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The Bcl-2 specific BH3 mimetic ABT-199: a promising targeted therapy for t(11;14) multiple myeloma

Leukemia, 2014-01, Vol.28 (1), p.210-212

2014

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Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)

Cell death & disease, 2015-01, Vol.6 (1), p.e1590-e1590

2015

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Potential drug targets and progress towards pharmacologic inhibition of hepatic glucose production

Current medicinal chemistry, 2003-01, Vol.10 (2), p.123

2003

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Prospects for pharmacologic inhibition of hepatic glucose production

Current medicinal chemistry, 2003-01, Vol.10 (2), p.99

2003

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Loss in MCL-1 function sensitizes non-Hodgkin's lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)

Blood cancer journal (New York), 2015-11, Vol.5 (11), p.e368-e368

2015

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Loss in MCL-1 function sensitizes non-Hodgkin's lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)

Blood cancer journal (New York), 2016-03, Vol.6 (3), p.e403-e403

2016

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Synthesis and Crystal Structure of a Unique and Homochiral N,S-Bonded N,N ‘-Bis(tert-butanesulfinyl)amidinate Rhodium(I) Complex

Inorganic chemistry, 2001-09, Vol.40 (20), p.5299-5301

2001

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Asymmetric Synthesis of a C-3 Substituted Pipecolic Acid

Journal of organic chemistry, 2000-02, Vol.65 (4), p.1222-1224

2000

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Novel inhibitors of alpha 4 beta 1 integrin receptor interactions through library synthesis and screening

Bioorganic & medicinal chemistry letters, 1998-09, Vol.8 (17), p.2297-2302

1998

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Optimization of a somatostatin mimetic via constrained amino acid and backbone incorporation

Bioorganic & medicinal chemistry letters, 2000-12, Vol.10 (24), p.2731-2733

2000

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β-Turn mimetic library synthesis: scaffolds and applications

Tetrahedron, 2001-08, Vol.57 (35), p.7431-7448

2001

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Erratum: Loss in MCL-1 function sensitizes non-Hodgkin’s lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)

Blood cancer journal (New York), 2016-03, Vol.6 (3), p.e403-e403

2016

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The Preparation and Utility of Bis(sulfinyl)imidoamidine Ligands for the Copper-Catalyzed Diels−Alder Reaction

Journal of organic chemistry, 2003-01, Vol.68 (1), p.3-10

2003

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The Use of Three-Dimensional Shape and Electrostatic Similarity Searching in the Identification of a Melanin-Concentrating Hormone Receptor 1 Antagonist

Chemical biology & drug design, 2006-02, Vol.67 (2), p.174-176

2006

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Identification of 2-(4-Benzyloxyphenyl)-N- [1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-6-yl]acetamide, an Orally Efficacious Melanin-Concentrating Hormone Receptor 1 Antagonist for the Treatment of Obesity

Journal of medicinal chemistry, 2005-03, Vol.48 (5), p.1318-1321

2005

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Microwave-Assisted C−H Bond Activation: A Rapid Entry into Functionalized Heterocycles

Organic letters, 2003-06, Vol.5 (12), p.2131-2134

2003

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Synthesis and evaluation of urea-based indazoles as melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity

Bioorganic & medicinal chemistry letters, 2005-06, Vol.15 (11), p.2752-2757

2005

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Identification of a Potent Heterocyclic Ligand To Somatostatin Receptor Subtype 5 by the Synthesis and Screening of β-Turn Mimetic Libraries

Journal of the American Chemical Society, 1999-03, Vol.121 (9), p.1817-1825

1999

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Screening for Cardiovascular Safety: A Structure−Activity Approach for Guiding Lead Selection of Melanin Concentrating Hormone Receptor 1 Antagonists

Journal of medicinal chemistry, 2006-04, Vol.49 (7), p.2339-2352

2006

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Aminopiperidine indazoles as orally efficacious melanin concentrating hormone receptor-1 antagonists

Bioorganic & medicinal chemistry letters, 2005-12, Vol.15 (23), p.5293-5297

2005

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Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 3

Bioorganic & medicinal chemistry letters, 2004-10, Vol.14 (19), p.4883-4886

2004

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Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 2

Bioorganic & medicinal chemistry letters, 2004-10, Vol.14 (19), p.4879-4882

2004

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Long-Term Outcomes of Nonsurgical Treatment of Thumb Carpometacarpal Osteoarthritis: A Cohort Study

Journal of bone and joint surgery. American volume, 2023-12, Vol.105 (23), p.1837

2023

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Preoperative Indicators of the Effectiveness of Surgical Release in Patients with de Quervain Disease: A Prospective Cohort Study

Plastic and reconstructive surgery (1963), 2024-05, Vol.153 (5), p.952e

2024

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The Bcl-2 specific BH3 mimetic ABT-199: a promising targeted therapy for t(11;14) multiple myeloma

Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)

Potential drug targets and progress towards pharmacologic inhibition of hepatic glucose production

Prospects for pharmacologic inhibition of hepatic glucose production

Loss in MCL-1 function sensitizes non-Hodgkin's lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)

Loss in MCL-1 function sensitizes non-Hodgkin's lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)

Synthesis and Crystal Structure of a Unique and Homochiral N,S-Bonded N,N ‘-Bis(tert-butanesulfinyl)amidinate Rhodium(I) Complex

Discovery and Characterization of Aminopiperidinecoumarin Melanin Concentrating Hormone Receptor 1 Antagonists

Asymmetric Synthesis of a C-3 Substituted Pipecolic Acid

Novel inhibitors of alpha 4 beta 1 integrin receptor interactions through library synthesis and screening

Optimization of a somatostatin mimetic via constrained amino acid and backbone incorporation

β-Turn mimetic library synthesis: scaffolds and applications

Erratum: Loss in MCL-1 function sensitizes non-Hodgkin’s lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)

The Preparation and Utility of Bis(sulfinyl)imidoamidine Ligands for the Copper-Catalyzed Diels−Alder Reaction

The Use of Three-Dimensional Shape and Electrostatic Similarity Searching in the Identification of a Melanin-Concentrating Hormone Receptor 1 Antagonist

Identification of 2-(4-Benzyloxyphenyl)-N- [1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-6-yl]acetamide, an Orally Efficacious Melanin-Concentrating Hormone Receptor 1 Antagonist for the Treatment of Obesity

Microwave-Assisted C−H Bond Activation: A Rapid Entry into Functionalized Heterocycles

Synthesis and evaluation of urea-based indazoles as melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity

Identification of a Potent Heterocyclic Ligand To Somatostatin Receptor Subtype 5 by the Synthesis and Screening of β-Turn Mimetic Libraries

Screening for Cardiovascular Safety: A Structure−Activity Approach for Guiding Lead Selection of Melanin Concentrating Hormone Receptor 1 Antagonists

Aminopiperidine indazoles as orally efficacious melanin concentrating hormone receptor-1 antagonists

Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 3

Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 2

Long-Term Outcomes of Nonsurgical Treatment of Thumb Carpometacarpal Osteoarthritis: A Cohort Study

Preoperative Indicators of the Effectiveness of Surgical Release in Patients with de Quervain Disease: A Prospective Cohort Study

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