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On the origin of Alzheimer's disease. Trials and tribulations of the amyloid hypothesis

Ageing research reviews, 2014-01, Vol.13, p.10-12

2014

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Moving beyond anti-amyloid therapy for the prevention and treatment of Alzheimer's disease

BMC neurology, 2014-09, Vol.14 (1), p.169-169, Article 169

2014

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Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C

Journal of neuroinflammation, 2019-12, Vol.16 (1), p.269-269, Article 269

2019

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CD59 Protects Primary Human Cerebrovascular Smooth Muscle Cells from Cytolytic Membrane Attack Complex

Brain sciences, 2024-06, Vol.14 (6), p.601

2024

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Cellular hormetic response to 27-hydroxycholesterol promotes neuroprotection through AICD induction of MAST4 abundance and kinase activity

Scientific reports, 2017-10, Vol.7 (1), p.13898-11, Article 13898

2017

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The Notch intracellular domain represses CRE-dependent transcription

Cellular signalling, 2015-03, Vol.27 (3), p.621-629

2015

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Cyclin-Dependent Kinase 5 Activator p25 Is Generated During Memory Formation and Is Reduced at an Early Stage in Alzheimer's Disease

Biological psychiatry (1969), 2011-07, Vol.70 (2), p.159-168

2011

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Optimistic semaphores with non-deterministic choice operation for heterogeneous manycore systems

Concurrency and computation, 2015-09, Vol.27 (14), p.3676-3701

2015

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Loss of amyloid precursor protein in a mouse model of Niemann–Pick type C disease exacerbates its phenotype and disrupts tau homeostasis

Neurobiology of disease, 2011-06, Vol.42 (3), p.349-359

2011

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Loss of Presenilin 1 is Associated with Enhanced β-Catenin Signaling and Skin Tumorigenesis

Proceedings of the National Academy of Sciences - PNAS, 2001-09, Vol.98 (19), p.10863-10868

2001

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Loss of neuronal cell cycle control as a mechanism of neurodegeneration in the Presenilin-1 Alzheimer's disease brain

Cell cycle (Georgetown, Tex.), 2008-03, Vol.7 (5), p.637-646

2008

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NIX: A case for a manycore system for cloud computing

Bell Labs technical journal, 2012-09, Vol.17 (2), p.41-54

2012

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Psychopathology and working memory‐induced activation of the prefrontal cortex in schizophrenia‐like psychosis of epilepsy: Evidence from magnetoencephalography

Psychiatry and clinical neurosciences, 2011-03, Vol.65 (2), p.183-190

2011

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SealFS: Storage-based tamper-evident logging

Computers & security, 2021-09, Vol.108, p.102325, Article 102325

2021

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SealFSv2: combining storage-based and ratcheting for tamper-evident logging

International journal of information security, 2023-04, Vol.22 (2), p.447-466

2023

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The Amyloidogenic Pathway of Amyloid Precursor Protein (APP) Is Independent of Its Cleavage by Caspases

The Journal of biological chemistry, 2001-08, Vol.276 (31), p.29045-29050

2001

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Interferon downstream signaling is activated early in pre-symptomatic Niemann-Pick disease type C

Neuroscience letters, 2019-07, Vol.706, p.43-50

2019

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Rational heterodoxy: Cholesterol reformation of the amyloid doctrine

Ageing research reviews, 2013-01, Vol.12 (1), p.282-288

2013

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Detecting and bypassing frida dynamic function call tracing: exploitation and mitigation

Journal of Computer Virology and Hacking Techniques, 2023-11, Vol.19 (4), p.503-513

2023

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The neuronal cell cycle as a mechanism of pathogenesis in Alzheimer's disease

Aging (Albany, NY.), 2009-04, Vol.1 (4), p.363-371

2009

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A Potential Role for the Amyloid Precursor Protein in the Regulation of Interferon Signaling, Cholesterol Homeostasis, and Tau Phosphorylation in Niemann-Pick Disease Type C

