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Characterization of LY3023414, a Novel PI3K/mTOR Dual Inhibitor Eliciting Transient Target Modulation to Impede Tumor Growth

Molecular cancer therapeutics, 2016-10, Vol.15 (10), p.2344-2356

2016

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Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications

The Journal of biological chemistry, 2013-02, Vol.288 (5), p.3500-3511

2013

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Tasisulam sodium, an antitumor agent that inhibits mitotic progression and induces vascular normalization

Molecular cancer therapeutics, 2011-11, Vol.10 (11), p.2168-2178

2011

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Insulin-like growth factor II receptor as a multifunctional binding protein

Nature (London), 1987-09, Vol.329 (6137), p.301-307

1987

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Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, in Human Cancer Cells

The Journal of biological chemistry, 2013-02, Vol.288 (5), p.3500-3511

2013

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4-Substituted d-Glutamic Acid Analogues: The First Potent Inhibitors of Glutamate Racemase (MurI) Enzyme with Antibacterial Activity

Journal of medicinal chemistry, 2002-09, Vol.45 (20), p.4559-4570

2002

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Cloning, expression, purification, and characterization of the human Class Ia phosphoinositide 3-kinase isoforms

Protein expression and purification, 2004-06, Vol.35 (2), p.218-224

2004

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Synthesis of fluorescent derivatives of wortmannin and demethoxyviridin as probes for phosphatidylinositol 3-kinase

Bioorganic & medicinal chemistry letters, 2006-05, Vol.16 (9), p.2518-2521

2006

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Demonstrating the intrinsic ion channel activity of virally encoded proteins

FEBS Letters, 2003-09, Vol.552 (1), p.61-67

2003

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Efficacy of LY2784544, a Small Molecule Inhibitor Selective for Mutant JAK2 Kinase, In JAK2 V617F-Induced Hematologic Malignancy Models

Blood, 2010-11, Vol.116 (21), p.4087-4087

2010

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Immobilized iminodiacetic acid metal peptide complexes. Identification of chelating peptide purification handles for recombinant proteins

Inorganic chemistry, 1987-06, Vol.26 (12), p.1965-1969

1987

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Rates of hip and knee joint replacement amongst different ethnic groups in England: An analysis of National Joint Registry data

Osteoarthritis and cartilage, 2017-04, Vol.25 (4), p.448-454

2017

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Recombinant Human Insulin-Like Growth Factor II Expressed in Escherichia coli

Bio/technology (New York, N.Y. 1983), 1987-10, Vol.5 (10), p.1047-1051

1987

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Functional design of heme proteins: reaction with linear liqands

Journal of the American Chemical Society, 1980-08, Vol.102 (17), p.5666-5670

1980

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Factors modifying protective effect of anti-CD18 antibodies on myocardial reperfusion injury in dogs

American journal of physiology. Heart and circulatory physiology, 1996-01, Vol.270 (1), p.H53-H64

1996

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Engineering Metal Binding Sites into Recombinant Proteins for Facile Purification

Annals of the New York Academy of Sciences, 1991-12, Vol.646 (1), p.315-321

SMITH, MICHELE C.

1991

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Interactions of the receptor for insulin-like growth factor II with mannose-6-phosphate and antibodies to the mannose-6-phosphate receptor

Biochemical and biophysical research communications, 1987-12, Vol.149 (2), p.600-606

1987

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Measurement of insulin-like growth factor-II in physiological fluids and tissues. II. Extraction quantification in rat tissues

Endocrinology (Philadelphia), 1991-02, Vol.128 (2), p.815-822

1991

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Cationic liposome-mediated uptake of human immunodeficiency virus type 1 Tat protein into cells

Journal of virological methods, 1997-06, Vol.66 (1), p.149-157

1997

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[29] Purification and kinetic characterization of human cytomegalovirus assemblin

Methods in Enzymology, 1994, Vol.244, p.412-423

1994

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Detection of specific human immunodeficiency virus type 1 Tat-TAR complexes in the presence of mild denaturing conditions

Journal of virological methods, 1997-06, Vol.66 (1), p.91-101

1997

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Kinetically inert Co(III) linkage through an engineered metal binding site: Specific orientation of recombinant human papillomavirus type 16 E7 protein on a solid support

Methods (San Diego, Calif.), 1992, Vol.4 (1), p.73-78

1992

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Effects of second-codon mutations on expression of the insulin-like growth factor-II-encoding gene in Escherichia coli

Gene, 1991-02, Vol.98 (2), p.217-223

1991

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Catalytic hydrogenolysis of poly-iodinated recombinant human insulin-like growth factor II (IGF-II): A potentially useful method for the tritiation of IGF-II

Analytical biochemistry, 1991-11, Vol.198 (2), p.379-384

1991

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COMPARATIVE CHEMISTRY OF HEMEPROTEINS AND THE HEME OCTAPEPTIDE

SMITH, MICHELE C

1980

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Characterization of LY3023414, a Novel PI3K/mTOR Dual Inhibitor Eliciting Transient Target Modulation to Impede Tumor Growth

Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications

Tasisulam sodium, an antitumor agent that inhibits mitotic progression and induces vascular normalization

Insulin-like growth factor II receptor as a multifunctional binding protein

Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, in Human Cancer Cells

4-Substituted d-Glutamic Acid Analogues: The First Potent Inhibitors of Glutamate Racemase (MurI) Enzyme with Antibacterial Activity

Cloning, expression, purification, and characterization of the human Class Ia phosphoinositide 3-kinase isoforms

Synthesis of fluorescent derivatives of wortmannin and demethoxyviridin as probes for phosphatidylinositol 3-kinase

Demonstrating the intrinsic ion channel activity of virally encoded proteins

Efficacy of LY2784544, a Small Molecule Inhibitor Selective for Mutant JAK2 Kinase, In JAK2 V617F-Induced Hematologic Malignancy Models

Immobilized iminodiacetic acid metal peptide complexes. Identification of chelating peptide purification handles for recombinant proteins

Rates of hip and knee joint replacement amongst different ethnic groups in England: An analysis of National Joint Registry data

Recombinant Human Insulin-Like Growth Factor II Expressed in Escherichia coli

Functional design of heme proteins: reaction with linear liqands

Factors modifying protective effect of anti-CD18 antibodies on myocardial reperfusion injury in dogs

Engineering Metal Binding Sites into Recombinant Proteins for Facile Purification

Interactions of the receptor for insulin-like growth factor II with mannose-6-phosphate and antibodies to the mannose-6-phosphate receptor

Measurement of insulin-like growth factor-II in physiological fluids and tissues. II. Extraction quantification in rat tissues

Cationic liposome-mediated uptake of human immunodeficiency virus type 1 Tat protein into cells

[29] Purification and kinetic characterization of human cytomegalovirus assemblin

Detection of specific human immunodeficiency virus type 1 Tat-TAR complexes in the presence of mild denaturing conditions

Kinetically inert Co(III) linkage through an engineered metal binding site: Specific orientation of recombinant human papillomavirus type 16 E7 protein on a solid support

Effects of second-codon mutations on expression of the insulin-like growth factor-II-encoding gene in Escherichia coli

Catalytic hydrogenolysis of poly-iodinated recombinant human insulin-like growth factor II (IGF-II): A potentially useful method for the tritiation of IGF-II

COMPARATIVE CHEMISTRY OF HEMEPROTEINS AND THE HEME OCTAPEPTIDE

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