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Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis

The Journal of clinical investigation, 2009-02, Vol.119 (2), p.315-322

2009

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truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (23), p.9350-9355

2009

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Paradoxical Elevation of High–Molecular Weight Adiponectin in Acquired Extreme Insulin Resistance Due to Insulin Receptor Antibodies

Diabetes (New York, N.Y.), 2007-06, Vol.56 (6), p.1712-1717

2007

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Analysis of Genetic Variation in Akt2/PKB-β in Severe Insulin Resistance, Lipodystrophy, Type 2 Diabetes, and Related Metabolic Phenotypes

Diabetes (New York, N.Y.), 2007-03, Vol.56 (3), p.714-719

2007

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Muscle glycogen inharmoniously regulates glycogen synthase activity, glucose uptake, and proximal insulin signaling

American journal of physiology: endocrinology and metabolism, 2006-01, Vol.290 (1), p.E154-E162

2006

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Autoimmune forms of hypoglycemia

Medicine (Baltimore), 2009-05, Vol.88 (3), p.141-153

2009

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Genetic Variants in Human Sterol Regulatory Element Binding Protein-1c in Syndromes of Severe Insulin Resistance and Type 2 Diabetes

Diabetes (New York, N.Y.), 2004-03, Vol.53 (3), p.842-846

2004

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A Family with Severe Insulin Resistance and Diabetes Due to a Mutation in AKT2

Science (American Association for the Advancement of Science), 2004-05, Vol.304 (5675), p.1325-1328

2004

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Role of Insulin Receptor Dimerization Domains in Ligand Binding, Cooperativity, and Modulation by Anti-receptor Antibodies

The Journal of biological chemistry, 2002-05, Vol.277 (19), p.16718-16725

2002

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Plasma Adiponectin as a Marker of Insulin Receptor Dysfunction

Diabetes care, 2008-05, Vol.31 (5), p.977-979

2008

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Plasma Adiponectin as a Marker of Insulin Receptor Dysfunction : Clinical utility in severe insulin resistance

Diabetes care, 2008-05, Vol.31 (5), p.977-979

2008

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Congenital leptin deficiency is associated with severe early-onset obesity in humans

Nature (London), 1997-06, Vol.387 (6636), p.903-908

1997

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Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting

Biochemical journal, 1997-10, Vol.327 ( Pt 1) (1), p.209-215

1997

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Digenic inheritance of severe insulin resistance in a human pedigree

Nature genetics, 2002-08, Vol.31 (4), p.379-384

2002

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Multiple molecular mechanisms of insulin receptor dysfunction in a patient with Donohue syndrome

Diabetes (New York, N.Y.), 1998-08, Vol.47 (8), p.1362-1364

1998

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Functional activation of mutant human insulin receptor by monoclonal antibody

The Lancet (British edition), 1996-06, Vol.347 (9015), p.1586-1590

1996

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Hybrid insulin receptors. Molecular mechanisms of negative-dominant mutations in receptor-mediated insulin resistance

Diabetes care, 1990-06, Vol.13 (6), p.576-581

1990

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Analysis of Genetic Variation in Akt2/PKB-[beta] in Severe Insulin Resistance, Lipodystrophy, Type 2 Diabetes, and Related Metabolic Phenotypes

Diabetes (New York, N.Y.), 2007-03, Vol.56 (3), p.714-719

2007

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Contraction inhibits insulin-stimulated insulin receptor substrate-1/2-associated phosphoinositide 3-kinase activity, but not protein kinase B activation or glucose uptake, in rat muscle

Biochemical journal, 2000-08, Vol.349 Pt 3 (3), p.775-781

2000

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Class II Phosphoinositide 3-Kinase Is Activated by Insulin but Not by Contraction in Skeletal Muscle

Archives of biochemistry and biophysics, 2001-12, Vol.396 (2), p.244-248

2001

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Impaired activation of phosphoinositide 3-kinase by insulin in fibroblasts from patients with severe insulin resistance and pseudoacromegaly. A disorder characterized by selective postreceptor insulin resistance

The Journal of clinical investigation, 1998-03, Vol.101 (5), p.1111-1120

1998

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Signaling-competent receptor chimeras allow mapping of major insulin receptor binding domain determinants

The Journal of biological chemistry, 1993-01, Vol.268 (2), p.1087-1094

1993

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Inhibitors of Phosphoinositide 3-Kinase Block Exocytosis but Not Endocytosis of Transferrin Receptors in 3T3-L1 Adipocytes

Biochemical and biophysical research communications, 1995-06, Vol.211 (2), p.535-539

1995

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A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity

The Journal of biological chemistry, 1992-06, Vol.267 (18), p.12955-12963

1992

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A Family with Severe Insulin Resistance and Diabetes Mellitus due to a Missense Mutation in AKT2

Science (American Association for the Advancement of Science), 2004-05, Vol.304 (5675), p.1325-1328

2004

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Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis

truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia

Paradoxical Elevation of High–Molecular Weight Adiponectin in Acquired Extreme Insulin Resistance Due to Insulin Receptor Antibodies

Analysis of Genetic Variation in Akt2/PKB-β in Severe Insulin Resistance, Lipodystrophy, Type 2 Diabetes, and Related Metabolic Phenotypes

Muscle glycogen inharmoniously regulates glycogen synthase activity, glucose uptake, and proximal insulin signaling

Autoimmune forms of hypoglycemia

Genetic Variants in Human Sterol Regulatory Element Binding Protein-1c in Syndromes of Severe Insulin Resistance and Type 2 Diabetes

A Family with Severe Insulin Resistance and Diabetes Due to a Mutation in AKT2

Role of Insulin Receptor Dimerization Domains in Ligand Binding, Cooperativity, and Modulation by Anti-receptor Antibodies

Plasma Adiponectin as a Marker of Insulin Receptor Dysfunction

Plasma Adiponectin as a Marker of Insulin Receptor Dysfunction : Clinical utility in severe insulin resistance

Congenital leptin deficiency is associated with severe early-onset obesity in humans

Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting

Digenic inheritance of severe insulin resistance in a human pedigree

Multiple molecular mechanisms of insulin receptor dysfunction in a patient with Donohue syndrome

Functional activation of mutant human insulin receptor by monoclonal antibody

Hybrid insulin receptors. Molecular mechanisms of negative-dominant mutations in receptor-mediated insulin resistance

Analysis of Genetic Variation in Akt2/PKB-[beta] in Severe Insulin Resistance, Lipodystrophy, Type 2 Diabetes, and Related Metabolic Phenotypes

Contraction inhibits insulin-stimulated insulin receptor substrate-1/2-associated phosphoinositide 3-kinase activity, but not protein kinase B activation or glucose uptake, in rat muscle

Class II Phosphoinositide 3-Kinase Is Activated by Insulin but Not by Contraction in Skeletal Muscle

Impaired activation of phosphoinositide 3-kinase by insulin in fibroblasts from patients with severe insulin resistance and pseudoacromegaly. A disorder characterized by selective postreceptor insulin resistance

Signaling-competent receptor chimeras allow mapping of major insulin receptor binding domain determinants

Inhibitors of Phosphoinositide 3-Kinase Block Exocytosis but Not Endocytosis of Transferrin Receptors in 3T3-L1 Adipocytes

A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity

A Family with Severe Insulin Resistance and Diabetes Mellitus due to a Missense Mutation in AKT2

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