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Inhibitors of Rho kinases (ROCK) induce multiple mitotic defects and synthetic lethality in BRCA2-deficient cells

eLife, 2023-04, Vol.12

2023

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Correction: Inhibitors of Rho kinases (ROCK) induce multiple mitotic defects and synthetic lethality in BRCA2-deficient cells

eLife, 2023-11, Vol.12

2023

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PKCα Modulates Epithelial-to-Mesenchymal Transition and Invasiveness of Breast Cancer Cells Through ZEB1

Frontiers in oncology, 2019-11, Vol.9, p.1323-1323

2019

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Chromosomal Integrity after UV Irradiation Requires FANCD2-Mediated Repair of Double Strand Breaks

PLoS genetics, 2016-01, Vol.12 (1), p.e1005792

2016

Volltextzugriff (PDF)

The thiophene α-terthienylmethanol isolated from Tagetes minuta inhibits angiogenesis by targeting protein kinase C isozymes α and β2

Frontiers in pharmacology, 2022-10, Vol.13, p.1007790-1007790

2022

Volltextzugriff (PDF)

Synthetic Lethal Activity of Benzophenanthridine Alkaloids From Zanthoxylum coco Against BRCA1-Deficient Cancer Cells

Frontiers in pharmacology, 2020-12, Vol.11, p.593845-593845

2020

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Pan-Cancer Molecular Patterns and Biological Implications Associated with a Tumor-Specific Molecular Signature

Cells (Basel, Switzerland), 2020-12, Vol.10 (1), p.45

2020

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c-Jun Proto-Oncoprotein Plays a Protective Role in Lung Epithelial Cells Exposed to Staphylococcal α-Toxin

Frontiers in cellular and infection microbiology, 2018-05, Vol.8, p.170-170

2018

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PCNA-coupled p21 degradation after DNA damage: The exception that confirms the rule?

DNA repair, 2010-04, Vol.9 (4), p.358-364

2010

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Prime, Repair, Restore: The Active Role of Chromatin in the DNA Damage Response

Molecular cell, 2012-06, Vol.46 (6), p.722-734

2012

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Therapeutic opportunities for PLK1 inhibitors: Spotlight on BRCA1-deficiency and triple negative breast cancers

Mutation research, 2020-05, Vol.821, p.111693, Article 111693

2020

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Mitochondrial fusion is essential for steroid biosynthesis

PloS one, 2012-09, Vol.7 (9), p.e45829-e45829

2012

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Topical systems for the controlled release of antineoplastic Drugs: Oxidized Alginate-Gelatin Hydrogel/Unilamellar vesicles

Journal of colloid and interface science, 2023-01, Vol.629, p.1066-1080

2023

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A novel yeast-based high-throughput method for the identification of protein palmitoylation inhibitors

Open biology, 2021-08, Vol.11 (8), p.200415-200415

2021

Volltextzugriff (PDF)

Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (19), p.7344-7349

2012

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Deoxycytidine kinase (dCK) inhibition is synthetic lethal with BRCA2 deficiency

Drug resistance updates, 2023-03, Vol.67, p.100932-100932, Article 100932

2023

Volltextzugriff (PDF)

AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress

Oncogene, 2019-05, Vol.38 (22), p.4310-4324

2019

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UV-triggered p21 degradation facilitates damaged-DNA replication and preserves genomic stability

Nucleic acids research, 2013-08, Vol.41 (14), p.6942

2013

Volltextzugriff (PDF)

P53 tumor suppressor is required for efficient execution of the death program following treatment with a cytotoxic limonoid obtained from Melia azedarach

Food and chemical toxicology, 2017-11, Vol.109 (Pt 2), p.888-897

2017

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Krüppel-Like Factor 6 Is Required for Oxidative and Oncogene-Induced Cellular Senescence

Frontiers in cell and developmental biology, 2019-11, Vol.7, p.297-297

2019

Volltextzugriff (PDF)

Correction: Chromosomal Integrity after UV Irradiation Requires FANCD2-Mediated Repair of Double Strand Breaks

PLoS genetics, 2023-12, Vol.19 (12), p.e1011094-e1011094

2023

Volltextzugriff (PDF)

Development and Optimization of a Miniaturized Western Blot-Based Screening Platform to Identify Regulators of Post-Translational Modifications

High-throughput, 2019-06, Vol.8 (2), p.15

2019

Volltextzugriff (PDF)

Chromosomal Integrity after UV Irradiation Requires FANCD2-Mediated Repair of Double Strand Breaks: e1005792

PLoS genetics, 2016-01, Vol.12 (1)

2016

Volltextzugriff (PDF)

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Inhibitors of Rho kinases (ROCK) induce multiple mitotic defects and synthetic lethality in BRCA2-deficient cells

Correction: Inhibitors of Rho kinases (ROCK) induce multiple mitotic defects and synthetic lethality in BRCA2-deficient cells

PKCα Modulates Epithelial-to-Mesenchymal Transition and Invasiveness of Breast Cancer Cells Through ZEB1

Chromosomal Integrity after UV Irradiation Requires FANCD2-Mediated Repair of Double Strand Breaks

The thiophene α-terthienylmethanol isolated from Tagetes minuta inhibits angiogenesis by targeting protein kinase C isozymes α and β2

Synthetic Lethal Activity of Benzophenanthridine Alkaloids From Zanthoxylum coco Against BRCA1-Deficient Cancer Cells

Pan-Cancer Molecular Patterns and Biological Implications Associated with a Tumor-Specific Molecular Signature

c-Jun Proto-Oncoprotein Plays a Protective Role in Lung Epithelial Cells Exposed to Staphylococcal α-Toxin

PCNA-coupled p21 degradation after DNA damage: The exception that confirms the rule?

Prime, Repair, Restore: The Active Role of Chromatin in the DNA Damage Response

Therapeutic opportunities for PLK1 inhibitors: Spotlight on BRCA1-deficiency and triple negative breast cancers

Mitochondrial fusion is essential for steroid biosynthesis

Topical systems for the controlled release of antineoplastic Drugs: Oxidized Alginate-Gelatin Hydrogel/Unilamellar vesicles

A novel yeast-based high-throughput method for the identification of protein palmitoylation inhibitors

Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA

Deoxycytidine kinase (dCK) inhibition is synthetic lethal with BRCA2 deficiency

AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress

Polo-like Kinase 1 Inhibition as a Therapeutic Approach to Selectively Target BRCA1-Deficient Cancer Cells by Synthetic Lethality Induction

UV-triggered p21 degradation facilitates damaged-DNA replication and preserves genomic stability

P53 tumor suppressor is required for efficient execution of the death program following treatment with a cytotoxic limonoid obtained from Melia azedarach

Krüppel-Like Factor 6 Is Required for Oxidative and Oncogene-Induced Cellular Senescence

Correction: Chromosomal Integrity after UV Irradiation Requires FANCD2-Mediated Repair of Double Strand Breaks

Development and Optimization of a Miniaturized Western Blot-Based Screening Platform to Identify Regulators of Post-Translational Modifications

Chromosomal Integrity after UV Irradiation Requires FANCD2-Mediated Repair of Double Strand Breaks: e1005792

Ex-Vivo Testing Using Patient Micro Avatars (PMAs) Predicts Clinical Response in Acute Leukemias

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