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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Nature (London), 1995-07, Vol.376 (6535), p.37-43

1995

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Gene Knockout or Pharmacological Inhibition of Poly(ADP-Ribose) Polymerase-1 Prevents Lung Inflammation in a Murine Model of Asthma

American journal of respiratory cell and molecular biology, 2003-03, Vol.28 (3), p.322-329

2003

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Transcriptional Repression by Binding of Poly(ADP-ribose) Polymerase to Promoter Sequences

The Journal of biological chemistry, 2002-01, Vol.277 (1), p.665-670

2002

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Polyubiquitylation of PARP-1 through ubiquitin K48 is modulated by activated DNA, NAD+, and dipeptides

Journal of cellular biochemistry, 2008-05, Vol.104 (1), p.318-328

2008

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Apoptotic DNA Fragmentation May Be a Cooperative Activity between Caspase-activated Deoxyribonuclease and the Poly(ADP-ribose) Polymerase-regulated DNAS1L3, an Endoplasmic Reticulum-localized Endonuclease That Translocates to the Nucleus during Apoptosis

The Journal of biological chemistry, 2013-02, Vol.288 (5), p.3460-3468

2013

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A novel in vivo post‐translational modification of p53 by PARP‐1 in MPTP‐induced parkinsonism

Journal of neurochemistry, 2002-10, Vol.83 (1), p.186-192

2002

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The E7 protein of human papillomavirus type 16 sensitizes primary human keratinocytes to apoptosis

Oncogene, 1998-09, Vol.17 (10), p.1207-1214

1998

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Phosphorylation of p50 NF-κB at a Single Serine Residue by DNA-dependent Protein Kinase Is Critical for VCAM-1 Expression upon TNF Treatment

The Journal of biological chemistry, 2010-12, Vol.285 (52), p.41152-41160

2010

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Regulation of α-Synuclein Expression by Poly (ADP Ribose) Polymerase-1 (PARP-1) Binding to the NACP-Rep1 Polymorphic Site Upstream of the SNCA Gene

American journal of human genetics, 2005-03, Vol.76 (3), p.478-492

2005

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Regulation of the Expression or Recruitment of Components of the DNA Synthesome by Poly(ADP-Ribose) Polymerase

Biochemistry (Easton), 1998-06, Vol.37 (26), p.9363-9370

1998

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Poly(ADP-Ribose) Polymerase Activation Mediates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-Induced Parkinsonism

Proceedings of the National Academy of Sciences - PNAS, 1999-05, Vol.96 (10), p.5774-5779

1999

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Sphingosine 1-Phosphate Inhibits Activation of Caspases that Cleave Poly(ADP-ribose) Polymerase and Lamins during Fas- and Ceramide-mediated Apoptosis in Jurkat T Lymphocytes

The Journal of biological chemistry, 1998-01, Vol.273 (5), p.2910-2916

1998

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Transient Poly(ADP-ribosyl)ation of Nuclear Proteins and Role of Poly(ADP-ribose) Polymerase in the Early Stages of Apoptosis

The Journal of biological chemistry, 1998-05, Vol.273 (22), p.13703-13712

1998

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Phenoxodiol inhibits growth of metastatic prostate cancer cells

The Prostate, 2010-08, Vol.70 (11), p.1211-1221

2010

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Prolonged poly(ADP-ribose) polymerase-1 activity regulates JP-8-induced sustained cytokine expression in alveolar macrophages

Free radical biology & medicine, 2007-05, Vol.42 (9), p.1430-1440

2007

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Induction of apoptosis in proliferating human endothelial cells by the tumor-specific antiangiogenesis agent combretastatin A-4

Cancer research (Chicago, Ill.), 1998-10, Vol.58 (20), p.4510-4514

1998

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PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phase

Oncogene, 2003-11, Vol.22 (52), p.8460-8471

2003

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Misregulation of Gene Expression in Primary Fibroblasts Lacking Poly(ADP-Ribose) Polymerase

Proceedings of the National Academy of Sciences - PNAS, 2000-10, Vol.97 (21), p.11274-11279

2000

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Protection by antioxidants against toxicity and apoptosis induced by the sulphur mustard analog 2‐chloroethylethyl sulphide (CEES) in Jurkat T cells and normal human lymphocytes

British journal of pharmacology, 2004-03, Vol.141 (5), p.795-802

2004

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A Role of the Ca2+/Mg2+-dependent Endonuclease in Apoptosis and Its Inhibition by Poly(ADP-ribose) Polymerase

The Journal of biological chemistry, 2000-07, Vol.275 (28), p.21302-21308

2000

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Poly(ADP-ribosyl)ation of p53 during apoptosis in human osteosarcoma cells

