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Pharmacogenetics of Opioid Response

Clinical pharmacology and therapeutics, 2015-02, Vol.97 (2), p.125-127

2015

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Hyperalgesic responses in methadone maintenance patients

Pain (Amsterdam), 2001-02, Vol.90 (1), p.91-96

2001

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Methadone maintenance patients are cross-tolerant to the antinociceptive effects of morphine

Pain (Amsterdam), 2001-08, Vol.93 (2), p.155-163

2001

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Determination of in vivo absorption, metabolism, and transport of drugs by the human intestinal wall and liver with a novel perfusion technique

Clinical pharmacology and therapeutics, 2001-09, Vol.70 (3), p.217-227

2001

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PharmVar GeneFocus: CYP2B6

Clinical pharmacology and therapeutics, 2021-07, Vol.110 (1), p.82-97

2021

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Opioid activation of toll-like receptor 4 contributes to drug reinforcement

The Journal of neuroscience, 2012-08, Vol.32 (33), p.11187-11200

2012

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Pharmacogenetics of Opioids

Clinical pharmacology and therapeutics, 2007-03, Vol.81 (3), p.429-444

2007

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Acute pain management in opioid-tolerant patients: a growing challenge

Anaesthesia and intensive care, 2011-09, Vol.39 (5), p.804-823

2011

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The effect of acute morphine on obstructive sleep apnoea: a randomised double-blind placebo-controlled crossover trial

Thorax, 2019-02, Vol.74 (2), p.177-184

2019

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Buprenorphine Maintenance Subjects Are Hyperalgesic and Have No Antinociceptive Response to a Very High Morphine Dose

Pain medicine (Malden, Mass.), 2019-01, Vol.20 (1), p.119-128

2019

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Conference report: pharmacogenomics in special populations at WCP2018

British journal of clinical pharmacology, 2019-03, Vol.85 (3), p.467-475

2019

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The influence of CYP2D6 polymorphism and quinidine on the disposition and antitussive effect of dextromethorphan in humans

Clinical pharmacology and therapeutics, 1996-09, Vol.60 (3), p.295-307

1996

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Relationship between 4,5-epoxymorphinan structure and in vitro modulation of cell proliferation

European journal of pharmacology, 2004-06, Vol.494 (2), p.251-262

2004

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Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia

Brain, behavior, and immunity, 2008-11, Vol.22 (8), p.1178-1189

2008

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Effects of Electroacupuncture on Opioid Consumption in Patients with Chronic Musculoskeletal Pain: A Multicenter Randomized Controlled Trial

Pain medicine (Malden, Mass.), 2019-02, Vol.20 (2), p.397-410

2019

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Hyperalgesia in Opioid-Managed Chronic Pain and Opioid-Dependent Patients

The journal of pain, 2009-03, Vol.10 (3), p.316-322

2009

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In vitro opioid induced proliferation of peripheral blood immune cells correlates with in vivo cold pressor pain tolerance in humans: a biological marker of pain tolerance

Pain (Amsterdam), 2004-08, Vol.110 (3), p.751-755

2004

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Pharmacogenomics in Papua New Guineans: unique profiles and implications for enhancing drug efficacy while improving drug safety

Pharmacogenetics and genomics, 2018-06, Vol.28 (6), p.153-164

2018

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Mu receptor binding of some commonly used opioids and their metabolites

Life sciences (1973), 1991, Vol.48 (22), p.2165-2171

1991

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Role of active metabolites in the use of opioids

European journal of clinical pharmacology, 2009-02, Vol.65 (2), p.121-139

2009

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Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors?

BMJ open, 2015-01, Vol.5 (5), p.e006818-e006818

2015

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Inhibition of CYP2D6‐mediated tramadol O‐demethylation in methadone but not buprenorphine maintenance patients

British journal of clinical pharmacology, 2012-11, Vol.74 (5), p.835-841

2012

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Methadone maintenance patients are cross-tolerant to the antinociceptive effects of very high plasma morphine concentrations

Pain (Amsterdam), 2006-02, Vol.120 (3), p.267-275

2006

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Precipitated withdrawal following codeine administration is dependent on CYP genotype

European journal of pharmacology, 2001-08, Vol.425 (3), p.159-164

2001

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CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes

British journal of clinical pharmacology, 2004-03, Vol.57 (3), p.287-297

2004

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Pharmacogenetics of Opioid Response

Hyperalgesic responses in methadone maintenance patients

Methadone maintenance patients are cross-tolerant to the antinociceptive effects of morphine

Determination of in vivo absorption, metabolism, and transport of drugs by the human intestinal wall and liver with a novel perfusion technique

PharmVar GeneFocus: CYP2B6

Opioid activation of toll-like receptor 4 contributes to drug reinforcement

Pharmacogenetics of Opioids

Acute pain management in opioid-tolerant patients: a growing challenge

The effect of acute morphine on obstructive sleep apnoea: a randomised double-blind placebo-controlled crossover trial

Buprenorphine Maintenance Subjects Are Hyperalgesic and Have No Antinociceptive Response to a Very High Morphine Dose

Conference report: pharmacogenomics in special populations at WCP2018

The influence of CYP2D6 polymorphism and quinidine on the disposition and antitussive effect of dextromethorphan in humans

Relationship between 4,5-epoxymorphinan structure and in vitro modulation of cell proliferation

Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia

Effects of Electroacupuncture on Opioid Consumption in Patients with Chronic Musculoskeletal Pain: A Multicenter Randomized Controlled Trial

Hyperalgesia in Opioid-Managed Chronic Pain and Opioid-Dependent Patients

In vitro opioid induced proliferation of peripheral blood immune cells correlates with in vivo cold pressor pain tolerance in humans: a biological marker of pain tolerance

Pharmacogenomics in Papua New Guineans: unique profiles and implications for enhancing drug efficacy while improving drug safety

Mu receptor binding of some commonly used opioids and their metabolites

Role of active metabolites in the use of opioids

Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors?

Inhibition of CYP2D6‐mediated tramadol O‐demethylation in methadone but not buprenorphine maintenance patients

Methadone maintenance patients are cross-tolerant to the antinociceptive effects of very high plasma morphine concentrations

Precipitated withdrawal following codeine administration is dependent on CYP genotype

CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes

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