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Identification of P-glycoprotein substrates and inhibitors among psychoactive compounds - implications for pharmacokinetics of selected substrates

Journal of pharmacy and pharmacology, 2004-08, Vol.56 (8), p.967-975

2004

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Influence of green and black tea on folic acid pharmacokinetics in healthy volunteers: potential risk of diminished folic acid bioavailability

Biopharmaceutics & drug disposition, 2008-09, Vol.29 (6), p.335-348

2008

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Species difference in the effect of grapefruit juice on intestinal absorption of talinolol between human and rat

The Journal of pharmacology and experimental therapeutics, 2010-01, Vol.332 (1), p.181-189

2010

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Concentration-Dependent Effect of Naringin on Intestinal Absorption of β₁-Adrenoceptor Antagonist Talinolol Mediated by P-Glycoprotein and Organic Anion Transporting Polypeptide (Oatp)

Pharmaceutical research, 2009-03, Vol.26 (3), p.560-567

2009

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Caco‐2 versus Caco‐2/HT29‐MTX Co‐cultured Cell Lines: Permeabilities Via Diffusion, Inside‐ and Outside‐Directed Carrier‐Mediated Transport

Journal of pharmaceutical sciences, 2000-01, Vol.89 (1), p.63-75

2000

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Inhibition of folic acid uptake by catechins and tea extracts in Caco-2 cells

Planta medica, 2007-01, Vol.73 (1), p.27-32

2007

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Effects of controlled-release on the pharmacokinetics and absorption characteristics of a compound undergoing intestinal efflux in humans

European journal of pharmaceutical sciences, 2006-11, Vol.29 (3-4), p.231-239

2006

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HPLC assays to simultaneously determine the angiotensin-AT1 antagonist losartan as well as its main and active metabolite EXP 3174 in biological material of humans and rats

Journal of pharmaceutical and biomedical analysis, 1998, Vol.16 (5), p.863-873

1998

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Characterization of binding properties to human P-glycoprotein: development of a [3H]verapamil radioligand-binding assay

The Journal of pharmacology and experimental therapeutics, 1999-01, Vol.288 (1), p.348

1999

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Predictability of the covalent binding of acidic drugs in man

Life sciences (1973), 1993, Vol.53 (8), p.PL141-PL146

1993

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Variable gastric emptying and discontinuities in drug absorption profiles: Dependence of rates and extent of cimetidine absorption on motility phase and pH

Biopharmaceutics & drug disposition, 1994-12, Vol.15 (9), p.719-746

1994

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Gemfibrozil and its oxidative metabolites: quantification of aglycones, acyl glucuronides, and covalent adducts in samples from preclinical and clinical kinetic studies

Journal of chromatography. B, Biomedical sciences and applications, 2000-05, Vol.741 (2), p.129-144

2000

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Comparative Pharmacodynamics and Pharmacokinetics of Candesartan and Losartan in Man

Journal of pharmacy and pharmacology, 2000-09, Vol.52 (9), p.1075-1083

2000

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Elucidation of phase I and phase II metabolic pathways of rhein: species differences and their potential relevance

Drug metabolism and disposition, 1997-04, Vol.25 (4), p.442

1997

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Concentration-dependent effect of naringin on intestinal absorption of beta(1)-adrenoceptor antagonist talinolol mediated by p-glycoprotein and organic anion transporting polypeptide (Oatp)

Pharmaceutical research, 2009-03, Vol.26 (3), p.560

2009

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Role of P‐glycoprotein‐mediated secretion in absorptive drug permeabiity: An approach using passive membrane permeability and affinity to P‐glycoprotein

Journal of pharmaceutical sciences, 1999-10, Vol.88 (10), p.1067-1072

1999

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Role of P-glycoprotein-mediated secretion in absorptive drug permeability : An approach using passive membrane permeability and affinity to P-glycoprotein

Journal of pharmaceutical sciences, 1999-10, Vol.88 (10), p.1067-1072

1999

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Acyl glucuronides revisited : is the glucuronidation process a toxification as well as a detoxification mechanism ?

