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An early endosome regulator, Rab5b, is an LRRK2 kinase substrate

Journal of biochemistry (Tokyo), 2015-06, Vol.157 (6), p.485-495

2015

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Nuclear α-Synuclein-Derived Cytotoxic Effect via Altered Ribosomal RNA Processing in Primary Mouse Embryonic Fibroblasts

International journal of molecular sciences, 2023-01, Vol.24 (3), p.2132

2023

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Expression of G2019S LRRK2 in Rat Primary Astrocytes Mediates Neurotoxicity and Alters the Dopamine Synthesis Pathway in N27 Cells via Astrocytic Proinflammatory Cytokines and Neurotrophic Factors

Current issues in molecular biology, 2024-05, Vol.46 (5), p.4324-4336

2024

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Expression of transduced nucleolin promotes the clearance of accumulated α-synuclein in rodent cells and animal model

Neurobiology of disease, 2021-07, Vol.154, p.105349, Article 105349

2021

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LRRK2 Inhibition Mitigates the Neuroinflammation Caused by TLR2-Specific α-Synuclein and Alleviates Neuroinflammation-Derived Dopaminergic Neuronal Loss

Cells (Basel, Switzerland), 2022-03, Vol.11 (5), p.861

2022

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Therapeutic Effect of Padina arborescens Extract on a Cell System Model for Parkinson’s Disease

NeuroSci, 2024-09, Vol.5 (3), p.301-314

2024

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G2385R and I2020T Mutations Increase LRRK2 GTPase Activity

BioMed research international, 2016-01, Vol.2016 (2016), p.1-8

2016

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G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses

Animal Cells and Systems, 2019, 23(2), , pp.106-111

2019

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Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease

Parkinson's disease, 2018-01, Vol.2018 (2018), p.1-9

2018

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Effect of leucine-rich repeat kinase 2 (LRRK2) on protein synthesis

Animal Cells and Systems, 2018, 22(1), , pp.15-21

2018

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Analysis of α-synuclein levels related to LRRK2 kinase activity: from substantia nigra to urine of patients with Parkinson's disease

Animal Cells and Systems, 2021, 25(1), , pp.28-36

2021

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Upregulation of the p53-p21 pathway by G2019S LRRK2 contributes to the cellular senescence and accumulation of α-synuclein

Cell cycle (Georgetown, Tex.), 2019-02, Vol.18 (4), p.467-475

2019

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KCHO-1, a novel herbal anti-inflammatory compound, attenuates oxidative stress in an animal model of amyotrophic lateral sclerosis

Journal of Veterinary Science, 2017, 18(4), , pp.487-497

2017

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Mecasin treatment in patients with amyotrophic lateral sclerosis: study protocol for a randomized controlled trial

Trials, 2018-04, Vol.19 (1), p.225-225, Article 225

2018

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Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity

Animal Cells and Systems, 2018, 22(5), , pp.273-280

2018

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Leucine-rich Repeat Kinase 2 (LRRK2) Phosphorylates Rab10 in Glia and Neurons

Biomedical Science Letters, 2019-06, Vol.25 (2), p.177-184

2019

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26-Week Repeated Dose Oral Toxicity Study of KCHO-1 in Sprague-Dawley Rats

Journal of Pharmacopuncture, 2019, 22(3), 71, pp.192-199

2019

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Correction to: Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression

Molecular brain, 2017-10, Vol.10 (1), p.48-48, Article 48

2017

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Characterization of Parkinson's disease-related pathogenic TMEM230 mutants

Animal Cells and Systems, 2018, 22(2), , pp.140-147

2018

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Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression

Molecular brain, 2015-09, Vol.8 (1), Article 54

2015

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Dexamethasone induces the expression of LRRK2 and α-synuclein, two genes that when mutated cause Parkinson's disease in an autosomal dominant manner

BMB Reports, 2013, 46(9), , pp.454-459

2013

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Increased DJ-1 in Urine Exosome of Korean Males with Parkinson’s Disease

BioMed research international, 2014-01, Vol.2014 (2014), p.1-8

2014

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Efficacy of mecasin for treatment of amyotrophic lateral sclerosis: A phase IIa multicenter randomized double-blinded placebo-controlled trial

Journal of ethnopharmacology, 2023-10, Vol.315, p.116670-116670, Article 116670

2023

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A study on the oral toxicity of mecasin in rats

Journal of Pharmacopuncture, 2014, 17(4), 52, pp.61-65

2014

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A 4-week Repeated dose Oral Toxicity Study of Mecasin in Sprague-Dawley Rats to Determine the Appropriate Doses for a 13-week, Repeated Toxicity Test

Journal of Pharmacopuncture, 2015, 18(4), 56, pp.45-50

2015

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An early endosome regulator, Rab5b, is an LRRK2 kinase substrate

Nuclear α-Synuclein-Derived Cytotoxic Effect via Altered Ribosomal RNA Processing in Primary Mouse Embryonic Fibroblasts

Expression of G2019S LRRK2 in Rat Primary Astrocytes Mediates Neurotoxicity and Alters the Dopamine Synthesis Pathway in N27 Cells via Astrocytic Proinflammatory Cytokines and Neurotrophic Factors

Expression of transduced nucleolin promotes the clearance of accumulated α-synuclein in rodent cells and animal model

LRRK2 Inhibition Mitigates the Neuroinflammation Caused by TLR2-Specific α-Synuclein and Alleviates Neuroinflammation-Derived Dopaminergic Neuronal Loss

Therapeutic Effect of Padina arborescens Extract on a Cell System Model for Parkinson’s Disease

G2385R and I2020T Mutations Increase LRRK2 GTPase Activity

G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses

Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease

Effect of leucine-rich repeat kinase 2 (LRRK2) on protein synthesis

Analysis of α-synuclein levels related to LRRK2 kinase activity: from substantia nigra to urine of patients with Parkinson's disease

Upregulation of the p53-p21 pathway by G2019S LRRK2 contributes to the cellular senescence and accumulation of α-synuclein

KCHO-1, a novel herbal anti-inflammatory compound, attenuates oxidative stress in an animal model of amyotrophic lateral sclerosis

Mecasin treatment in patients with amyotrophic lateral sclerosis: study protocol for a randomized controlled trial

Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity

Leucine-rich Repeat Kinase 2 (LRRK2) Phosphorylates Rab10 in Glia and Neurons

26-Week Repeated Dose Oral Toxicity Study of KCHO-1 in Sprague-Dawley Rats

Correction to: Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression

Characterization of Parkinson's disease-related pathogenic TMEM230 mutants

Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression

Dexamethasone induces the expression of LRRK2 and α-synuclein, two genes that when mutated cause Parkinson's disease in an autosomal dominant manner

Increased DJ-1 in Urine Exosome of Korean Males with Parkinson’s Disease

Efficacy of mecasin for treatment of amyotrophic lateral sclerosis: A phase IIa multicenter randomized double-blinded placebo-controlled trial

A study on the oral toxicity of mecasin in rats

A 4-week Repeated dose Oral Toxicity Study of Mecasin in Sprague-Dawley Rats to Determine the Appropriate Doses for a 13-week, Repeated Toxicity Test

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