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The Growing Impact of Catalysis in the Pharmaceutical Industry

Advanced synthesis & catalysis, 2011-08, Vol.353 (11-12), p.1825-1864

2011

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Asymmetric Synthesis of Active Pharmaceutical Ingredients

Chemical reviews, 2006-07, Vol.106 (7), p.2734-2793

2006

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Site-specific template generative approach for retrosynthetic planning

Nature communications, 2024-09, Vol.15 (1), p.7818-10, Article 7818

2024

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The Eight Criteria Defining a Good Chemical Manufacturing Process

Organic process research & development, 2012-11, Vol.16 (11), p.1697-1706

2012

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General and Stereoselective Method for the Synthesis of Sterically Congested and Structurally Diverse P‑Stereogenic Secondary Phosphine Oxides

Organic letters, 2017-04, Vol.19 (7), p.1796-1799

2017

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Carbon 14 synthesis of glycine transporter 1 inhibitor Iclepertin (BI 425809) and its major metabolites

Journal of labelled compounds & radiopharmaceuticals, 2023-09, Vol.66 (11), p.336-344

2023

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Efficient Asymmetric Synthesis of P‑Chiral Phosphine Oxides via Properly Designed and Activated Benzoxazaphosphinine-2-oxide Agents

Journal of the American Chemical Society, 2013-02, Vol.135 (7), p.2474-2477

2013

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Synthesis of BI 894416 and BI 1342561, two potent and selective spleen tyrosine kinase inhibitors, labeled with carbon 14 and with deuterium

Journal of labelled compounds & radiopharmaceuticals, 2023-04, Vol.66 (4-6), p.155-168

2023

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Copper-catalyzed asymmetric hydrogenation of 2-substituted ketones via dynamic kinetic resolution

Chemical science (Cambridge), 2018, Vol.9 (19), p.4505-4510

2018

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Efficient Asymmetric Synthesis of Structurally Diverse P-Stereogenic Phosphinamides for Catalyst Design

Angewandte Chemie International Edition, 2015-04, Vol.54 (18), p.5474-5477

International ed. in English, 2015

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Organometallic methods for the synthesis and functionalization of azaindoles

Chemical Society reviews, 2007-01, Vol.36 (7), p.1120-1132

2007

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Development of a concise, scalable synthesis of a CCR1 antagonist utilizing a continuous flow Curtius rearrangement

Green chemistry : an international journal and green chemistry resource : GC, 2017, Vol.19 (6), p.1454-1461

2017

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Activation of TMSCN by N-Heterocyclic Carbenes for Facile Cyanosilylation of Carbonyl Compounds

Journal of organic chemistry, 2006-02, Vol.71 (3), p.1273-1276

2006

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Efficient Iron-Catalyzed Kumada Cross-Coupling Reactions Utilizing Flow Technology under Low Catalyst Loadings

European Journal of Organic Chemistry, 2016-05, Vol.2016 (15), p.2599-2602

2016

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Synthesis of P‑Chiral Dihydrobenzooxaphospholes Through Negishi Cross-Coupling

Journal of organic chemistry, 2016-01, Vol.81 (2), p.729-736

2016

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Rhodium-Catalyzed Asymmetric Allenylation of Sulfonylimines and Application to the Stereospecific Allylic Allenylation

Advanced synthesis & catalysis, 2016-10, Vol.358 (19), p.3062-3068

2016

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N-Heterocyclic Carbene-Catalyzed Mukaiyama Aldol Reactions

Organic letters, 2007-03, Vol.9 (6), p.1013-1016

2007

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Feed-Forward Neural Network for Predicting Enantioselectivity of the Asymmetric Negishi Reaction

ACS central science, 2023-09, Vol.9 (9), p.1768-1774

2023

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Development of a Large Scale Asymmetric Synthesis of the Glucocorticoid Agonist BI 653048 BS H3PO4

Journal of organic chemistry, 2013-04, Vol.78 (8), p.3616-3635

2013

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N-Heterocyclic Carbene Catalyzed Trifluoromethylation of Carbonyl Compounds