Drug metabolism reviews, 1992, Vol.24 (1), p.5-47

1992

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Enhanced covalent binding of tolmetin to proteins in humans after multiple dosing

Clinical pharmacology and therapeutics, 1994-01, Vol.55 (1), p.21-27

1994

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Pretreatment with potent P-glycoprotein ligands may increase intestinal secretion in rats

European journal of pharmaceutical sciences, 2001-02, Vol.12 (4), p.405-415

2001

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A New Rapid and Sensitive High-Performance Liquid Chromatographic Assay for Diclofenac in Human Plasma

Archiv der Pharmazie (Weinheim), 1995, Vol.328 (3), p.257-260

1995

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Evidence for intestinal secretion as an additional clearance pathway of talinolol enantiomers : Concentration- and dose-dependent absorption in vitro and in vivo

Pharmaceutical research, 1996-04, Vol.13 (4), p.514-522

1996

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Carvedilol Stereopharmacokinetics in Rats: Affinities to Blood Constituents and Tissues

Archiv der Pharmazie (Weinheim), 1993, Vol.326 (9), p.529-533

1993

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Determination of triamterene and its main metabolite hydroxytriamterene sulfate in human urine by capillary electrophoresis using ultraviolet absorbance and laser-induced fluorescence detection

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002-03, Vol.769 (1), p.107-117

2002

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9th Conference of the Central European Division e.V. of the International Isotope Society

Journal of labelled compounds & radiopharmaceuticals, 2001-11, Vol.44 (13), p.947-985

2001

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Identification of P-glycoprotein substrates and inhibitors among psychoactive compounds - implications for pharmacokinetics of selected substrates

Influence of green and black tea on folic acid pharmacokinetics in healthy volunteers: potential risk of diminished folic acid bioavailability

Species difference in the effect of grapefruit juice on intestinal absorption of talinolol between human and rat

Concentration-Dependent Effect of Naringin on Intestinal Absorption of β₁-Adrenoceptor Antagonist Talinolol Mediated by P-Glycoprotein and Organic Anion Transporting Polypeptide (Oatp)

Caco‐2 versus Caco‐2/HT29‐MTX Co‐cultured Cell Lines: Permeabilities Via Diffusion, Inside‐ and Outside‐Directed Carrier‐Mediated Transport

Inhibition of folic acid uptake by catechins and tea extracts in Caco-2 cells

Effects of controlled-release on the pharmacokinetics and absorption characteristics of a compound undergoing intestinal efflux in humans

HPLC assays to simultaneously determine the angiotensin-AT1 antagonist losartan as well as its main and active metabolite EXP 3174 in biological material of humans and rats

Characterization of binding properties to human P-glycoprotein: development of a [3H]verapamil radioligand-binding assay

Predictability of the covalent binding of acidic drugs in man

Variable gastric emptying and discontinuities in drug absorption profiles: Dependence of rates and extent of cimetidine absorption on motility phase and pH

Gemfibrozil and its oxidative metabolites: quantification of aglycones, acyl glucuronides, and covalent adducts in samples from preclinical and clinical kinetic studies

Comparative Pharmacodynamics and Pharmacokinetics of Candesartan and Losartan in Man

Elucidation of phase I and phase II metabolic pathways of rhein: species differences and their potential relevance

Concentration-dependent effect of naringin on intestinal absorption of beta(1)-adrenoceptor antagonist talinolol mediated by p-glycoprotein and organic anion transporting polypeptide (Oatp)

Role of P‐glycoprotein‐mediated secretion in absorptive drug permeabiity: An approach using passive membrane permeability and affinity to P‐glycoprotein

Role of P-glycoprotein-mediated secretion in absorptive drug permeability : An approach using passive membrane permeability and affinity to P-glycoprotein

Acyl glucuronides revisited : is the glucuronidation process a toxification as well as a detoxification mechanism ?

Enhanced covalent binding of tolmetin to proteins in humans after multiple dosing

Pretreatment with potent P-glycoprotein ligands may increase intestinal secretion in rats

A New Rapid and Sensitive High-Performance Liquid Chromatographic Assay for Diclofenac in Human Plasma

Evidence for intestinal secretion as an additional clearance pathway of talinolol enantiomers : Concentration- and dose-dependent absorption in vitro and in vivo

Carvedilol Stereopharmacokinetics in Rats: Affinities to Blood Constituents and Tissues

Determination of triamterene and its main metabolite hydroxytriamterene sulfate in human urine by capillary electrophoresis using ultraviolet absorbance and laser-induced fluorescence detection

9th Conference of the Central European Division e.V. of the International Isotope Society

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