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Analysis of ROR1 Protein Expression in Human Cancer and Normal Tissues

Clinical cancer research, 2017-06, Vol.23 (12), p.3061-3071

2017

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safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer

Proceedings of the National Academy of Sciences - PNAS, 2008-01, Vol.105 (2), p.623-628

2008

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T-Cells Expressing a Highly Potent PRAME-Specific T-Cell Receptor in Combination with a Chimeric PD1-41BB Co-Stimulatory Receptor Show a Favorable Preclinical Safety Profile and Strong Anti-Tumor Reactivity

Cancers, 2022-04, Vol.14 (8), p.1998

2022

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Minimal amino acid exchange in human TCR constant regions fosters improved function of TCR gene-modified T cells

The Journal of immunology (1950), 2010-06, Vol.184 (11), p.6223-6231

2010

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Development of a CD8 co-receptor independent T-cell receptor specific for tumor-associated antigen MAGE-A4 for next generation T-cell-based immunotherapy

Journal for immunotherapy of cancer, 2021-03, Vol.9 (3), p.e002035

2021

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427 Development of iPSC-derived cytotoxic CD8+ T-cells as the basis for innovative off-the-shelf cancer immunotherapies

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A477-A477

2023

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1515 Gene edited iPSC-derived macrophages (iMACs) show increased phagocytosis in pre-clinical tumor models

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 2), p.A1740-A1740

2023

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Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo

Leukemia, 2016-02, Vol.30 (2), p.492-500

2016

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614 Co-stimulation via PD1–41BB chimeric switch receptor enhances function of TCR-T cells in an immune-suppressive milieu and under chronic antigen stimulation

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A650-A650

2020

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Fully human CD19-specific chimeric antigen receptors for T-cell therapy

Leukemia, 2017-10, Vol.31 (10), p.2191-2199

2017

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161 Development of a CD8 co-receptor independent T cell receptor specific for tumor-associated antigen MAGE-A4 for next generation T cell-based immunotherapy

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A97-A97

2020

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CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients

The Journal of clinical investigation, 2016-06, Vol.126 (6), p.2123-2138

2016

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Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells

Clinical cancer research, 2013-06, Vol.19 (12), p.3153-3164

2013

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Inclusion of Strep-tag II in design of antigen receptors for T-cell immunotherapy

Nature biotechnology, 2016-04, Vol.34 (4), p.430-434

2016

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Tumour ischaemia by interferon-γ resembles physiological blood vessel regression

Nature (London), 2017-05, Vol.545 (7652), p.98-102

2017

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Targeted antibody-mediated depletion of murine CD19 CAR T cells permanently reverses B cell aplasia

The Journal of clinical investigation, 2016-11, Vol.126 (11), p.4262-4272

2016

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Development of T-cell immunotherapy for hematopoietic stem cell transplantation recipients at risk of leukemia relapse

Blood, 2018-01, Vol.131 (1), p.108-120

2018

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Role of memory T cell subsets for adoptive immunotherapy

Seminars in immunology, 2016-02, Vol.28 (1), p.28-34

2016

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The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity

Cancer immunology research, 2015-02, Vol.3 (2), p.125-135

2015

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Abstract 1520: Targetable immunogenic tumor specific antigens can be identified in non-coding regions of the genome

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1520-1520

2021

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Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function

Science signaling, 2021-08, Vol.14 (697)

2021

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Misinitiation of intrathymic MART‐1 transcription and biased TCR usage explain the high frequency of MART‐1‐specific T cells

European journal of immunology, 2014-09, Vol.44 (9), p.2811-2821

2014

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Safety of targeting ROR1 in primates with chimeric antigen receptor-modified T cells

Cancer immunology research, 2015-02, Vol.3 (2), p.206-216

2015

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Abstract 1521: Combining a PRAME-specific TCR showing potent in vitro and in vivo anti-tumor reactivity and a favorable preclinical safety profile with a PD1-41BB switch receptor results in highly efficient T cells

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1521-1521

2021

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Adoptive therapy with chimeric antigen receptor-modified T cells of defined subset composition

The cancer journal (Sudbury, Mass.), 2014-03, Vol.20 (2), p.141

2014

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Analysis of ROR1 Protein Expression in Human Cancer and Normal Tissues

safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer

T-Cells Expressing a Highly Potent PRAME-Specific T-Cell Receptor in Combination with a Chimeric PD1-41BB Co-Stimulatory Receptor Show a Favorable Preclinical Safety Profile and Strong Anti-Tumor Reactivity

Minimal amino acid exchange in human TCR constant regions fosters improved function of TCR gene-modified T cells

Development of a CD8 co-receptor independent T-cell receptor specific for tumor-associated antigen MAGE-A4 for next generation T-cell-based immunotherapy

427 Development of iPSC-derived cytotoxic CD8+ T-cells as the basis for innovative off-the-shelf cancer immunotherapies

1515 Gene edited iPSC-derived macrophages (iMACs) show increased phagocytosis in pre-clinical tumor models

Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo

614 Co-stimulation via PD1–41BB chimeric switch receptor enhances function of TCR-T cells in an immune-suppressive milieu and under chronic antigen stimulation

Fully human CD19-specific chimeric antigen receptors for T-cell therapy

161 Development of a CD8 co-receptor independent T cell receptor specific for tumor-associated antigen MAGE-A4 for next generation T cell-based immunotherapy

CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients

Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells

Inclusion of Strep-tag II in design of antigen receptors for T-cell immunotherapy

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression

Targeted antibody-mediated depletion of murine CD19 CAR T cells permanently reverses B cell aplasia

Development of T-cell immunotherapy for hematopoietic stem cell transplantation recipients at risk of leukemia relapse

Role of memory T cell subsets for adoptive immunotherapy

The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity

Abstract 1520: Targetable immunogenic tumor specific antigens can be identified in non-coding regions of the genome

Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function

Misinitiation of intrathymic MART‐1 transcription and biased TCR usage explain the high frequency of MART‐1‐specific T cells

Safety of targeting ROR1 in primates with chimeric antigen receptor-modified T cells

Abstract 1521: Combining a PRAME-specific TCR showing potent in vitro and in vivo anti-tumor reactivity and a favorable preclinical safety profile with a PD1-41BB switch receptor results in highly efficient T cells

Adoptive therapy with chimeric antigen receptor-modified T cells of defined subset composition

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