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NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice

The Journal of immunology (1950), 2012-08, Vol.189 (4), p.2006-2016

2012

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Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice

Nature communications, 2021-05, Vol.12 (1), p.2574-2574, Article 2574

2021

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AT1A Angiotensin Receptors in the Renal Proximal Tubule Regulate Blood Pressure

Cell metabolism, 2011-04, Vol.13 (4), p.469-475

2011

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Species-specific NLRP3 regulation and its role in CNS autoinflammatory diseases

Cell reports (Cambridge), 2024-03, Vol.43 (3), p.113852-113852, Article 113852

2024

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Human ACE2 expression, a major tropism determinant for SARS-CoV-2, is regulated by upstream and intragenic elements

PLoS pathogens, 2023-02, Vol.19 (2), p.e1011168-e1011168

2023

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Beyond detoxification: Pleiotropic functions of multiple glutathione S-transferase isoforms protect mice against a toxic electrophile

PloS one, 2019-11, Vol.14 (11), p.e0225449

2019

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An NLRP3 Mutation Causes Arthropathy and Osteoporosis in Humanized Mice

Cell reports (Cambridge), 2016-12, Vol.17 (11), p.3077-3088

2016

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Xenobiotic Metabolism in Mice Lacking the UDP-Glucuronosyltransferase 2 Family

Drug metabolism and disposition, 2015-12, Vol.43 (12), p.1838-1846

2015

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Deficits in sensorimotor gating and tests of social behavior in a genetic model of reduced NMDA receptor function

Behavioural brain research, 2004-08, Vol.153 (2), p.507-519

2004

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Mice lacking three Loci encoding 14 glutathione transferase genes: a novel tool for assigning function to the GSTP, GSTM, and GSTT families

Drug metabolism and disposition, 2014-06, Vol.42 (6), p.1074

2014

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Arsenic Metabolism in Mice Carrying a BORCS7/AS3MT Locus Humanized by Syntenic Replacement

Environmental health perspectives, 2020-08, Vol.128 (8), p.87003

2020

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Allergic inflammation induces a persistent mechanistic switch in thromboxane-mediated airway constriction in the mouse

American journal of physiology. Lung cellular and molecular physiology, 2012-01, Vol.302 (1), p.L140-L151

2012

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Target Cell Activation of a Structurally Novel NOD-Like Receptor Pyrin Domain-Containing Protein 3 Inhibitor NT-0796 Enhances Potency

The Journal of pharmacology and experimental therapeutics, 2024-03, Vol.388 (3), p.798

2024

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Elarekibep (PRS-060/AZD1402), a new class of inhaled Anticalin medicine targeting IL-4Ra for type 2 endotype asthma

Journal of allergy and clinical immunology, 2023-04, Vol.151 (4), p.966-975

2023

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Oxysterols Modify NLRP2 in Epithelial Cells, Identifying a Mediator of Ozone-induced Inflammation

American journal of respiratory cell and molecular biology, 2021-11, Vol.65 (5), p.500-512

2021

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Determination of the Contribution of Cysteinyl Leukotrienes and Leukotriene B4 in Acute Inflammatory Responses Using 5-Lipoxygenase- and Leukotriene A4 Hydrolase-Deficient Mice

The Journal of immunology (1950), 1999-12, Vol.163 (12), p.6810-6819

1999

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An Animal Model for Cystic Fibrosis Made by Gene Targeting

Science (American Association for the Advancement of Science), 1992-08, Vol.257 (5073), p.1083-1088

1992

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A Mutation in the Borcs7 Subunit of the Lysosome Regulatory BORC Complex Results in Motor Deficits and Dystrophic Axonopathy in Mice

Cell reports (Cambridge), 2018-07, Vol.24 (5), p.1254-1265

2018

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RabGEF1 is a negative regulator of mast cell activation and skin inflammation

Nature immunology, 2004-08, Vol.5 (8), p.844-852

2004

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Thromboxane Receptors in Smooth Muscle Promote Hypertension, Vascular Remodeling, and Sudden Death

Hypertension (Dallas, Tex. 1979), 2013-01, Vol.61 (1), p.166-173

2013

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The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth

Nature (London), 1997-11, Vol.390 (6655), p.78-81

1997

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BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a brca1 transgene

Oncogene, 1999-12, Vol.18 (55), p.7900-7907

1999

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Expression and function of NPSR1/GPRA in the lung before and after induction of asthma-like disease

American journal of physiology. Lung cellular and molecular physiology, 2006-11, Vol.291 (5), p.L1005-L1017

2006

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Alterations in regional brain metabolism in genetic and pharmacological models of reduced NMDA receptor function

Brain research, 2002-10, Vol.951 (2), p.166-176

2002

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Altered Inflammatory Responses in Leukotriene-Deficient Mice

Proceedings of the National Academy of Sciences - PNAS, 1994-12, Vol.91 (26), p.12852-12856

1994

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NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice

Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice

AT1A Angiotensin Receptors in the Renal Proximal Tubule Regulate Blood Pressure

Species-specific NLRP3 regulation and its role in CNS autoinflammatory diseases

Human ACE2 expression, a major tropism determinant for SARS-CoV-2, is regulated by upstream and intragenic elements

Beyond detoxification: Pleiotropic functions of multiple glutathione S-transferase isoforms protect mice against a toxic electrophile

An NLRP3 Mutation Causes Arthropathy and Osteoporosis in Humanized Mice

Xenobiotic Metabolism in Mice Lacking the UDP-Glucuronosyltransferase 2 Family

Deficits in sensorimotor gating and tests of social behavior in a genetic model of reduced NMDA receptor function

Mice lacking three Loci encoding 14 glutathione transferase genes: a novel tool for assigning function to the GSTP, GSTM, and GSTT families

Arsenic Metabolism in Mice Carrying a BORCS7/AS3MT Locus Humanized by Syntenic Replacement

Allergic inflammation induces a persistent mechanistic switch in thromboxane-mediated airway constriction in the mouse

Target Cell Activation of a Structurally Novel NOD-Like Receptor Pyrin Domain-Containing Protein 3 Inhibitor NT-0796 Enhances Potency

Elarekibep (PRS-060/AZD1402), a new class of inhaled Anticalin medicine targeting IL-4Ra for type 2 endotype asthma

Oxysterols Modify NLRP2 in Epithelial Cells, Identifying a Mediator of Ozone-induced Inflammation

Determination of the Contribution of Cysteinyl Leukotrienes and Leukotriene B4 in Acute Inflammatory Responses Using 5-Lipoxygenase- and Leukotriene A4 Hydrolase-Deficient Mice

An Animal Model for Cystic Fibrosis Made by Gene Targeting

A Mutation in the Borcs7 Subunit of the Lysosome Regulatory BORC Complex Results in Motor Deficits and Dystrophic Axonopathy in Mice

RabGEF1 is a negative regulator of mast cell activation and skin inflammation

Thromboxane Receptors in Smooth Muscle Promote Hypertension, Vascular Remodeling, and Sudden Death

The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth

BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a brca1 transgene

Expression and function of NPSR1/GPRA in the lung before and after induction of asthma-like disease

Alterations in regional brain metabolism in genetic and pharmacological models of reduced NMDA receptor function

Altered Inflammatory Responses in Leukotriene-Deficient Mice

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