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Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa

Frontiers in chemistry, 2020-05, Vol.8, p.204

2020

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Designing a multi-component spray-dried formulation platform for pulmonary delivery of biopharmaceuticals: The use of polyol, disaccharide, polysaccharide and synthetic polymer to modify solid-state properties for glassy stabilisation

Powder technology, 2016-01, Vol.287, p.248-255

2016

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Contemporary Formulation Development for Inhaled Pharmaceuticals

Journal of pharmaceutical sciences, 2021-01, Vol.110 (1), p.66-86

2021

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Design, Synthesis, and Evaluation of New 1H‑Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections

Journal of medicinal chemistry, 2024-01, Vol.67 (2), p.1008-1023

2024

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Model-Informed Drug Development in Pulmonary Delivery: Semimechanistic Pharmacokinetic–Pharmacodynamic Modeling for Evaluation of Treatments against Chronic Pseudomonas aeruginosa Lung Infections

Molecular pharmaceutics, 2020-05, Vol.17 (5), p.1458-1469

2020

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The effect of amino acid excipients on morphology and solid-state properties of multi-component spray-dried formulations for pulmonary delivery of biomacromolecules

European journal of pharmaceutics and biopharmaceutics, 2013-02, Vol.83 (2), p.234-243

2013

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Model‐Informed Drug Development for Antimicrobials: Translational PK and PK/PD Modeling to Predict an Efficacious Human Dose for Apramycin

Clinical pharmacology and therapeutics, 2021-04, Vol.109 (4), p.1063-1073

2021

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Pulmonary and systemic pharmacokinetics of colistin methanesulfonate (CMS) and formed colistin following nebulisation of CMS among patients with ventilator-associated pneumonia

International journal of antimicrobial agents, 2022-06, Vol.59 (6), p.106588-106588, Article 106588

2022

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Population pharmacokinetics of piperacillin in plasma and subcutaneous tissue in patients on continuous renal replacement therapy

International journal of infectious diseases, 2020-03, Vol.92, p.133-140

2020

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Investigating the interactions of amino acid components on a mannitol-based spray-dried powder formulation for pulmonary delivery: A design of experiment approach

International journal of pharmaceutics, 2011-12, Vol.421 (2), p.220-229

2011

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New developments in dry powder pulmonary vaccine delivery

Trends in biotechnology (Regular ed.), 2011-04, Vol.29 (4), p.191-198

2011

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Model-Informed Drug Discovery and Development in Pulmonary Delivery: Biopharmaceutical Pharmacometric Modeling for Formulation Evaluation of Pulmonary Suspensions

ACS omega, 2020-10, Vol.5 (40), p.25733-25746

2020

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Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection

Journal of pharmaceutical sciences, 2019-01, Vol.108 (1), p.630-640

2019

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Spray-Dried Influenza Antigen with Trehalose and Leucine Produces an Aerosolizable Powder Vaccine Formulation that Induces Strong Systemic and Mucosal Immunity after Pulmonary Administration

Journal of aerosol medicine and pulmonary drug delivery, 2015-10, Vol.28 (5), p.361-371

2015

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Designing a Multicomponent Spray-Dried Formulation Platform for Pulmonary Delivery of Biomacromolecules: The Effect of Polymers on the Formation of an Amorphous Matrix for Glassy State Stabilization of Biomacromolecules

Drying technology, 2013-10, Vol.31 (13-14), p.1451-1458

2013

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Design and Evaluation of New Quinazolin-4(3H)‑one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa

ACS infectious diseases, 2021-09, Vol.7 (9), p.2666-2685

2021

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Design, Synthesis, and Evaluation of New 1H-Benzodimidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections

Journal of medicinal chemistry, 2024-01, Vol.67 (2), p.1008

2024

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Design, Synthesis, and Evaluation of New 1 H -Benzo[ d ]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections

Journal of medicinal chemistry, 2024-01, Vol.67 (2), p.1008-1023

2024

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Automated assays for thermodynamic (equilibrium) solubility determination

Drug discovery today. Technologies, 2018-07, Vol.27, p.11-19

2018

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Nanocrystalline TiO/TiCT MXene composites with a tunable work function prepared using atmospheric pressure oxygen plasma

Nanoscale, 2023-01, Vol.15 (3), p.1289-1298

2023

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Standardized multi-omics of Earth's microbiomes reveals microbial and metabolite diversity

Nature microbiology, 2022-12, Vol.7 (12), p.2128-2150

2022

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Importance of transcript levels of caspase-2 isoforms S and L for breast carcinoma progression

Future oncology (London, England), 2013-03, Vol.9 (3), p.427-438

2013

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Building Openings Construction Manual: Windows, Vents, Exterior Doors

Cremers, Jan

1, 2016

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Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa

Designing a multi-component spray-dried formulation platform for pulmonary delivery of biopharmaceuticals: The use of polyol, disaccharide, polysaccharide and synthetic polymer to modify solid-state properties for glassy stabilisation

Contemporary Formulation Development for Inhaled Pharmaceuticals

Design, Synthesis, and Evaluation of New 1H‑Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections

Model-Informed Drug Development in Pulmonary Delivery: Semimechanistic Pharmacokinetic–Pharmacodynamic Modeling for Evaluation of Treatments against Chronic Pseudomonas aeruginosa Lung Infections

The effect of amino acid excipients on morphology and solid-state properties of multi-component spray-dried formulations for pulmonary delivery of biomacromolecules

Model‐Informed Drug Development for Antimicrobials: Translational PK and PK/PD Modeling to Predict an Efficacious Human Dose for Apramycin

Pulmonary and systemic pharmacokinetics of colistin methanesulfonate (CMS) and formed colistin following nebulisation of CMS among patients with ventilator-associated pneumonia

Population pharmacokinetics of piperacillin in plasma and subcutaneous tissue in patients on continuous renal replacement therapy

Investigating the interactions of amino acid components on a mannitol-based spray-dried powder formulation for pulmonary delivery: A design of experiment approach

New developments in dry powder pulmonary vaccine delivery

Model-Informed Drug Discovery and Development in Pulmonary Delivery: Biopharmaceutical Pharmacometric Modeling for Formulation Evaluation of Pulmonary Suspensions

Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection

Spray-Dried Influenza Antigen with Trehalose and Leucine Produces an Aerosolizable Powder Vaccine Formulation that Induces Strong Systemic and Mucosal Immunity after Pulmonary Administration

Designing a Multicomponent Spray-Dried Formulation Platform for Pulmonary Delivery of Biomacromolecules: The Effect of Polymers on the Formation of an Amorphous Matrix for Glassy State Stabilization of Biomacromolecules

Design and Evaluation of New Quinazolin-4(3H)‑one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa

Design, Synthesis, and Evaluation of New 1H-Benzodimidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections

Design, Synthesis, and Evaluation of New 1 H -Benzo[ d ]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections

Automated assays for thermodynamic (equilibrium) solubility determination

Nanocrystalline TiO/TiCT MXene composites with a tunable work function prepared using atmospheric pressure oxygen plasma

Standardized multi-omics of Earth's microbiomes reveals microbial and metabolite diversity

Importance of transcript levels of caspase-2 isoforms S and L for breast carcinoma progression

Building Openings Construction Manual: Windows, Vents, Exterior Doors

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