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Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease

Digestive Diseases and Sciences, 2016-05, Vol.61 (5), p.1282-1293

2016

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Evolving Role for Pharmacotherapy in NAFLD/NASH

Clinical and translational science, 2021-01, Vol.14 (1), p.11-19

2021

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Interactions between Gut Microbiota, Host Genetics and Diet Modulate the Predisposition to Obesity and Metabolic Syndrome

Cell metabolism, 2015-09, Vol.22 (3), p.516-530

2015

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Fructose metabolism by the guts cuts liver fat

Journal of molecular medicine (Berlin, Germany), 2020-05, Vol.98 (5), p.733-734

2020

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Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation

Molecular cell, 2019-05, Vol.74 (4), p.844-857.e7

2019

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Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

The Journal of clinical investigation, 2017-11, Vol.127 (11), p.4059-4074

2017

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Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins

Cell metabolism, 2019-10, Vol.30 (4), p.735-753.e4

2019

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Antibiotic effects on gut microbiota and metabolism are host dependent

The Journal of clinical investigation, 2016-12, Vol.126 (12), p.4430-4443

2016

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Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function

Diabetes (New York, N.Y.), 2016-08, Vol.65 (8), p.2201-2213

2016

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Fructose Metabolism and Metabolic Dysfunction in Adolescents and Young Adults

Nutrients, 2023-07, Vol.15 (14), p.3162

2023

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Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD

Diabetes (New York, N.Y.), 2016-08, Vol.65 (8), p.2187-2200

2016

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IL‐17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice

Hepatology (Baltimore, Md.), 2014-05, Vol.59 (5), p.1830-1839

2014

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Dietary Counseling Aimed at Reducing Sugar Intake Yields the Greatest Improvement in Management of Weight and Metabolic Dysfunction in Children with Obesity

Nutrients, 2022-04, Vol.14 (7), p.1500

2022

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Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis

The Journal of clinical investigation, 2016-09, Vol.126 (9), p.3433-3446

2016

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Tissue-Specific Fructose Metabolism in Obesity and Diabetes

Current diabetes reports, 2020-10, Vol.20 (11), p.64-64, Article 64

2020

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High‐fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis

Hepatology (Baltimore, Md.), 2010-09, Vol.52 (3), p.934-944

2010

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Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens

Diabetes (New York, N.Y.), 2021-08, Vol.70 (8), p.1857-1873

2021

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Liver-specific FGFR4 knockdown in mice on an HFD increases bile acid synthesis and improves hepatic steatosis

Journal of lipid research, 2023-02, Vol.64 (2), p.100324-100324, Article 100324

2023

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Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose

PloS one, 2018-12, Vol.13 (12), p.e0208973-e0208973

2018

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Hepatic kinome atlas: An in‐depth identification of kinase pathways in liver fibrosis of humans and rodents

Hepatology (Baltimore, Md.), 2022-11, Vol.76 (5), p.1376-1388

2022

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Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance

Diabetes (New York, N.Y.), 2020-11, Vol.69 (11), p.2294-2309

2020

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Role of p110a subunit of PI3-kinase in skeletal muscle mitochondrial homeostasis and metabolism

Nature communications, 2019-07, Vol.10 (1), p.3412-14, Article 3412

2019

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Non-hematopoietic IL-4Rα expression contributes to fructose-driven obesity and metabolic sequelae

International Journal of Obesity, 2021-11, Vol.45 (11), p.2377-2387

2021

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Stratification by obesity class, rather than age, can identify a higher percent of children at risk for non‐alcoholic fatty liver disease and metabolic dysfunction

Pediatric obesity, 2022-03, Vol.17 (3), p.e12862-n/a

2022

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Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease

Evolving Role for Pharmacotherapy in NAFLD/NASH

Interactions between Gut Microbiota, Host Genetics and Diet Modulate the Predisposition to Obesity and Metabolic Syndrome

Fructose metabolism by the guts cuts liver fat

Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins

Antibiotic effects on gut microbiota and metabolism are host dependent

Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function

Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling

Fructose Metabolism and Metabolic Dysfunction in Adolescents and Young Adults

Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD

IL‐17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice

Dietary Counseling Aimed at Reducing Sugar Intake Yields the Greatest Improvement in Management of Weight and Metabolic Dysfunction in Children with Obesity

Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis

Tissue-Specific Fructose Metabolism in Obesity and Diabetes

High‐fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis

Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens

Liver-specific FGFR4 knockdown in mice on an HFD increases bile acid synthesis and improves hepatic steatosis

Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose

Hepatic kinome atlas: An in‐depth identification of kinase pathways in liver fibrosis of humans and rodents

Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance

Role of p110a subunit of PI3-kinase in skeletal muscle mitochondrial homeostasis and metabolism

Non-hematopoietic IL-4Rα expression contributes to fructose-driven obesity and metabolic sequelae

Stratification by obesity class, rather than age, can identify a higher percent of children at risk for non‐alcoholic fatty liver disease and metabolic dysfunction

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