Genes, 2024-08, Vol.15 (8), p.1066

2024

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Differential Interferon Signaling Regulation and Oxidative Stress Responses in the Cerebral Cortex and Cerebellum Could Account for the Spatiotemporal Pattern of Neurodegeneration in Niemann-Pick Disease Type C

Genes, 2024-01, Vol.15 (1), p.101

2024

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Short-term exposure to dietary cholesterol is associated with downregulation of interleukin-15, reduced thigmotaxis and memory impairment in mice

Behavioural brain research, 2020-09, Vol.393, p.112779-112779, Article 112779

2020

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Loss of APP in mice increases thigmotaxis and is associated with elevated brain expression of IL-13 and IP-10/CXCL10

Physiology & behavior, 2021-10, Vol.240, p.113533-113533, Article 113533

2021

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Stability and Bioactivity of Chitosan as a Transfection Agent in Primary Human Cell Cultures: A Case for Chitosan-only Controls: Chitosan Modulates CD59 Expression

Carbohydrate polymers, 2017-10, Vol.180, p.376-384

2017

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On the origin of Alzheimer's disease. Trials and tribulations of the amyloid hypothesis

Moving beyond anti-amyloid therapy for the prevention and treatment of Alzheimer's disease

Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C

CD59 Protects Primary Human Cerebrovascular Smooth Muscle Cells from Cytolytic Membrane Attack Complex

Cellular hormetic response to 27-hydroxycholesterol promotes neuroprotection through AICD induction of MAST4 abundance and kinase activity

The Notch intracellular domain represses CRE-dependent transcription

Cyclin-Dependent Kinase 5 Activator p25 Is Generated During Memory Formation and Is Reduced at an Early Stage in Alzheimer's Disease

Optimistic semaphores with non-deterministic choice operation for heterogeneous manycore systems

Loss of amyloid precursor protein in a mouse model of Niemann–Pick type C disease exacerbates its phenotype and disrupts tau homeostasis

Loss of Presenilin 1 is Associated with Enhanced β-Catenin Signaling and Skin Tumorigenesis

Loss of neuronal cell cycle control as a mechanism of neurodegeneration in the Presenilin-1 Alzheimer's disease brain

NIX: A case for a manycore system for cloud computing

Psychopathology and working memory‐induced activation of the prefrontal cortex in schizophrenia‐like psychosis of epilepsy: Evidence from magnetoencephalography

SealFS: Storage-based tamper-evident logging

SealFSv2: combining storage-based and ratcheting for tamper-evident logging

The Amyloidogenic Pathway of Amyloid Precursor Protein (APP) Is Independent of Its Cleavage by Caspases

Interferon downstream signaling is activated early in pre-symptomatic Niemann-Pick disease type C

Rational heterodoxy: Cholesterol reformation of the amyloid doctrine

Detecting and bypassing frida dynamic function call tracing: exploitation and mitigation

The neuronal cell cycle as a mechanism of pathogenesis in Alzheimer's disease

A Potential Role for the Amyloid Precursor Protein in the Regulation of Interferon Signaling, Cholesterol Homeostasis, and Tau Phosphorylation in Niemann-Pick Disease Type C

Differential Interferon Signaling Regulation and Oxidative Stress Responses in the Cerebral Cortex and Cerebellum Could Account for the Spatiotemporal Pattern of Neurodegeneration in Niemann-Pick Disease Type C

Short-term exposure to dietary cholesterol is associated with downregulation of interleukin-15, reduced thigmotaxis and memory impairment in mice

Loss of APP in mice increases thigmotaxis and is associated with elevated brain expression of IL-13 and IP-10/CXCL10

Stability and Bioactivity of Chitosan as a Transfection Agent in Primary Human Cell Cultures: A Case for Chitosan-only Controls: Chitosan Modulates CD59 Expression

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