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Fluorine‐Containing Drugs Approved by the FDA in 2018

Chemistry : a European journal, 2019-09, Vol.25 (51), p.11797-11819

2019

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Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

Chemical reviews, 2016-01, Vol.116 (2), p.422-518

2016

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Modern Approaches for Asymmetric Construction of Carbon–Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs

Chemical reviews, 2018-04, Vol.118 (7), p.3887-3964

2018

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Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

Chemical reviews, 2014-02, Vol.114 (4), p.2432-2506

2014

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Evolution and Future of Hetero‐ and Hydro‐Trifluoromethylations of Unsaturated C−C Bonds

Advanced synthesis & catalysis, 2023-02, Vol.365 (4), p.398-462

2023

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Next generation organofluorine containing blockbuster drugs

Journal of fluorine chemistry, 2020-11, Vol.239, p.109639, Article 109639

2020

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Applications of fluorine-containing amino acids for drug design

European journal of medicinal chemistry, 2020-01, Vol.186, p.111826-111826, Article 111826

2020

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Tailor‐Made Amino Acids and Fluorinated Motifs as Prominent Traits in Modern Pharmaceuticals

Chemistry : a European journal, 2020-09, Vol.26 (50), p.11349-11390

2020

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Assembly of Fluorinated Quaternary Stereogenic Centers through Catalytic Enantioselective Detrifluoroacetylative Aldol Reactions

Angewandte Chemie International Edition, 2015-05, Vol.54 (20), p.6019-6023

International ed. in English, 2015

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The self-disproportionation of enantiomers (SDE): a menace or an opportunity?

Chemical science (Cambridge), 2018-02, Vol.9 (7), p.1718-1739

2018

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N-tert-Butylsulfinyl-3,3,3-trifluoroacetaldimine: Versatile Reagent for Asymmetric Synthesis of Trifluoromethyl-Containing Amines and Amino Acids of Pharmaceutical Importance

European journal of organic chemistry, 2016-12, Vol.2016 (36), p.5917-5932

2016

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Biological evaluation of both enantiomers of fluoro-thalidomide using human myeloma cell line H929 and others

PloS one, 2017-08, Vol.12 (8), p.e0182152

2017

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New Approved Drugs Appearing in the Pharmaceutical Market in 2022 Featuring Fragments of Tailor-Made Amino Acids and Fluorine

Molecules (Basel, Switzerland), 2023-04, Vol.28 (9), p.3651

2023

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Recommended Tests for the Self-Disproportionation of Enantiomers (SDE) to Ensure Accurate Reporting of the Stereochemical Outcome of Enantioselective Reactions

Molecules (Basel, Switzerland), 2021-05, Vol.26 (9), p.2757

2021

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Remarkable Amplification of the Self-Disproportionation of Enantiomers on Achiral-Phase Chromatography Columns

Angewandte Chemie International Edition, 2006-01, Vol.45 (5), p.766-769

Soloshonok, Vadim A.

2006

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A Call for a Change in Policy Regarding the Necessity for SDE Tests to Validate the Veracity of the Outcome of Enantioselective Syntheses, the Inherent Chiral State of Natural Products, and Other Cases Involving Enantioenriched Samples

Molecules (Basel, Switzerland), 2021-06, Vol.26 (13), p.3994

2021

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Self-disproportionation of enantiomers via achiral chromatography: a warning and an extra dimension in optical purifications

Chemical Society reviews, 2012-01, Vol.41 (11), p.418-4188

2012

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The self‐disproportionation of enantiomers (SDE): The effect of scaling down, potential problems versus prospective applications, possible new occurrences, and unrealized opportunities?