Organic letters, 2005-05, Vol.7 (11), p.2193-2196

2005

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Design and Synthesis of Chiral Oxathiozinone Scaffolds: Efficient Synthesis of Hindered Enantiopure Sulfinamides and Sulfinyl Ketimines

Angewandte Chemie International Edition, 2013-06, Vol.52 (26), p.6713-6717

International ed. in English, 2013

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Highly Diastereoselective Zinc-Catalyzed Propargylation of tert-Butanesulfinyl Imines

Organic letters, 2010-02, Vol.12 (4), p.748-751

2010

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A Scalable and Regioselective Synthesis of 2‑Difluoromethyl Pyridines from Commodity Chemicals

Organic letters, 2014-03, Vol.16 (6), p.1724-1727

2014

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Asymmetric Methallylation of Ketones Catalyzed by a Highly Active Organocatalyst 3,3′‑F2‑BINOL

Organic letters, 2013-04, Vol.15 (7), p.1710-1713

2013

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The Growing Impact of Catalysis in the Pharmaceutical Industry

Asymmetric Synthesis of Active Pharmaceutical Ingredients

Site-specific template generative approach for retrosynthetic planning

The Eight Criteria Defining a Good Chemical Manufacturing Process

Computationally Assisted Mechanistic Investigation and Development of Pd-Catalyzed Asymmetric Suzuki–Miyaura and Negishi Cross-Coupling Reactions for Tetra-ortho-Substituted Biaryl Synthesis

General and Stereoselective Method for the Synthesis of Sterically Congested and Structurally Diverse P‑Stereogenic Secondary Phosphine Oxides

Carbon 14 synthesis of glycine transporter 1 inhibitor Iclepertin (BI 425809) and its major metabolites

Efficient Asymmetric Synthesis of P‑Chiral Phosphine Oxides via Properly Designed and Activated Benzoxazaphosphinine-2-oxide Agents

Synthesis of BI 894416 and BI 1342561, two potent and selective spleen tyrosine kinase inhibitors, labeled with carbon 14 and with deuterium

Copper-catalyzed asymmetric hydrogenation of 2-substituted ketones via dynamic kinetic resolution

Efficient Asymmetric Synthesis of Structurally Diverse P-Stereogenic Phosphinamides for Catalyst Design

Organometallic methods for the synthesis and functionalization of azaindoles

Development of a concise, scalable synthesis of a CCR1 antagonist utilizing a continuous flow Curtius rearrangement

Activation of TMSCN by N-Heterocyclic Carbenes for Facile Cyanosilylation of Carbonyl Compounds

Efficient Iron-Catalyzed Kumada Cross-Coupling Reactions Utilizing Flow Technology under Low Catalyst Loadings

Synthesis of P‑Chiral Dihydrobenzooxaphospholes Through Negishi Cross-Coupling

Rhodium-Catalyzed Asymmetric Allenylation of Sulfonylimines and Application to the Stereospecific Allylic Allenylation

N-Heterocyclic Carbene-Catalyzed Mukaiyama Aldol Reactions

Feed-Forward Neural Network for Predicting Enantioselectivity of the Asymmetric Negishi Reaction

Development of a Large Scale Asymmetric Synthesis of the Glucocorticoid Agonist BI 653048 BS H3PO4

N-Heterocyclic Carbene Catalyzed Trifluoromethylation of Carbonyl Compounds

Design and Synthesis of Chiral Oxathiozinone Scaffolds: Efficient Synthesis of Hindered Enantiopure Sulfinamides and Sulfinyl Ketimines

Highly Diastereoselective Zinc-Catalyzed Propargylation of tert-Butanesulfinyl Imines

A Scalable and Regioselective Synthesis of 2‑Difluoromethyl Pyridines from Commodity Chemicals

Asymmetric Methallylation of Ketones Catalyzed by a Highly Active Organocatalyst 3,3′‑F2‑BINOL

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