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Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response

JCI insight, 2017-03, Vol.2 (5), p.e90780-e90780

2017

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The bile salt export pump: clinical and experimental aspects of genetic and acquired cholestatic liver disease

Seminars in liver disease, 2010-05, Vol.30 (2), p.125-133

2010

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Bile‐Derived Organoids From Patients With Primary Sclerosing Cholangitis Recapitulate Their Inflammatory Immune Profile

Hepatology (Baltimore, Md.), 2019-09, Vol.70 (3), p.871-882

2019

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Hepatic NFAT signaling regulates the expression of inflammatory cytokines in cholestasis

Journal of hepatology, 2021-03, Vol.74 (3), p.550-559

2021

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Peroxisome proliferator‐activated receptor α activates human multidrug resistance transporter 3/ATP‐binding cassette protein subfamily B4 transcription and increases rat biliary phosphatidylcholine secretion

Hepatology (Baltimore, Md.), 2014-03, Vol.59 (3), p.1030-1042

2014

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Sirtuin 1 activation alleviates cholestatic liver injury in a cholic acid–fed mouse model of cholestasis

Hepatology (Baltimore, Md.), 2016-12, Vol.64 (6), p.2151-2164

2016

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Biosynthesis and trafficking of the bile salt export pump, BSEP: Therapeutic implications of BSEP mutations

Molecular aspects of medicine, 2014-06, Vol.37, p.3-14

2014

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Deleterious effect of oltipraz on extrahepatic cholestasis in bile duct-ligated mice

Journal of hepatology, 2014-01, Vol.60 (1), p.160-166

2014

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Organic Solute Transporter Alpha Deficiency: A Disorder With Cholestasis, Liver Fibrosis, and Congenital Diarrhea

Hepatology (Baltimore, Md.), 2020-05, Vol.71 (5), p.1879-1882

2020

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A Novel Di-Leucine Motif at the N-Terminus of Human Organic Solute Transporter Beta Is Essential for Protein Association and Membrane Localization

PloS one, 2016-06, Vol.11 (6), p.e0158269

2016

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Role of Biliary Organoids in Cholestasis Research and Regenerative Medicine

Seminars in liver disease, 2021-05, Vol.41 (2), p.206-212

2021

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Patient-Derived Organoids from Human Bile: An In Vitro Method to Study Cholangiopathies

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.1981, p.363

2019

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Organic Solute Transporter, OSTα-OSTβ: Its Role in Bile Acid Transport and Cholestasis

Seminars in liver disease, 2010-05, Vol.30 (2), p.178-185

2010

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All-trans-retinoic acid improves cholestasis in α-naphthylisothiocyanate-treated rats and Mdr2-/- mice

The Journal of pharmacology and experimental therapeutics, 2014-04, Vol.349 (1), p.94-98

2014

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Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression

American journal of physiology: Gastrointestinal and liver physiology, 2010-07, Vol.299 (1), p.G126-G135

2010

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Nuclear factor erythroid 2–related factor 2 is a positive regulator of human bile salt export pump expression

Hepatology (Baltimore, Md.), 2009-11, Vol.50 (5), p.1588-1596

2009

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A C-terminal tyrosine-based motif in the bile salt export pump directs clathrin-dependent endocytosis

Hepatology (Baltimore, Md.), 2012-06, Vol.55 (6), p.1901-1911

2012

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CFTR-associated ligand is a negative regulator of Mrp2 expression

American Journal of Physiology: Cell Physiology, 2017-01, Vol.312 (1), p.C40-C46

2017

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ATP8B1 Deficiency Disrupts the Bile Canalicular Membrane Bilayer Structure in Hepatocytes, But FXR Expression and Activity Are Maintained

Gastroenterology (New York, N.Y. 1943), 2009-03, Vol.136 (3), p.1060-1069.e4

2009

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Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine

American journal of physiology: Gastrointestinal and liver physiology, 2012-05, Vol.302 (9), p.G925-G936

2012

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Mrp4-/- mice have an impaired cytoprotective response in obstructive cholestasis

Hepatology (Baltimore, Md.), 2006-05, Vol.43 (5), p.1013-1021

2006

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Human vascularized bile duct-on-a chip: a multi-cellular micro-physiological system for studying cholestatic liver disease

Biofabrication, 2023-10, Vol.16 (1), p.15004

2023

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Na+/H+ exchanger regulatory factor 1 knockout mice have an attenuated hepatic inflammatory response and are protected from cholestatic liver injury

Hepatology (Baltimore, Md.), 2015-10, Vol.62 (4), p.1227-1236

2015

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OSTα-OSTβ : A major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia

Hepatology (Baltimore, Md.), 2005-12, Vol.42 (6), p.1270-1279

2005

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Adult sea lamprey tolerates biliary atresia by altering bile salt composition and renal excretion

Hepatology (Baltimore, Md.), 2013-06, Vol.57 (6), p.2418-2426

2013

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Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response

The bile salt export pump: clinical and experimental aspects of genetic and acquired cholestatic liver disease

Bile‐Derived Organoids From Patients With Primary Sclerosing Cholangitis Recapitulate Their Inflammatory Immune Profile

Hepatic NFAT signaling regulates the expression of inflammatory cytokines in cholestasis

Peroxisome proliferator‐activated receptor α activates human multidrug resistance transporter 3/ATP‐binding cassette protein subfamily B4 transcription and increases rat biliary phosphatidylcholine secretion

Sirtuin 1 activation alleviates cholestatic liver injury in a cholic acid–fed mouse model of cholestasis

Biosynthesis and trafficking of the bile salt export pump, BSEP: Therapeutic implications of BSEP mutations

Deleterious effect of oltipraz on extrahepatic cholestasis in bile duct-ligated mice

Organic Solute Transporter Alpha Deficiency: A Disorder With Cholestasis, Liver Fibrosis, and Congenital Diarrhea

A Novel Di-Leucine Motif at the N-Terminus of Human Organic Solute Transporter Beta Is Essential for Protein Association and Membrane Localization

Role of Biliary Organoids in Cholestasis Research and Regenerative Medicine

Patient-Derived Organoids from Human Bile: An In Vitro Method to Study Cholangiopathies

Organic Solute Transporter, OSTα-OSTβ: Its Role in Bile Acid Transport and Cholestasis

All-trans-retinoic acid improves cholestasis in α-naphthylisothiocyanate-treated rats and Mdr2-/- mice

Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression

Nuclear factor erythroid 2–related factor 2 is a positive regulator of human bile salt export pump expression

A C-terminal tyrosine-based motif in the bile salt export pump directs clathrin-dependent endocytosis

CFTR-associated ligand is a negative regulator of Mrp2 expression

ATP8B1 Deficiency Disrupts the Bile Canalicular Membrane Bilayer Structure in Hepatocytes, But FXR Expression and Activity Are Maintained

Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine

Mrp4-/- mice have an impaired cytoprotective response in obstructive cholestasis

Human vascularized bile duct-on-a chip: a multi-cellular micro-physiological system for studying cholestatic liver disease

Na+/H+ exchanger regulatory factor 1 knockout mice have an attenuated hepatic inflammatory response and are protected from cholestatic liver injury

OSTα-OSTβ : A major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia

Adult sea lamprey tolerates biliary atresia by altering bile salt composition and renal excretion

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