UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 45

Sortiert nach

Use of Radioactive Compounds and Autoradiography to Determine Drug Tissue Distribution

Chemical research in toxicology, 2012-03, Vol.25 (3), p.543-555

Solon, Eric G

2012

Volltextzugriff (PDF)

Autoradiography techniques and quantification of drug distribution

Cell and tissue research, 2015-04, Vol.360 (1), p.87-107

Solon, Eric G

2015

Volltextzugriff (PDF)

Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development

The AAPS journal, 2010-03, Vol.12 (1), p.11-26

2010

Volltextzugriff (PDF)

Imaging Mass Spectrometry (IMS) for drug discovery and development survey: Results on methods, applications and regulatory compliance

Drug metabolism and pharmacokinetics, 2022-04, Vol.43, p.100438-100438, Article 100438

2022

Volltextzugriff (PDF)

Autoradiography: high-resolution molecular imaging in pharmaceutical discovery and development

Expert opinion on drug discovery, 2007-04, Vol.2 (4), p.503-514

Solon, Eric G

2007

Volltextzugriff (PDF)

Distribution of Radioactivity in Bone and Related Structures following Administration of [14C]Dalbavancin to New Zealand White Rabbits

Antimicrobial Agents and Chemotherapy, 2007-08, Vol.51 (8), p.3008-3010

2007

Volltextzugriff (PDF)

Increased Hepatobiliary Clearance of Unconjugated Thyroxine Determines DMP 904-Induced Alterations in Thyroid Hormone Homeostasis in Rats

Toxicological sciences, 2005-04, Vol.84 (2), p.232-242

2005

Volltextzugriff (PDF)

Quantitative whole-body autoradiography in the pharmaceutical industry: Survey results on study design, methods, and regulatory compliance

Journal of pharmacological and toxicological methods, 2001-09, Vol.46 (2), p.73-81

2001

Volltextzugriff (PDF)

Concurrent induction and mechanism-based inactivation of CYP3A4 by an L-valinamide derivative

Drug metabolism and disposition, 2003-09, Vol.31 (9), p.1170

2003

Volltextzugriff (PDF)

Role of P-glycoprotein and the intestine in the excretion of DPC 333 [(2R)-2-{(3R)-3-amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in rodents

Drug metabolism and disposition, 2008-06, Vol.36 (6), p.1102

2008

Volltextzugriff (PDF)

Abstract 2321: SGI-110 SQ provides superior disposition profile for active metabolite decitabine than decitabine IV infusion: Results from mass balance and tissue distribution study in cynomolgus monkeys and in vitro human studies

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.2321-2321

2014

Volltextzugriff (PDF)

Characterization of Antineovascularization Activity and Ocular Pharmacokinetics of Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitor GNE-947

Drug metabolism and disposition, 2020-05, Vol.48 (5), p.408-419

2020

Volltextzugriff (PDF)

Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo

Antiviral research, 2018-02, Vol.150, p.112-122

2018

Volltextzugriff (PDF)

Pharmacokinetics and distribution of 2‐hydroxypropyl‐β‐cyclodextrin following a single intrathecal dose to cats

Journal of inherited metabolic disease, 2020-05, Vol.43 (3), p.618-634

2020

Volltextzugriff (PDF)

Pharmacokinetics, distribution, metabolism, and excretion of the dual reuptake inhibitor [14C]-nefopam in rats

Xenobiotica, 2016-11, Vol.46 (11), p.1026-1048

2016

Volltextzugriff (PDF)

Interaction of ritonavir on tissue distribution of a [(14)c]L-valinamide, a potent human immunodeficiency virus-1 protease inhibitor, in rats using quantitative whole-body autoradiography

Drug metabolism and disposition, 2002-11, Vol.30 (11), p.1164

2002

Volltextzugriff (PDF)

Quantitative Tissue Distribution and Pharmacokinetics of IW‐1973, a Novel Clinical‐Stage sGC Stimulator, After Oral Administration in Rats

The FASEB journal, 2017-04, Vol.31 (S1)

2017

Volltextzugriff (PDF)

10th international symposium on the synthesis and applications of isotopes and isotopically labelled compounds-WBA-drug discovery and development Session 12, Tuesday, June 16, 2009

Journal of labelled compounds & radiopharmaceuticals, 2010-05, Vol.53 (5-6), p.330-331

2010

Volltextzugriff (PDF)

Peginesatide clearance, distribution, metabolism, and excretion in monkeys following intravenous administration

Drug metabolism and disposition, 2013-04, Vol.41 (4), p.774

2013

Volltextzugriff (PDF)

Excretion mass balance and quantitative whole‐body autoradiography following a single oral (PO) administration of [14C]MSDC 0602, an mTOT‐modulating insulin sensitizer, in Sprague Dawley (SD) and Long‐Evans (LE) rats

The FASEB journal, 2012-04, Vol.26 (S1)

2012

Volltextzugriff (PDF)

Erratum to: Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development

The AAPS journal, 2010-03, Vol.12 (1), p.107-107

2010

Volltextzugriff (PDF)

