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An early endosome regulator, Rab5b, is an LRRK2 kinase substrate

Journal of biochemistry (Tokyo), 2015-06, Vol.157 (6), p.485-495

2015

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Nuclear α-Synuclein-Derived Cytotoxic Effect via Altered Ribosomal RNA Processing in Primary Mouse Embryonic Fibroblasts

International journal of molecular sciences, 2023-01, Vol.24 (3), p.2132

2023

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Expression of transduced nucleolin promotes the clearance of accumulated α-synuclein in rodent cells and animal model

Neurobiology of disease, 2021-07, Vol.154, p.105349, Article 105349

2021

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LRRK2 Inhibition Mitigates the Neuroinflammation Caused by TLR2-Specific α-Synuclein and Alleviates Neuroinflammation-Derived Dopaminergic Neuronal Loss

Cells (Basel, Switzerland), 2022-03, Vol.11 (5), p.861

2022

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G2385R and I2020T Mutations Increase LRRK2 GTPase Activity

BioMed research international, 2016-01, Vol.2016, p.7917128-8

2016

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G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses

Animal Cells and Systems, 2019, 23(2), , pp.106-111

2019

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Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease

Parkinson's disease, 2018-01, Vol.2018, p.1241757-9

2018

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Effect of leucine-rich repeat kinase 2 (LRRK2) on protein synthesis

Animal Cells and Systems, 2018, 22(1), , pp.15-21

2018

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Analysis of α-synuclein levels related to LRRK2 kinase activity: from substantia nigra to urine of patients with Parkinson's disease

Animal Cells and Systems, 2021, 25(1), , pp.28-36

2021

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Upregulation of the p53-p21 pathway by G2019S LRRK2 contributes to the cellular senescence and accumulation of α-synuclein

Cell cycle (Georgetown, Tex.), 2019-02, Vol.18 (4), p.467-475

2019

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Mecasin treatment in patients with amyotrophic lateral sclerosis: study protocol for a randomized controlled trial

Trials, 2018-04, Vol.19 (1), p.225-225, Article 225

2018

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KCHO-1, a novel herbal anti-inflammatory compound, attenuates oxidative stress in an animal model of amyotrophic lateral sclerosis

Journal of Veterinary Science, 2017, 18(4), , pp.487-497

2017

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Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity

Animal Cells and Systems, 2018, 22(5), , pp.273-280

2018

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26-Week Repeated Dose Oral Toxicity Study of KCHO-1 in Sprague-Dawley Rats

Journal of Pharmacopuncture, 2019, 22(3), 71, pp.192-199

2019

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Characterization of Parkinson's disease-related pathogenic TMEM230 mutants

Animal Cells and Systems, 2018, 22(2), , pp.140-147

2018

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Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression

Molecular brain, 2015-09, Vol.8 (1), Article 54

2015

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Dexamethasone induces the expression of LRRK2 and α-synuclein, two genes that when mutated cause Parkinson's disease in an autosomal dominant manner

BMB Reports, 2013, 46(9), , pp.454-459

2013

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Increased DJ-1 in Urine Exosome of Korean Males with Parkinson’s Disease

BioMed research international, 2014-01, Vol.2014, p.704678-8

2014

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A study on the oral toxicity of mecasin in rats

Journal of Pharmacopuncture, 2014, 17(4), 52, pp.61-65

2014

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Efficacy of mecasin for treatment of amyotrophic lateral sclerosis: A phase IIa multicenter randomized double-blinded placebo-controlled trial

Journal of ethnopharmacology, 2023-10, Vol.315, p.116670-116670, Article 116670

2023

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A 4-week Repeated dose Oral Toxicity Study of Mecasin in Sprague-Dawley Rats to Determine the Appropriate Doses for a 13-week, Repeated Toxicity Test

Journal of Pharmacopuncture, 2015, 18(4), 56, pp.45-50

2015

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Rab GTPases as Physiological Substrates of LRRK2 Kinase

Experimental Neurobiology, 2019, 28(2), , pp.134-145

2019

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Urinary Biomarkers for Neurodegenerative Diseases

Experimental Neurobiology, 2020, 29(5), , pp.325-333

2020

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LRRK2 Kinase Inhibitor Rejuvenates Oxidative Stress-Induced Cellular Senescence in Neuronal Cells

Oxidative medicine and cellular longevity, 2021, Vol.2021, p.9969842-16

2021

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LRRK2 impairs autophagy by mediating phosphorylation of leucyl‐tRNA synthetase

Cell biochemistry and function, 2018-12, Vol.36 (8), p.431-442

2018

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An early endosome regulator, Rab5b, is an LRRK2 kinase substrate

Nuclear α-Synuclein-Derived Cytotoxic Effect via Altered Ribosomal RNA Processing in Primary Mouse Embryonic Fibroblasts

Expression of transduced nucleolin promotes the clearance of accumulated α-synuclein in rodent cells and animal model

LRRK2 Inhibition Mitigates the Neuroinflammation Caused by TLR2-Specific α-Synuclein and Alleviates Neuroinflammation-Derived Dopaminergic Neuronal Loss

G2385R and I2020T Mutations Increase LRRK2 GTPase Activity

G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses

Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease

Effect of leucine-rich repeat kinase 2 (LRRK2) on protein synthesis

Analysis of α-synuclein levels related to LRRK2 kinase activity: from substantia nigra to urine of patients with Parkinson's disease

Upregulation of the p53-p21 pathway by G2019S LRRK2 contributes to the cellular senescence and accumulation of α-synuclein

Mecasin treatment in patients with amyotrophic lateral sclerosis: study protocol for a randomized controlled trial

KCHO-1, a novel herbal anti-inflammatory compound, attenuates oxidative stress in an animal model of amyotrophic lateral sclerosis

Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity

26-Week Repeated Dose Oral Toxicity Study of KCHO-1 in Sprague-Dawley Rats

Characterization of Parkinson's disease-related pathogenic TMEM230 mutants

Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression

Dexamethasone induces the expression of LRRK2 and α-synuclein, two genes that when mutated cause Parkinson's disease in an autosomal dominant manner

Increased DJ-1 in Urine Exosome of Korean Males with Parkinson’s Disease

A study on the oral toxicity of mecasin in rats

Efficacy of mecasin for treatment of amyotrophic lateral sclerosis: A phase IIa multicenter randomized double-blinded placebo-controlled trial

A 4-week Repeated dose Oral Toxicity Study of Mecasin in Sprague-Dawley Rats to Determine the Appropriate Doses for a 13-week, Repeated Toxicity Test

Rab GTPases as Physiological Substrates of LRRK2 Kinase

Urinary Biomarkers for Neurodegenerative Diseases

LRRK2 Kinase Inhibitor Rejuvenates Oxidative Stress-Induced Cellular Senescence in Neuronal Cells

LRRK2 impairs autophagy by mediating phosphorylation of leucyl‐tRNA synthetase

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