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Functional Nanoscale Organization of Signaling Molecules Downstream of the T Cell Antigen Receptor

Immunity (Cambridge, Mass.), 2011-11, Vol.35 (5), p.705-720

2011

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Hierarchical nanostructure and synergy of multimolecular signalling complexes

Nature communications, 2016-07, Vol.7 (1), p.12161-13, Article 12161

2016

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miR-155 Controls Lymphoproliferation in LAT Mutant Mice by Restraining T-Cell Apoptosis via SHIP-1/mTOR and PAK1/FOXO3/BIM Pathways

PloS one, 2015-06, Vol.10 (6), p.e0131823-e0131823

2015

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LAT-Independent Erk Activation via Bam32-PLC-γ1-Pak1 Complexes: GTPase-Independent Pak1 Activation

Molecular cell, 2012-10, Vol.48 (2), p.298-312

2012

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Deconstructing Ras Signaling in the Thymus

Molecular and Cellular Biology, 2012-07, Vol.32 (14), p.2748-2759

2012

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Targeted Sos1 deletion reveals its critical role in early T-cell development

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (30), p.12407-12412

2011

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c-Cbl-Mediated Regulation of LAT-Nucleated Signaling Complexes

Molecular and Cellular Biology, 2007-12, Vol.27 (24), p.8622-8636

2007

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Challenges and next steps in the advancement of immunotherapy: summary of the 2018 and 2020 National Cancer Institute workshops on cell-based immunotherapy for solid tumors

Journal for immunotherapy of cancer, 2021-07, Vol.9 (7), p.e003048

2021

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Unexpected Cartilage Phenotype in CD4-Cre-Conditional SOS-Deficient Mice

Frontiers in immunology, 2017-03, Vol.8, p.343-343

2017

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Fine Tuning of TCR Signaling by CD5

The Journal of immunology (1950), 2001-05, Vol.166 (9), p.5464-5472

2001

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miRNA signature of mouse helper T cell hyper-proliferation

PloS one, 2013-06, Vol.8 (6), p.e66709-e66709

2013

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Genetic evidence for the role of Erk activation in a lymphoproliferative disease of mice

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (34), p.14502-14507

2009

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Expression of a TMC6-TMC8-CIB1 heterotrimeric complex in lymphocytes is regulated by each of the components

The Journal of biological chemistry, 2020-11, Vol.295 (47), p.16086-16099

2020

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The LAT story: a tale of cooperativity, coordination, and choreography

Cold Spring Harbor perspectives in biology, 2010-08, Vol.2 (8), p.a005512-a005512

2010

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Report on the 2018 Cancer, Autoimmunity, and Immunology Conference

The Journal of immunology (1950), 2019-05, Vol.202 (10), p.2823-2828

2019

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Absence of both Sos‐1 and Sos‐2 in peripheral CD4+ T cells leads to PI3K pathway activation and defects in migration

European journal of immunology, 2015-08, Vol.45 (8), p.2389-2395

2015

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Bam32: a novel mediator of Erk activation in T cells

International immunology, 2008-07, Vol.20 (7), p.811-818

2008

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Recruitment and activation of PLCγ1 in T cells: a new insight into old domains

The EMBO journal, 2006-02, Vol.25 (4), p.774-784

2006

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Diacylglycerol kinase ζ limits the generation of natural regulatory T cells

Science signaling, 2013-11, Vol.6 (303), p.ra101

2013

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Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps

Molecular biology of the cell, 2008-07, Vol.19 (7), p.2802-2817

2008

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The ability of Sos1 to oligomerize the adaptor protein LAT is separable from its guanine nucleotide exchange activity in vivo

Science signaling, 2013-11, Vol.6 (301), p.ra99

2013

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LAT Is Essential for FcεRI-Mediated Mast Cell Activation

Immunity (Cambridge, Mass.), 2000-05, Vol.12 (5), p.525-535

2000

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A LAT Mutation That Inhibits T Cell Development Yet Induces Lymphoproliferation

Science (American Association for the Advancement of Science), 2002-06, Vol.296 (5575), p.2040-2043

2002

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Essential Role of LAT in T Cell Development

Immunity (Cambridge, Mass.), 1999-03, Vol.10 (3), p.323-332

1999

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A Phospholipase C- gamma 1-Independent, RasGRP1-ERK-Dependent Pathway Drives Lymphoproliferative Disease in Linker for Activation of T Cells-Y136F Mutant Mice

The Journal of immunology (1950), 2013-01, Vol.190 (1), p.147-158

2013

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Functional Nanoscale Organization of Signaling Molecules Downstream of the T Cell Antigen Receptor

Hierarchical nanostructure and synergy of multimolecular signalling complexes

miR-155 Controls Lymphoproliferation in LAT Mutant Mice by Restraining T-Cell Apoptosis via SHIP-1/mTOR and PAK1/FOXO3/BIM Pathways

LAT-Independent Erk Activation via Bam32-PLC-γ1-Pak1 Complexes: GTPase-Independent Pak1 Activation

Deconstructing Ras Signaling in the Thymus

Targeted Sos1 deletion reveals its critical role in early T-cell development

c-Cbl-Mediated Regulation of LAT-Nucleated Signaling Complexes

Challenges and next steps in the advancement of immunotherapy: summary of the 2018 and 2020 National Cancer Institute workshops on cell-based immunotherapy for solid tumors

Unexpected Cartilage Phenotype in CD4-Cre-Conditional SOS-Deficient Mice

Fine Tuning of TCR Signaling by CD5

miRNA signature of mouse helper T cell hyper-proliferation

Genetic evidence for the role of Erk activation in a lymphoproliferative disease of mice

Expression of a TMC6-TMC8-CIB1 heterotrimeric complex in lymphocytes is regulated by each of the components

The LAT story: a tale of cooperativity, coordination, and choreography

Report on the 2018 Cancer, Autoimmunity, and Immunology Conference

Absence of both Sos‐1 and Sos‐2 in peripheral CD4+ T cells leads to PI3K pathway activation and defects in migration

Bam32: a novel mediator of Erk activation in T cells

Recruitment and activation of PLCγ1 in T cells: a new insight into old domains

Diacylglycerol kinase ζ limits the generation of natural regulatory T cells

Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps

The ability of Sos1 to oligomerize the adaptor protein LAT is separable from its guanine nucleotide exchange activity in vivo

LAT Is Essential for FcεRI-Mediated Mast Cell Activation

A LAT Mutation That Inhibits T Cell Development Yet Induces Lymphoproliferation

Essential Role of LAT in T Cell Development

A Phospholipase C- gamma 1-Independent, RasGRP1-ERK-Dependent Pathway Drives Lymphoproliferative Disease in Linker for Activation of T Cells-Y136F Mutant Mice

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