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Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

Molecular and Cellular Biology, 1995-11, Vol.15 (11), p.6443-6453

1995

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P21ras is Modified by a Farnesyl Isoprenoid

Proceedings of the National Academy of Sciences - PNAS, 1989-11, Vol.86 (21), p.8323-8327

1989

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Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

Molecular and Cellular Biology, 1996-07, Vol.16 (7), p.3923-3933

1996

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Farnesol Modification of Kirsten-Ras Exon 4B Protein is Essential for Transformation

Proceedings of the National Academy of Sciences - PNAS, 1990-04, Vol.87 (8), p.3042-3046

1990

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Cellular functions of TC10, a rho family GTPase : regulation of morphology, signal transduction and cell growth

Oncogene, 1999-07, Vol.18 (26), p.3831-3845

1999

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Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras

Molecular and Cellular Biology, 1994-10, Vol.14 (10), p.6848-6857

1994

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Guanosine 5'-O-(thiotriphosphate)-dependent inositol trisphosphate formation in membranes is inhibited by phorbol ester and protein kinase C

The Journal of biological chemistry, 1987-02, Vol.262 (4), p.1638-1643

1987

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Phorbol ester inhibits phosphoinositide hydrolysis and calcium mobilization in cultured astrocytoma cells

The Journal of biological chemistry, 1985-05, Vol.260 (9), p.5236-5239

1985

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The COOH-terminal domain of the Rap1A (Krev-1) protein is isoprenylated and supports transformation by an H-Ras:Rap1A chimeric protein

Molecular and Cellular Biology, 1991-03, Vol.11 (3), p.1523-1530

1991

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The Mitogen-activated Protein Kinase Phosphatases PAC1, MKP-1, and MKP-2 Have Unique Substrate Specificities and Reduced Activity in Vivo toward the ERK2 sevenmaker Mutation

The Journal of biological chemistry, 1996-03, Vol.271 (11), p.6497-6501

1996

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Requirement For C-terminal Sequences in Regulation of Ect2 Guanine Nucleotide Exchange Specificity and Transformation

The Journal of biological chemistry, 2004-06, Vol.279 (24), p.25226-25233

2004

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Critical role of Rho in cell transformation by oncogenic Ras

Oncogene, 1995-06, Vol.10 (12), p.2289-2296

1995

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Guanine nucleotide exchange factors: Activators of Ras superfamily proteins

Molecular reproduction and development, 1995-12, Vol.42 (4), p.468-476

1995

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Oncogenic Neu/ErbB-2 increases Ets, AP-1, and NF- Kappa B-dependent gene expression, and inhibiting Ets activation blocks Neu-mediated cellular transformation

The Journal of biological chemistry, 1996-04, Vol.271 (14), p.7992-7998

1996

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ROCK-Generated Contractility Regulates Breast Epithelial Cell Differentiation in Response to the Physical Properties of a Three-Dimensional Collagen Matrix

The Journal of cell biology, 2003-11, Vol.163 (3), p.583-595

2003

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A Non-farnesylated Ha-Ras Protein Can Be Palmitoylated and Trigger Potent Differentiation and Transformation

The Journal of biological chemistry, 1999-01, Vol.274 (3), p.1423-1431

1999

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Functional Analysis of Protein N-Myristoylation: Metabolic Labeling Studies Using Three Oxygen-Substituted Analogs of Myristic Acid and Cultured Mammalian Cells Provide Evidence for Protein-Sequence-Specific Incorporation and Analog-Specific Redistribution

Proceedings of the National Academy of Sciences - PNAS, 1990-11, Vol.87 (21), p.8511-8515

1990

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Novel determinants of H-Ras plasma membrane localization and transformation

Oncogene, 1996-11, Vol.13 (9), p.1901-1909

1996

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Modulation of HIV-1 Replication by a Novel RhoA Effector Activity

The Journal of immunology (1950), 2000-05, Vol.164 (10), p.5369-5374

2000

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The carboxyl-terminal CXXX sequence of Gi alpha, but not Rab5 or Rab11, supports Ras processing and transforming activity

The Journal of biological chemistry, 1993-06, Vol.268 (16), p.11548-11552

1993

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Receptor-mediated inositol phosphate formation in relation to calcium mobilization: a comparison of two cell lines

Molecular pharmacology, 1987-09, Vol.32 (3), p.376-383

1987

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The ect2 rho Guanine nucleotide exchange factor is essential for early mouse development and normal cell cytokinesis and migration

Genes & cancer, 2011-10, Vol.2 (10), p.932-942

2011

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Activation of the Cellular Proto-Oncogene Product p21Ras by Addition of a Myristylation Signal

Science (American Association for the Advancement of Science), 1989-03, Vol.243 (4898), p.1600-1603

1989

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Analyses of transforming activity of rho family activators

Methods in Enzymology, 2000, Vol.325, p.425-441

2000

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The six amino-terminal amino acids of p60src are sufficient to cause myristylation of p21v-ras

Molecular and Cellular Biology, 1988-09, Vol.8 (9), p.3960-3963

1988

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Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

P21ras is Modified by a Farnesyl Isoprenoid

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

Farnesol Modification of Kirsten-Ras Exon 4B Protein is Essential for Transformation

Cellular functions of TC10, a rho family GTPase : regulation of morphology, signal transduction and cell growth

Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras

Guanosine 5'-O-(thiotriphosphate)-dependent inositol trisphosphate formation in membranes is inhibited by phorbol ester and protein kinase C

Phorbol ester inhibits phosphoinositide hydrolysis and calcium mobilization in cultured astrocytoma cells

The COOH-terminal domain of the Rap1A (Krev-1) protein is isoprenylated and supports transformation by an H-Ras:Rap1A chimeric protein

The Mitogen-activated Protein Kinase Phosphatases PAC1, MKP-1, and MKP-2 Have Unique Substrate Specificities and Reduced Activity in Vivo toward the ERK2 sevenmaker Mutation

Requirement For C-terminal Sequences in Regulation of Ect2 Guanine Nucleotide Exchange Specificity and Transformation

Critical role of Rho in cell transformation by oncogenic Ras

Guanine nucleotide exchange factors: Activators of Ras superfamily proteins

Oncogenic Neu/ErbB-2 increases Ets, AP-1, and NF- Kappa B-dependent gene expression, and inhibiting Ets activation blocks Neu-mediated cellular transformation

ROCK-Generated Contractility Regulates Breast Epithelial Cell Differentiation in Response to the Physical Properties of a Three-Dimensional Collagen Matrix

A Non-farnesylated Ha-Ras Protein Can Be Palmitoylated and Trigger Potent Differentiation and Transformation

Functional Analysis of Protein N-Myristoylation: Metabolic Labeling Studies Using Three Oxygen-Substituted Analogs of Myristic Acid and Cultured Mammalian Cells Provide Evidence for Protein-Sequence-Specific Incorporation and Analog-Specific Redistribution

Novel determinants of H-Ras plasma membrane localization and transformation

Modulation of HIV-1 Replication by a Novel RhoA Effector Activity

The carboxyl-terminal CXXX sequence of Gi alpha, but not Rab5 or Rab11, supports Ras processing and transforming activity

Receptor-mediated inositol phosphate formation in relation to calcium mobilization: a comparison of two cell lines

The ect2 rho Guanine nucleotide exchange factor is essential for early mouse development and normal cell cytokinesis and migration

Activation of the Cellular Proto-Oncogene Product p21Ras by Addition of a Myristylation Signal

Analyses of transforming activity of rho family activators

The six amino-terminal amino acids of p60src are sufficient to cause myristylation of p21v-ras

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