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Heterogeneous Blood-Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer

Clinical cancer research, 2010-12, Vol.16 (23), p.5664-5678

2010

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Lapatinib Distribution in HER2 Overexpressing Experimental Brain Metastases of Breast Cancer

Pharmaceutical research, 2012-03, Vol.29 (3), p.770-781

2012

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Brain penetrating peptides and peptide–drug conjugates to overcome the blood–brain barrier and target CNS diseases

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 2021-07, Vol.13 (4), p.e1695-n/a

2021

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Chemotherapy Delivery Issues in Central Nervous System Malignancy: A Reality Check

Journal of clinical oncology, 2007-06, Vol.25 (16), p.2295-2305

2007

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Brain uptake of nonsteroidal anti-inflammatory drugs : Ibuprofen, flurbiprofen, and indomethacin

Pharmaceutical research, 2006-05, Vol.23 (5), p.873-881

2006

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Transport of Glutamate and Other Amino Acids at the Blood-Brain Barrier

The Journal of nutrition, 2000-04, Vol.130 (4), p.1016S-1022S

Smith, Quentin R.

2000

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Vorinostat Inhibits Brain Metastatic Colonization in a Model of Triple-Negative Breast Cancer and Induces DNA Double-Strand Breaks

Clinical cancer research, 2009-10, Vol.15 (19), p.6148-6157

2009

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Brain metastases as preventive and therapeutic targets

Nature reviews. Cancer, 2011-05, Vol.11 (5), p.352

2011

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A balanced view of choroid plexus structure and function: Focus on adult humans

Experimental neurology, 2015-05, Vol.267, p.78-86

2015

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Studies of imipramine binding to human serum albumin by high-performance affinity chromatography

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009-04, Vol.877 (11), p.1149-1154

2009

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Role of site-specific binding to plasma albumin in drug availability to brain

The Journal of pharmacology and experimental therapeutics, 2006-05, Vol.317 (2), p.667

2006

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Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study

Neuro-oncology (Charlottesville, Va.), 2015-02, Vol.17 (2), p.289-295

2015

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Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer

Pharmaceutical research, 2016-12, Vol.33 (12), p.2904-2919

2016

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Uptake of ANG1005, A Novel Paclitaxel Derivative, Through the Blood-Brain Barrier into Brain and Experimental Brain Metastases of Breast Cancer

Pharmaceutical research, 2009-11, Vol.26 (11), p.2486-2494

2009

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Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis

Clinical cancer research, 2021-08, Vol.27 (15), p.4422-4434

2021

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Characterization of the blood–brain barrier choline transporter using the in situ rat brain perfusion technique

Journal of neurochemistry, 2001-02, Vol.76 (4), p.1032-1041

2001

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Paclitaxel-hyaluronic nanoconjugates prolong overall survival in a preclinical brain metastases of breast cancer model

Molecular cancer therapeutics, 2013-11, Vol.12 (11), p.2389-2399

2013

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Liquid chromatography–tandem mass spectrometry for the determination of methylprednisolone in rat plasma and liver after intravenous administration of its liver-targeted dextran prodrug

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009-04, Vol.877 (10), p.927-932

2009

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Kinetic studies of drug–protein interactions by using peak profiling and high-performance affinity chromatography: Examination of multi-site interactions of drugs with human serum albumin columns

Journal of Chromatography A, 2011-04, Vol.1218 (15), p.2065-2071

2011

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CNS Anticancer Drug Discovery and Development Conference White Paper

Neuro-oncology, 2015-11, Vol.17 Suppl 6 (suppl 6), p.vi1-vi26

2015

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A review of blood-brain barrier transport techniques

Methods in molecular medicine, 2003, Vol.89, p.193

Smith, Quentin R

2003

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Regiospecific and conformationally restrained analogs of melphalan and dl-2-NAM-7 and their affinities for the large neutral amino acid transporter (system LAT1) of the blood–brain barrier

Bioorganic & medicinal chemistry letters, 2010-06, Vol.20 (12), p.3688-3691

2010

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Increased expression of the MGMT repair protein mediated by cysteine prodrugs and chemopreventative natural products in human lymphocytes and tumor cell lines

Carcinogenesis (New York), 2007-02, Vol.28 (2), p.378-389

2007

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Brain Uptake, Pharmacokinetics, and Tissue Distribution in the Rat of Neurotoxic N-Butylbenzenesulfonamide

Toxicological sciences, 2007-06, Vol.97 (2), p.253-264

2007

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Fatty acid uptake and incorporation in brain: studies with the perfusion model

Journal of molecular neuroscience, 2001-04, Vol.16 (2-3), p.167-172

2001

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Heterogeneous Blood-Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer

Lapatinib Distribution in HER2 Overexpressing Experimental Brain Metastases of Breast Cancer

Brain penetrating peptides and peptide–drug conjugates to overcome the blood–brain barrier and target CNS diseases

Chemotherapy Delivery Issues in Central Nervous System Malignancy: A Reality Check

Brain uptake of nonsteroidal anti-inflammatory drugs : Ibuprofen, flurbiprofen, and indomethacin

Transport of Glutamate and Other Amino Acids at the Blood-Brain Barrier

Vorinostat Inhibits Brain Metastatic Colonization in a Model of Triple-Negative Breast Cancer and Induces DNA Double-Strand Breaks

Brain metastases as preventive and therapeutic targets

A balanced view of choroid plexus structure and function: Focus on adult humans

Studies of imipramine binding to human serum albumin by high-performance affinity chromatography

Role of site-specific binding to plasma albumin in drug availability to brain

Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study

Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer

Uptake of ANG1005, A Novel Paclitaxel Derivative, Through the Blood-Brain Barrier into Brain and Experimental Brain Metastases of Breast Cancer

Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis

Characterization of the blood–brain barrier choline transporter using the in situ rat brain perfusion technique

Paclitaxel-hyaluronic nanoconjugates prolong overall survival in a preclinical brain metastases of breast cancer model

Liquid chromatography–tandem mass spectrometry for the determination of methylprednisolone in rat plasma and liver after intravenous administration of its liver-targeted dextran prodrug

Kinetic studies of drug–protein interactions by using peak profiling and high-performance affinity chromatography: Examination of multi-site interactions of drugs with human serum albumin columns

CNS Anticancer Drug Discovery and Development Conference White Paper

A review of blood-brain barrier transport techniques

Regiospecific and conformationally restrained analogs of melphalan and dl-2-NAM-7 and their affinities for the large neutral amino acid transporter (system LAT1) of the blood–brain barrier

Increased expression of the MGMT repair protein mediated by cysteine prodrugs and chemopreventative natural products in human lymphocytes and tumor cell lines

Brain Uptake, Pharmacokinetics, and Tissue Distribution in the Rat of Neurotoxic N-Butylbenzenesulfonamide

Fatty acid uptake and incorporation in brain: studies with the perfusion model

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