Cancer research (Chicago, Ill.), 1999-05, Vol.59 (9), p.2190-2194

1999

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Roles of DNA Fragmentation Factor and Poly(ADP-ribose) Polymerase in an Amplification Phase of Tumor Necrosis Factor-induced Apoptosis

The Journal of biological chemistry, 2001-10, Vol.276 (41), p.38185-38192

2001

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Chromosomal Aberrations in PARP-/- Mice: Genome Stabilization in Immortalized Cells by Reintroduction of Poly(ADP-Ribose) Polymerase cDNA

Proceedings of the National Academy of Sciences - PNAS, 1999-11, Vol.96 (23), p.13191-13196

1999

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Regulation of DNAS1L3 endonuclease activity by poly(ADP-ribosyl)ation during etoposide-induced apoptosis. Role of poly(ADP-ribose) polymerase-1 cleavage in endonuclease activation

The Journal of biological chemistry, 2002-01, Vol.277 (1), p.372-378

2002

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Involvement of PARP and poly(ADP-ribosyl)ation in the early stages of apoptosis and DNA replication

Molecular and cellular biochemistry, 1999-03, Vol.193 (1-2), p.137-148

1999

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Gene Knockout or Pharmacological Inhibition of Poly(ADP-Ribose) Polymerase-1 Prevents Lung Inflammation in a Murine Model of Asthma

Transcriptional Repression by Binding of Poly(ADP-ribose) Polymerase to Promoter Sequences

Polyubiquitylation of PARP-1 through ubiquitin K48 is modulated by activated DNA, NAD+, and dipeptides

Apoptotic DNA Fragmentation May Be a Cooperative Activity between Caspase-activated Deoxyribonuclease and the Poly(ADP-ribose) Polymerase-regulated DNAS1L3, an Endoplasmic Reticulum-localized Endonuclease That Translocates to the Nucleus during Apoptosis

A novel in vivo post‐translational modification of p53 by PARP‐1 in MPTP‐induced parkinsonism

The E7 protein of human papillomavirus type 16 sensitizes primary human keratinocytes to apoptosis

Phosphorylation of p50 NF-κB at a Single Serine Residue by DNA-dependent Protein Kinase Is Critical for VCAM-1 Expression upon TNF Treatment

Regulation of α-Synuclein Expression by Poly (ADP Ribose) Polymerase-1 (PARP-1) Binding to the NACP-Rep1 Polymorphic Site Upstream of the SNCA Gene

Regulation of the Expression or Recruitment of Components of the DNA Synthesome by Poly(ADP-Ribose) Polymerase

Poly(ADP-Ribose) Polymerase Activation Mediates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-Induced Parkinsonism

Sphingosine 1-Phosphate Inhibits Activation of Caspases that Cleave Poly(ADP-ribose) Polymerase and Lamins during Fas- and Ceramide-mediated Apoptosis in Jurkat T Lymphocytes

Transient Poly(ADP-ribosyl)ation of Nuclear Proteins and Role of Poly(ADP-ribose) Polymerase in the Early Stages of Apoptosis

Phenoxodiol inhibits growth of metastatic prostate cancer cells

Prolonged poly(ADP-ribose) polymerase-1 activity regulates JP-8-induced sustained cytokine expression in alveolar macrophages

Induction of apoptosis in proliferating human endothelial cells by the tumor-specific antiangiogenesis agent combretastatin A-4

PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phase

Misregulation of Gene Expression in Primary Fibroblasts Lacking Poly(ADP-Ribose) Polymerase

Protection by antioxidants against toxicity and apoptosis induced by the sulphur mustard analog 2‐chloroethylethyl sulphide (CEES) in Jurkat T cells and normal human lymphocytes

A Role of the Ca2+/Mg2+-dependent Endonuclease in Apoptosis and Its Inhibition by Poly(ADP-ribose) Polymerase

Poly(ADP-ribosyl)ation of p53 during apoptosis in human osteosarcoma cells

Roles of DNA Fragmentation Factor and Poly(ADP-ribose) Polymerase in an Amplification Phase of Tumor Necrosis Factor-induced Apoptosis

Chromosomal Aberrations in PARP-/- Mice: Genome Stabilization in Immortalized Cells by Reintroduction of Poly(ADP-Ribose) Polymerase cDNA

Regulation of DNAS1L3 endonuclease activity by poly(ADP-ribosyl)ation during etoposide-induced apoptosis. Role of poly(ADP-ribose) polymerase-1 cleavage in endonuclease activation

Involvement of PARP and poly(ADP-ribosyl)ation in the early stages of apoptosis and DNA replication

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