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Metformin: Mechanisms in Human Obesity and Weight Loss

Current obesity reports, 2019-06, Vol.8 (2), p.156-164

2019

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Identification of Akt-independent Regulation of Hepatic Lipogenesis by Mammalian Target of Rapamycin (mTOR) Complex 2

The Journal of biological chemistry, 2012-08, Vol.287 (35), p.29579-29588

2012

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Mitochondrial Permeability Uncouples Elevated Autophagy and Lifespan Extension

Cell, 2019-04, Vol.177 (2), p.299-314.e16

2019

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C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles

Cell metabolism, 2009-11, Vol.10 (5), p.430-435

2009

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An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer

Cell, 2016-12, Vol.167 (7), p.1705-1718.e13

2016

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Metformin as Anti-Aging Therapy: Is It for Everyone?

Trends in endocrinology and metabolism, 2019-10, Vol.30 (10), p.745-755

2019

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The fatty acid oleate is required for innate immune activation and pathogen defense in Caenorhabditis elegans

PLoS pathogens, 2019-06, Vol.15 (6), p.e1007893-e1007893

2019

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GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis

Cell, 2019-11, Vol.179 (6), p.1276-1288.e14

2019

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Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans

Genes & development, 2009-02, Vol.23 (4), p.496-511

2009

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Surviving starvation simply without TFEB

PLoS biology, 2019-05, Vol.17 (5), p.e3000285-e3000285

2019

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Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase

Cell reports (Cambridge), 2021-10, Vol.37 (1), p.109785-109785, Article 109785

2021

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Omega-3 and -6 fatty acids allocate somatic and germline lipids to ensure fitness during nutrient and oxidative stress in Caenorhabditis elegans

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (50), p.15378-15383

2015

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Genetic regulation of Caenorhabditis elegans lysosome related organelle function

PLoS genetics, 2013-10, Vol.9 (10), p.e1003908-e1003908

2013

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Role for Stearoyl-CoA Desaturase-1 in Leptin-Mediated Weight Loss

Science (American Association for the Advancement of Science), 2002-07, Vol.297 (5579), p.240-243

2002

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Genome-wide RNAi Screen for Fat Regulatory Genes in C. elegans Identifies a Proteostasis-AMPK Axis Critical for Starvation Survival

Cell reports (Cambridge), 2017-07, Vol.20 (3), p.627-640

2017

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Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions

Cell death and differentiation, 2023-08, Vol.30 (8), p.1869-1885

2023

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Biochemical and high throughput microscopic assessment of fat mass in Caenorhabditis elegans

Journal of visualized experiments, 2013-03 (73)

2013

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The direct targets of metformin in diabetes and beyond

Trends in endocrinology and metabolism, 2024-09

2024

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Suppressing the dark side of autophagy

Autophagy, 2019-10, Vol.15 (10), p.1852-1853

2019

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Site and mechanism of leptin action in a rodent form of congenital lipodystrophy

The Journal of clinical investigation, 2004-02, Vol.113 (3), p.414-424

2004

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Biguanides enhance antifungal activity against Candida glabrata

Virulence, 2018-01, Vol.9 (1), p.1150-1162

2018

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GRD-1/PTR-11, the C. elegans hedgehog/patched-like morphogen-receptor pair, modulates developmental rate

Development (Cambridge), 2023-12, Vol.150 (24)

2023

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Roles of Activin A and Gpnmb in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Diabetes (New York, N.Y.), 2024-02, Vol.73 (2), p.260-279

2024

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Induction of Leptin Receptor Expression in the Liver by Leptin and Food Deprivation

The Journal of biological chemistry, 2005-03, Vol.280 (11), p.10034-10039

2005

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Metformin: Mechanisms in Human Obesity and Weight Loss

Identification of Akt-independent Regulation of Hepatic Lipogenesis by Mammalian Target of Rapamycin (mTOR) Complex 2

Mitochondrial Permeability Uncouples Elevated Autophagy and Lifespan Extension

C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles

An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer

Metformin as Anti-Aging Therapy: Is It for Everyone?

The fatty acid oleate is required for innate immune activation and pathogen defense in Caenorhabditis elegans

GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis

Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans

Surviving starvation simply without TFEB

Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase

Omega-3 and -6 fatty acids allocate somatic and germline lipids to ensure fitness during nutrient and oxidative stress in Caenorhabditis elegans

Genetic regulation of Caenorhabditis elegans lysosome related organelle function

Role for Stearoyl-CoA Desaturase-1 in Leptin-Mediated Weight Loss

Genome-wide RNAi Screen for Fat Regulatory Genes in C. elegans Identifies a Proteostasis-AMPK Axis Critical for Starvation Survival

Ether lipid biosynthesis promotes lifespan extension and enables diverse pro-longevity paradigms in Caenorhabditis elegans

Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions

Biochemical and high throughput microscopic assessment of fat mass in Caenorhabditis elegans

The direct targets of metformin in diabetes and beyond

Suppressing the dark side of autophagy

Site and mechanism of leptin action in a rodent form of congenital lipodystrophy

Biguanides enhance antifungal activity against Candida glabrata

GRD-1/PTR-11, the C. elegans hedgehog/patched-like morphogen-receptor pair, modulates developmental rate

Roles of Activin A and Gpnmb in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Induction of Leptin Receptor Expression in the Liver by Leptin and Food Deprivation

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