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Connexin43 phosphorylation: structural changes and biological effects

Biochemical journal, 2009-04, Vol.419 (2), p.261-272

2009

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Specific Cx43 phosphorylation events regulate gap junction turnover in vivo

FEBS letters, 2014-04, Vol.588 (8), p.1423-1429

2014

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Spatio-temporal regulation of connexin43 phosphorylation and gap junction dynamics

Biochimica et biophysica acta. Biomembranes, 2018-01, Vol.1860 (1), p.83-90

2018

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Kinase programs spatiotemporally regulate gap junction assembly and disassembly: Effects on wound repair

Seminars in cell & developmental biology, 2016-02, Vol.50, p.40-48

2016

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Cx43 phosphorylation–mediated effects on ERK and Akt protect against ischemia reperfusion injury and alter the stability of the stress-inducible protein NDRG1

The Journal of biological chemistry, 2019-08, Vol.294 (31), p.11762-11771

2019

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Src Regulation of Cx43 Phosphorylation and Gap Junction Turnover

Biomolecules (Basel, Switzerland), 2020-11, Vol.10 (12), p.1596

2020

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Cx43 phosphorylation sites regulate pancreatic cancer metastasis

Oncogene, 2021-03, Vol.40 (10), p.1909-1920

2021

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Connexin43 phosphorylation in brain, cardiac, endothelial and epithelial tissues

Biochimica et biophysica acta, 2012-08, Vol.1818 (8), p.1985-1992

2012

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Connexin phosphorylation as a regulatory event linked to gap junction channel assembly

Biochimica et biophysica acta, 2005-06, Vol.1711 (2), p.154-163

2005

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Phosphorylation of connexin 43 at MAPK, PKC or CK1 sites each distinctly alter the kinetics of epidermal wound repair

Journal of cell science, 2019-09, Vol.132 (18)

2019

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Regulation of Cx37 channel and growth-suppressive properties by phosphorylation

Journal of cell science, 2017-10, Vol.130 (19), p.3308-3321

2017

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Key connexin 43 phosphorylation events regulate the gap junction life cycle

The Journal of membrane biology, 2007-06, Vol.217 (1-3), p.35-41

2007

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The lipidated connexin mimetic peptide SRPTEKT- Hdc is a potent inhibitor of Cx43 channels with specificity for the pS368 phospho-isoform

American Journal of Physiology: Cell Physiology, 2019-10, Vol.317 (4), p.C825-C842

2019

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CD133 as a Biomarker for an Autoantibody-to-ImmunoPET Paradigm for the Early Detection of Small Cell Lung Cancer

Journal of Nuclear Medicine, 2022-11, Vol.63 (11), p.1701-1707

2022

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Posttranslational modifications induce autoantibodies with risk prediction capability in patients with small cell lung cancer

Science translational medicine, 2023-01, Vol.15 (678), p.eadd8469

2023

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Casein Kinase 1 Phosphomimetic Mutations Negatively Impact Connexin-43 Gap Junctions in Human Pluripotent Stem Cell-Derived Cardiomyocytes

Biomolecules (Basel, Switzerland), 2024-01, Vol.14 (1), p.61

2024

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Optical mapping of human embryonic stem cell-derived cardiomyocyte graft electrical activity in injured hearts

Stem cell research & therapy, 2020-09, Vol.11 (1), p.417-417, Article 417

2020

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Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC

The Journal of cell biology, 2007-12, Vol.179 (6), p.1301-1309

2007

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Trafficking and Recycling of the Connexin43 Gap Junction Protein during Mitosis

Traffic (Copenhagen, Denmark), 2010-11, Vol.11 (11), p.1471-1486

2010

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The C-terminus of connexin43 adopts different conformations in the Golgi and gap junction as detected with structure-specific antibodies

Biochemical journal, 2007-12, Vol.408 (3), p.375-385

2007

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Connexin 43 Interacts with Zona Occludens-1 and -2 Proteins in a Cell Cycle Stage-specific Manner

The Journal of biological chemistry, 2005-08, Vol.280 (34), p.30416-30421

2005

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CASK (LIN2) interacts with Cx43 in wounded skin and their coexpression affects cell migration

Journal of cell science, 2012-02, Vol.125 (Pt 3), p.695-702

2012

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Spatiotemporal Proteomic Analyses during Pancreas Cancer Progression Identifies Serine/Threonine Stress Kinase 4 (STK4) as a Novel Candidate Biomarker for Early Stage Disease

Molecular & cellular proteomics, 2014-12, Vol.13 (12), p.3484-3496

2014

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Correction to: Optical mapping of human embryonic stem cell-derived cardiomyocyte graft electrical activity in injured hearts

Stem cell research & therapy, 2021-01, Vol.12 (1), p.66-66, Article 66

2021

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Changes in Connexin43 Expression and Localization During Pancreatic Cancer Progression

The Journal of membrane biology, 2012-06, Vol.245 (5-6), p.255-262

2012

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Connexin43 phosphorylation: structural changes and biological effects

Specific Cx43 phosphorylation events regulate gap junction turnover in vivo

Spatio-temporal regulation of connexin43 phosphorylation and gap junction dynamics

Kinase programs spatiotemporally regulate gap junction assembly and disassembly: Effects on wound repair

Cx43 phosphorylation–mediated effects on ERK and Akt protect against ischemia reperfusion injury and alter the stability of the stress-inducible protein NDRG1

Src Regulation of Cx43 Phosphorylation and Gap Junction Turnover

Cx43 phosphorylation sites regulate pancreatic cancer metastasis

Connexin43 phosphorylation in brain, cardiac, endothelial and epithelial tissues

Connexin phosphorylation as a regulatory event linked to gap junction channel assembly

Phosphorylation of connexin 43 at MAPK, PKC or CK1 sites each distinctly alter the kinetics of epidermal wound repair

Regulation of Cx37 channel and growth-suppressive properties by phosphorylation

Key connexin 43 phosphorylation events regulate the gap junction life cycle

The lipidated connexin mimetic peptide SRPTEKT- Hdc is a potent inhibitor of Cx43 channels with specificity for the pS368 phospho-isoform

CD133 as a Biomarker for an Autoantibody-to-ImmunoPET Paradigm for the Early Detection of Small Cell Lung Cancer

Posttranslational modifications induce autoantibodies with risk prediction capability in patients with small cell lung cancer

Casein Kinase 1 Phosphomimetic Mutations Negatively Impact Connexin-43 Gap Junctions in Human Pluripotent Stem Cell-Derived Cardiomyocytes

Optical mapping of human embryonic stem cell-derived cardiomyocyte graft electrical activity in injured hearts

Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC

Trafficking and Recycling of the Connexin43 Gap Junction Protein during Mitosis

The C-terminus of connexin43 adopts different conformations in the Golgi and gap junction as detected with structure-specific antibodies

Connexin 43 Interacts with Zona Occludens-1 and -2 Proteins in a Cell Cycle Stage-specific Manner

CASK (LIN2) interacts with Cx43 in wounded skin and their coexpression affects cell migration

Spatiotemporal Proteomic Analyses during Pancreas Cancer Progression Identifies Serine/Threonine Stress Kinase 4 (STK4) as a Novel Candidate Biomarker for Early Stage Disease

Correction to: Optical mapping of human embryonic stem cell-derived cardiomyocyte graft electrical activity in injured hearts

Changes in Connexin43 Expression and Localization During Pancreatic Cancer Progression

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