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Tumor suppressor immune gene therapy to reverse immunotherapy resistance

Cancer gene therapy, 2022-06, Vol.29 (6), p.825-834

2022

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Analysis of Adenoviral p53 Gene Therapy Clinical Trials in Recurrent Head and Neck Squamous Cell Carcinoma

Frontiers in oncology, 2021-04, Vol.11, p.645745-645745

2021

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Biomarkers Predict p53 Gene Therapy Efficacy in Recurrent Squamous Cell Carcinoma of the Head and Neck

Clinical cancer research, 2009-12, Vol.15 (24), p.7719-7725

2009

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p53 therapy in a patient with Li-Fraumeni syndrome

Molecular cancer therapeutics, 2007-05, Vol.6 (5), p.1478-1482

2007

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The Unwritten Chapters Gene Therapy of Cancer, 2nd ed

Molecular Therapy, 2002-06, Vol.5 (6), p.664-664

Sobol, Robert E.

2002

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Reversing immune checkpoint inhibitor resistance with adenoviral IL-24 and p53 tumor suppressor immune gene therapy

Journal of clinical oncology, 2018-02, Vol.36 (5_suppl), p.64-64

2018

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Improved cancer vaccines through gene transfer

Cancer gene therapy, 2005-06, Vol.12 (6), p.515-515

2005

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Effect of adenoviral p53 (Ad-p53) tumor suppressor immune gene therapy on checkpoint inhibitor resistance and abscopal therapeutic efficacy

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.e14610-e14610

2017

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943. Prognostic Determinants Associated with Efficacy of Adenoviral p53 Gene Therapy in Patients with Recurrent Squamous Cell Carcinoma of the Head and Neck

Molecular therapy, 2006-05, Vol.13 (S1), p.S364

2006

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Use of wild-type p53 to achieve complete treatment sensitization of tumor cells expressing endogenous mutant p53

Molecular carcinogenesis, 1995-12, Vol.14 (4), p.275-285

1995

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Clinical Importance of Myeloid Antigen Expression in Adult Acute Lymphoblastic Leukemia

The New England journal of medicine, 1987-04, Vol.316 (18), p.1111-1117

1987

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Hormone-Negative, Chromogranin a-Positive Endocrine Tumors

The New England journal of medicine, 1989-02, Vol.320 (7), p.444-447

1989

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Eradication of Established Intracranial Rat Gliomas by Transforming Growth Factor β Antisense Gene Therapy

Proceedings of the National Academy of Sciences - PNAS, 1996-04, Vol.93 (7), p.2909-2914

1996

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Interleukin 2 gene therapy of colorectal carcinoma with autologous irradiated tumor cells and genetically engineered fibroblasts : A phase I study

Clinical cancer research, 1999-09, Vol.5 (9), p.2359-2365

1999

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Chronic Lymphocytic Leukemia and Other Chronic Lymphoid Proliferations : Surface Marker Phenotypes and Clinical Correlations

Journal of clinical oncology, 2008, Vol.26 (8)

2008

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Clinical Significance of the BCR-ABL Fusion Gene in Adult Acute Lymphoblastic Leukemia: A Cancer and Leukemia Group B Study (8762)

Blood, 1992-12, Vol.80 (12), p.2983-2990

1992

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Lack of radioimmunodetection and complications associated with monoclonal anticarcinoembryonic antigen antibody cross-reactivity with an antigen on circulating cells

Cancer research (Chicago, Ill.), 1984-05, Vol.44 (5), p.2213-2218

1984

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1007. Safety of Adenoviral Vectors: Results of Clinical Investigations in 445 Cancer Patients Treated with Advexin® (Adenoviral p53) Gene Therapy

Molecular therapy, 2004-05, Vol.9 (S1), p.S385-S386

2004

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Cytokine gene therapy with interleukin-2-transduced fibroblasts: effects of IL-2 dose on anti-tumor immunity

Human gene therapy, 1995-05, Vol.6 (5), p.591-601

1995

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Characteristics of CD11c+CD5+ Chronic B-Cell Leukemias and the Identification of Novel Peripheral Blood B-Cell Subsets With Chronic Lymphoid Leukemia Immunophenotypes