Absorption, distribution, metabolism, and excretion of [¹⁴C]GDC-0449 (vismodegib), an orally active hedgehog pathway inhibitor, in rats and dogs: a unique metabolic pathway via pyridine ring opening

Drug metabolism and disposition, 2011-06, Vol.39 (6), p.952

2011

Volltextzugriff (PDF)

Continued discussion of “Quantitative whole-body autoradiography in the pharmaceutical industry. Survey results on study design, methods and regulatory compliance” (Solon, 2002; Stumpf, 2002a,b)

Journal of pharmacological and toxicological methods, 2002-11, Vol.48 (3), p.187-189

Solon, Eric

2002

Volltextzugriff (PDF)

10th International symposium on the synthesis and applications of Isotopes and Isotopically labelled compounds

Journal of labelled compounds & radiopharmaceuticals, 2010-05, Vol.53 (5-6), p.225-226

2010

Volltextzugriff (PDF)

Evaluation of metabolism and disposition of GDC-0152 in rats using 14C labeling strategy at two different positions: a novel formation of hippuric acid from 4-phenyl-5-amino-1,2,3-thiadiazole

Drug metabolism and disposition, 2013-02, Vol.41 (2), p.508

2013

Volltextzugriff (PDF)

1 – 25 von 45

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(40)
Mit Volltextzugriff
(36)

Publikationsform

Sprache

Englisch
(45)
Japanisch
(6)

Erscheinungsjahr

n.n

Thema

Science & Technology
(28)
Life Sciences & Biomedicine
(24)
Animals
(20)
Pharmacology & Pharmacy
(15)
Male
(14)
Tissue Distribution
(13)
Humans
(11)
Female
(9)
Biological And Medical Sciences
(8)
Medical Sciences
(8)
Rats
(8)
Autoradiography
(7)
Rats, Sprague-Dawley
(7)
Pharmacology. Drug Treatments
(6)
Toxicology
(6)
Adme
(5)
Pharmacokinetics
(5)
Autoradiography - Methods
(4)
Cytochrome P-450 Enzyme System - Metabolism
(4)
Physical Sciences
(4)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Use of Radioactive Compounds and Autoradiography to Determine Drug Tissue Distribution

Autoradiography techniques and quantification of drug distribution

Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development

Imaging Mass Spectrometry (IMS) for drug discovery and development survey: Results on methods, applications and regulatory compliance

Autoradiography: high-resolution molecular imaging in pharmaceutical discovery and development

Distribution of Radioactivity in Bone and Related Structures following Administration of [14C]Dalbavancin to New Zealand White Rabbits

Increased Hepatobiliary Clearance of Unconjugated Thyroxine Determines DMP 904-Induced Alterations in Thyroid Hormone Homeostasis in Rats

Quantitative whole-body autoradiography in the pharmaceutical industry: Survey results on study design, methods, and regulatory compliance

Concurrent induction and mechanism-based inactivation of CYP3A4 by an L-valinamide derivative

Role of P-glycoprotein and the intestine in the excretion of DPC 333 [(2R)-2-{(3R)-3-amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in rodents

Abstract 2321: SGI-110 SQ provides superior disposition profile for active metabolite decitabine than decitabine IV infusion: Results from mass balance and tissue distribution study in cynomolgus monkeys and in vitro human studies

Characterization of Antineovascularization Activity and Ocular Pharmacokinetics of Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitor GNE-947

Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo

Pharmacokinetics and distribution of 2‐hydroxypropyl‐β‐cyclodextrin following a single intrathecal dose to cats

Pharmacokinetics, distribution, metabolism, and excretion of the dual reuptake inhibitor [14C]-nefopam in rats

Interaction of ritonavir on tissue distribution of a [(14)c]L-valinamide, a potent human immunodeficiency virus-1 protease inhibitor, in rats using quantitative whole-body autoradiography

Quantitative Tissue Distribution and Pharmacokinetics of IW‐1973, a Novel Clinical‐Stage sGC Stimulator, After Oral Administration in Rats

10th international symposium on the synthesis and applications of isotopes and isotopically labelled compounds-WBA-drug discovery and development Session 12, Tuesday, June 16, 2009

Peginesatide clearance, distribution, metabolism, and excretion in monkeys following intravenous administration

Excretion mass balance and quantitative whole‐body autoradiography following a single oral (PO) administration of [14C]MSDC 0602, an mTOT‐modulating insulin sensitizer, in Sprague Dawley (SD) and Long‐Evans (LE) rats

Erratum to: Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development

Absorption, distribution, metabolism, and excretion of [¹⁴C]GDC-0449 (vismodegib), an orally active hedgehog pathway inhibitor, in rats and dogs: a unique metabolic pathway via pyridine ring opening

Continued discussion of “Quantitative whole-body autoradiography in the pharmaceutical industry. Survey results on study design, methods and regulatory compliance” (Solon, 2002; Stumpf, 2002a,b)

10th International symposium on the synthesis and applications of Isotopes and Isotopically labelled compounds

Evaluation of metabolism and disposition of GDC-0152 in rats using 14C labeling strategy at two different positions: a novel formation of hippuric acid from 4-phenyl-5-amino-1,2,3-thiadiazole

Suchergebnisse filtern