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The basics of preclinical drug development for neurodegenerative disease indications

BMC neurology, 2009-06, Vol.9 Suppl 1 (Suppl 1), p.S2-S2

2009

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Generation and Characterization of a Protective Monoclonal Antibody to Pseudomonas aeruginosa PcrV

The Journal of infectious diseases, 2002-07, Vol.186 (1), p.64-73

2002

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Effects of monoclonal anti-PcrV antibody on Pseudomonas aeruginosa-induced acute lung injury in a rat model

Journal of immune based therapies and vaccines, 2003-08, Vol.1 (1), p.2-2, Article 2

2003

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Therapeutic Administration of Anti-PcrV F(ab')2 in Sepsis Associated with Pseudomonas aeruginosa

The Journal of immunology (1950), 2001-11, Vol.167 (10), p.5880-5886

2001

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T Cell Epitopes of Human Myelin Oligodendrocyte Glycoprotein Identified in HLA-DR4 (DRB10401) Transgenic Mice Are Encephalitogenic and Are Presented by Human B Cells

The Journal of immunology (1950), 2001-12, Vol.167 (12), p.7119-7125

2001

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T cell epitope spreading to myelin oligodendrocyte glycoprotein in HLA-DR4 transgenic mice during experimental autoimmune encephalomyelitis

Clinical immunology (Orlando, Fla.), 2004-04, Vol.111 (1), p.53-60

2004

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Nonprofit model for drug discovery and development

Drug development research, 2007-06, Vol.68 (4), p.186-196

2007

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Developing non-viral DNA delivery systems for cancer and infectious disease

Drug Discovery Today, 2001-02, Vol.6 (4), p.186-197

2001

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Acetylcholine Receptor Peptide Recognition in HLA DR3-Transgenic Mice: In Vivo Responses Correlate with MHC-Peptide Binding

The Journal of immunology (1950), 2001-07, Vol.167 (2), p.1118-1124

2001

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Transfer Technique for Minimizing Waste of Sonified Adjuvant Emulsions

BioTechniques, 1996-01, Vol.20 (1), p.28-30

1996

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Scanning a DRB30101 (DR52a)-Restricted Epitope Cross-Presented by DR3: Overlapping Natural and Artificial Determinants in the Human Acetylcholine Receptor

The Journal of immunology (1950), 1999-04, Vol.162 (7), p.4079-4087

1999

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The double-edged cytokine sword of non-viral gene targeting to tumors

Drug discovery today, 2002-07, Vol.7 (14), p.754-755

2002

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Evidence That the Mechanism of Prenatal Germ Cell Death in the Mouse Is Apoptosis

Experimental cell research, 1993-12, Vol.209 (2), p.238-247

1993

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Clinical Trials Report: Central & Peripheral Nervous Systems: Drugs in development for the treatment of multiple sclerosis: antigen-specific therapies

Expert opinion on investigational drugs, 1996-10, Vol.5 (10), p.1331-1348

Spack, Edward G

1996

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Treatment of autoimmune diseases through manipulation of antigen presentation

Critical reviews in immunology, 1997, Vol.17 (5-6), p.529

Spack, E G

1997

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Antigen-specific therapies for the treatment of multiple sclerosis: a clinical trial update

Expert opinion on investigational drugs, 1997-11, Vol.6 (11), p.1715-1727

Spack, Edward G

1997

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Induction of tolerance in experimental autoimmune myasthenia gravis with solubilized MHC class II: Acetylcholine receptor peptide complexes

Journal of autoimmunity, 1995-12, Vol.8 (6), p.787-807

1995

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MHC-based diagnostics and therapeutics – clinical applications for disease-linked genes

Immunology today, 1999-04, Vol.20 (4), p.161-165

1999

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Preclinical and Pharmacological Studies of AG284, a Soluble HLA‐DR2:Myelin Basic Protein Peptide Complex for the Treatment of Multiple Sclerosis

CNS drug reviews, 1998-09, Vol.4 (3), p.225-246

1998

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Temporal order of DNA replication in the H-2 major histocompatibility complex of the mouse

Molecular and Cellular Biology, 1992-11, Vol.12 (11), p.5174-5188

1992

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Hydrophobic adsorption chromatography to reduce nonspecific staining by rhodamine-labeled antibodies

Analytical biochemistry, 1986-10, Vol.158 (1), p.233-237

1986

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MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGENS OF MURINE ERYTHROCYTES

SPACK, EDWARD G

1986

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Temporal Order of DNA Replication in the H-2 Major Histocompatibility Complex of the Mouse

Molecular and cellular biology, 1992-11, Vol.12 (11), p.5174-5188

1992

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The basics of preclinical drug development for neurodegenerative disease indications

Generation and Characterization of a Protective Monoclonal Antibody to Pseudomonas aeruginosa PcrV

Effects of monoclonal anti-PcrV antibody on Pseudomonas aeruginosa-induced acute lung injury in a rat model

Therapeutic Administration of Anti-PcrV F(ab')2 in Sepsis Associated with Pseudomonas aeruginosa

T Cell Epitopes of Human Myelin Oligodendrocyte Glycoprotein Identified in HLA-DR4 (DRB10401) Transgenic Mice Are Encephalitogenic and Are Presented by Human B Cells

T cell epitope spreading to myelin oligodendrocyte glycoprotein in HLA-DR4 transgenic mice during experimental autoimmune encephalomyelitis

Nonprofit model for drug discovery and development

Developing non-viral DNA delivery systems for cancer and infectious disease

Acetylcholine Receptor Peptide Recognition in HLA DR3-Transgenic Mice: In Vivo Responses Correlate with MHC-Peptide Binding

Transfer Technique for Minimizing Waste of Sonified Adjuvant Emulsions

Scanning a DRB30101 (DR52a)-Restricted Epitope Cross-Presented by DR3: Overlapping Natural and Artificial Determinants in the Human Acetylcholine Receptor

The double-edged cytokine sword of non-viral gene targeting to tumors

Evidence That the Mechanism of Prenatal Germ Cell Death in the Mouse Is Apoptosis

Clinical Trials Report: Central & Peripheral Nervous Systems: Drugs in development for the treatment of multiple sclerosis: antigen-specific therapies

Treatment of autoimmune diseases through manipulation of antigen presentation

Antigen-specific therapies for the treatment of multiple sclerosis: a clinical trial update

Induction of tolerance in experimental autoimmune myasthenia gravis with solubilized MHC class II: Acetylcholine receptor peptide complexes

MHC-based diagnostics and therapeutics – clinical applications for disease-linked genes

Preclinical and Pharmacological Studies of AG284, a Soluble HLA‐DR2:Myelin Basic Protein Peptide Complex for the Treatment of Multiple Sclerosis

Temporal order of DNA replication in the H-2 major histocompatibility complex of the mouse

Hydrophobic adsorption chromatography to reduce nonspecific staining by rhodamine-labeled antibodies

MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGENS OF MURINE ERYTHROCYTES

Temporal Order of DNA Replication in the H-2 Major Histocompatibility Complex of the Mouse

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