Blood, 1990-07, Vol.76 (1), p.123-130

1990

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Epidermal Growth Factor Receptor Expression in Human Lung Carcinomas Defined by a Monoclonal Antibody

JNCI : Journal of the National Cancer Institute, 1987-09, Vol.79 (3), p.403-407

1987

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Injection of colon carcinoma patients with autologous irradiated tumor cells and fibroblasts genetically modified to secrete interleukin-2 (IL-2): a phase I study

Human gene therapy, 1995-02, Vol.6 (2), p.195-204

1995

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Elevated serum chromogranin A concentrations in small-cell lung carcinoma

Annals of internal medicine, 1986-11, Vol.105 (5), p.698

1986

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Trisomy 13: A New Recurring Chromosome Abnormality in Acute Leukemia

Blood, 1990-10, Vol.76 (8), p.1614-1621

1990

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Tumor suppressor immune gene therapy to reverse immunotherapy resistance

Analysis of Adenoviral p53 Gene Therapy Clinical Trials in Recurrent Head and Neck Squamous Cell Carcinoma

Biomarkers Predict p53 Gene Therapy Efficacy in Recurrent Squamous Cell Carcinoma of the Head and Neck

p53 therapy in a patient with Li-Fraumeni syndrome

The Unwritten Chapters Gene Therapy of Cancer, 2nd ed

Reversing immune checkpoint inhibitor resistance with adenoviral IL-24 and p53 tumor suppressor immune gene therapy

Improved cancer vaccines through gene transfer

Effect of adenoviral p53 (Ad-p53) tumor suppressor immune gene therapy on checkpoint inhibitor resistance and abscopal therapeutic efficacy

943. Prognostic Determinants Associated with Efficacy of Adenoviral p53 Gene Therapy in Patients with Recurrent Squamous Cell Carcinoma of the Head and Neck

Use of wild-type p53 to achieve complete treatment sensitization of tumor cells expressing endogenous mutant p53

Clinical Importance of Myeloid Antigen Expression in Adult Acute Lymphoblastic Leukemia

Hormone-Negative, Chromogranin a-Positive Endocrine Tumors

Eradication of Established Intracranial Rat Gliomas by Transforming Growth Factor β Antisense Gene Therapy

A Five-Drug Remission Induction Regimen With Intensive Consolidation for Adults With Acute Lymphoblastic Leukemia: Cancer and Leukemia Group B Study 8811

Interleukin 2 gene therapy of colorectal carcinoma with autologous irradiated tumor cells and genetically engineered fibroblasts : A phase I study

Chronic Lymphocytic Leukemia and Other Chronic Lymphoid Proliferations : Surface Marker Phenotypes and Clinical Correlations

Clinical Significance of the BCR-ABL Fusion Gene in Adult Acute Lymphoblastic Leukemia: A Cancer and Leukemia Group B Study (8762)

Lack of radioimmunodetection and complications associated with monoclonal anticarcinoembryonic antigen antibody cross-reactivity with an antigen on circulating cells

1007. Safety of Adenoviral Vectors: Results of Clinical Investigations in 445 Cancer Patients Treated with Advexin® (Adenoviral p53) Gene Therapy

Cytokine gene therapy with interleukin-2-transduced fibroblasts: effects of IL-2 dose on anti-tumor immunity

Characteristics of CD11c+CD5+ Chronic B-Cell Leukemias and the Identification of Novel Peripheral Blood B-Cell Subsets With Chronic Lymphoid Leukemia Immunophenotypes

Epidermal Growth Factor Receptor Expression in Human Lung Carcinomas Defined by a Monoclonal Antibody

Injection of colon carcinoma patients with autologous irradiated tumor cells and fibroblasts genetically modified to secrete interleukin-2 (IL-2): a phase I study

Elevated serum chromogranin A concentrations in small-cell lung carcinoma

Trisomy 13: A New Recurring Chromosome Abnormality in Acute Leukemia

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