Electrophoresis, 2019-08, Vol.40 (15), p.1869-1880

2019

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Asymmetric Michael Addition in Synthesis of β-Substituted GABA Derivatives

Molecules (Basel, Switzerland), 2022-06, Vol.27 (12), p.3797

2022

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Organocatalytic Enantioselective Nucleophilic Alkynylation of Allyl Fluorides Affording Chiral Skipped Ene-ynes

Angewandte Chemie International Edition, 2016-06, Vol.55 (23), p.6744-6748

International ed. in English, 2016

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The Latest FDA-Approved Pharmaceuticals Containing Fragments of Tailor-Made Amino Acids and Fluorine

Pharmaceuticals (Basel, Switzerland), 2022-08, Vol.15 (8), p.999

2022

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Successful trifluoromethoxy-containing pharmaceuticals and agrochemicals

Journal of fluorine chemistry, 2022-05, Vol.257-258, p.109978, Article 109978

2022

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Detrifluoroacetylative in Situ Generation of Free 3‑Fluoroindolin-2-one-Derived Tertiary Enolates: Design, Synthesis, and Assessment of Reactivity toward Asymmetric Mannich Reactions

Organic letters, 2016-07, Vol.18 (13), p.3270-3273

2016

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Asymmetric Synthesis of Tailor-Made Amino Acids Using Chiral Ni(II) Complexes of Schiff Bases. An Update of the Recent Literature

Molecules (Basel, Switzerland), 2020-06, Vol.25 (12), p.2739

2020

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Asymmetric Synthesis of Cyclic Fluorinated Amino Acids

European journal of organic chemistry, 2018-08, Vol.2018 (27-28), p.3688-3692

2018

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Fluorine‐Containing Drugs Approved by the FDA in 2018

Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

Modern Approaches for Asymmetric Construction of Carbon–Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

Evolution and Future of Hetero‐ and Hydro‐Trifluoromethylations of Unsaturated C−C Bonds

Next generation organofluorine containing blockbuster drugs

Applications of fluorine-containing amino acids for drug design

Tailor‐Made Amino Acids and Fluorinated Motifs as Prominent Traits in Modern Pharmaceuticals

Assembly of Fluorinated Quaternary Stereogenic Centers through Catalytic Enantioselective Detrifluoroacetylative Aldol Reactions

The self-disproportionation of enantiomers (SDE): a menace or an opportunity?

N-tert-Butylsulfinyl-3,3,3-trifluoroacetaldimine: Versatile Reagent for Asymmetric Synthesis of Trifluoromethyl-Containing Amines and Amino Acids of Pharmaceutical Importance

Biological evaluation of both enantiomers of fluoro-thalidomide using human myeloma cell line H929 and others

New Approved Drugs Appearing in the Pharmaceutical Market in 2022 Featuring Fragments of Tailor-Made Amino Acids and Fluorine

Recommended Tests for the Self-Disproportionation of Enantiomers (SDE) to Ensure Accurate Reporting of the Stereochemical Outcome of Enantioselective Reactions

Remarkable Amplification of the Self-Disproportionation of Enantiomers on Achiral-Phase Chromatography Columns

A Call for a Change in Policy Regarding the Necessity for SDE Tests to Validate the Veracity of the Outcome of Enantioselective Syntheses, the Inherent Chiral State of Natural Products, and Other Cases Involving Enantioenriched Samples

Self-disproportionation of enantiomers via achiral chromatography: a warning and an extra dimension in optical purifications

The self‐disproportionation of enantiomers (SDE): The effect of scaling down, potential problems versus prospective applications, possible new occurrences, and unrealized opportunities?

Asymmetric Michael Addition in Synthesis of β-Substituted GABA Derivatives

Organocatalytic Enantioselective Nucleophilic Alkynylation of Allyl Fluorides Affording Chiral Skipped Ene-ynes

The Latest FDA-Approved Pharmaceuticals Containing Fragments of Tailor-Made Amino Acids and Fluorine

Successful trifluoromethoxy-containing pharmaceuticals and agrochemicals

Detrifluoroacetylative in Situ Generation of Free 3‑Fluoroindolin-2-one-Derived Tertiary Enolates: Design, Synthesis, and Assessment of Reactivity toward Asymmetric Mannich Reactions

Asymmetric Synthesis of Tailor-Made Amino Acids Using Chiral Ni(II) Complexes of Schiff Bases. An Update of the Recent Literature

Asymmetric Synthesis of Cyclic Fluorinated Amino Acids

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