis and Antitumor Activity in Peritoneal Mesothelioma Experimental Models

Journal of medicinal chemistry, 2013-09, Vol.56 (17), p.7060-7072

2013

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The New Microtubule-Targeting Agent SIX2G Induces Immunogenic Cell Death in Multiple Myeloma

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10222

2022

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Novel insights on [1,2]oxazolo[5,4‐e]isoindoles on multidrug resistant acute myeloid leukemia cell line

Drug development research, 2022-09, Vol.83 (6), p.1331-1341

2022

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Insight on pyrimido[5,4-g]indolizine and pyrimido[4,5-c]pyrrolo[1,2-a]azepine systems as promising photosensitizers on malignant cells

European journal of medicinal chemistry, 2022-07, Vol.237, p.114399-114399, Article 114399

2022

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Synthesis of 2H-Imidazo[2′,1':2,3] [1,3]thiazolo[4,5-e]isoindol-8-yl-phenylureas with promising therapeutic features for the treatment of acute myeloid leukemia (AML) with FLT3/ITD mutations

European journal of medicinal chemistry, 2022-05, Vol.235, p.114292-114292, Article 114292

2022

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Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues

European journal of medicinal chemistry, 2017-09, Vol.138, p.371-383

2017

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Insight into non-nucleoside triazole-based systems as viral polymerases inhibitors

European journal of medicinal chemistry, 2023-03, Vol.249, p.115136-115136, Article 115136

2023

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Targeting multiple myeloma with natural polyphenols

European journal of medicinal chemistry, 2019-10, Vol.180, p.465-485

2019

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Novel tricyclic pyrrolo-quinolines as pharmacological correctors of the mutant CFTR chloride channel

Scientific reports, 2023-05, Vol.13 (1), p.7604-7604, Article 7604

2023

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New Thiazole Nortopsentin Analogues Inhibit Bacterial Biofilm Formation

Marine drugs, 2018-08, Vol.16 (8), p.274

2018

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New tricyclic systems as photosensitizers towards triple negative breast cancer cells

Archives of pharmacal research, 2022-11, Vol.45 (11), p.806-821

2022

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Synthesis and Antitumor Activity of New Thiazole Nortopsentin Analogs

Marine drugs, 2016-12, Vol.14 (12), p.226-226

2016

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Identification of pyrrolo[3′,4’:3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas

European journal of medicinal chemistry, 2023-06, Vol.254, p.115372-115372, Article 115372

2023

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Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms

11H‑Pyrido[3′,2′:4,5]pyrrolo[3,2‑c]cinnoline and Pyrido[3′,2′:4,5]pyrrolo[1,2‑c][1,2,3]benzotriazine: Two New Ring Systems with Antitumor Activity

Marine Anticancer Agents: An Overview with a Particular Focus on Their Chemical Classes

Bioactive pyrrole-based compounds with target selectivity

Pyrrolo[2′,3′:3,4]cyclohepta[1,2‑d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types

Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds

1,3,5-Triazines: A promising scaffold for anticancer drugs development

Preclinical Activity of New [1,2]Oxazolo[5,4‑e]isoindole Derivatives in Diffuse Malignant Peritoneal Mesothelioma

An overview on the recent developments of 1,2,4-triazine derivatives as anticancer compounds

GPCR Inhibition in Treating Lymphoma

Evaluation of Fused Pyrrolothiazole Systems as Correctors of Mutant CFTR Protein

Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors

Novel 1H‑Pyrrolo[2,3‑b]pyridine Derivative Nortopsentin Analogues: Synthesis and Antitumor Activity in Peritoneal Mesothelioma Experimental Models

The New Microtubule-Targeting Agent SIX2G Induces Immunogenic Cell Death in Multiple Myeloma

Novel insights on [1,2]oxazolo[5,4‐e]isoindoles on multidrug resistant acute myeloid leukemia cell line

Insight on pyrimido[5,4-g]indolizine and pyrimido[4,5-c]pyrrolo[1,2-a]azepine systems as promising photosensitizers on malignant cells

Synthesis of 2H-Imidazo[2′,1':2,3] [1,3]thiazolo[4,5-e]isoindol-8-yl-phenylureas with promising therapeutic features for the treatment of acute myeloid leukemia (AML) with FLT3/ITD mutations

Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues

Insight into non-nucleoside triazole-based systems as viral polymerases inhibitors

Targeting multiple myeloma with natural polyphenols

Novel tricyclic pyrrolo-quinolines as pharmacological correctors of the mutant CFTR chloride channel

New Thiazole Nortopsentin Analogues Inhibit Bacterial Biofilm Formation

New tricyclic systems as photosensitizers towards triple negative breast cancer cells

Synthesis and Antitumor Activity of New Thiazole Nortopsentin Analogs

Identification of pyrrolo[3′,4’:3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas

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