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(R)-(-)-Ketamine: The Promise of a Novel Treatment for Psychiatric and Neurological Disorders

International journal of molecular sciences, 2024-06, Vol.25 (12), p.6804

2024

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Understanding and treating moyamoya disease in children

Neurosurgical focus, 2009-04, Vol.26 (4), p.E4-E4

Smith, Jodi L

2009

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Yield of Skeletal Surveys in Children ≤18 Months of Age Presenting with Isolated Skull Fractures

The Journal of pediatrics, 2013, Vol.162 (1), p.86-89

2013

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KRM–II–81 suppresses epileptifom activity across the neural network of cortical tissue from a patient with pharmacoresistant epilepsy

Heliyon, 2024-01, Vol.10 (1), p.e23752-e23752, Article e23752

2024

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Is there a biochemical basis for purinergic P2X3 and P2X4 receptor antagonists to be considered as anti-seizure medications?

Biochemical pharmacology, 2024-04, Vol.222, p.116046-116046, Article 116046

2024

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GABAkines – Advances in the discovery, development, and commercialization of positive allosteric modulators of GABAA receptors

Pharmacology & therapeutics (Oxford), 2022-06, Vol.234, p.108035-108035, Article 108035

2022

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Clinical investigations of compounds targeting metabotropic glutamate receptors

Pharmacology, biochemistry and behavior, 2022-09, Vol.219, p.173446-173446, Article 173446

2022

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Aberrant Neuronal Avalanches in Cortical Tissue Removed From Juvenile Epilepsy Patients

Journal of clinical neurophysiology, 2010-12, Vol.27 (6), p.380-386

2010

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Targeted Blockade of TARP-γ8-Associated AMPA Receptors: Anticonvulsant Activity with the Selective Antagonist LY3130481 (CERC-611)

CNS & neurological disorders drug targets, 2017-12, Vol.16 (10), p.1099

2017

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In vitro pharmacological and rat pharmacokinetic characterization of LY3020371, a potent and selective mGlu 2/3 receptor antagonist

Neuropharmacology, 2017-03, Vol.115, p.100-114

2017

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Where do we go next in antidepressant drug discovery? A new generation of antidepressants: a pivotal role of AMPA receptor potentiation and mGlu2/3 receptor antagonism

Expert opinion on drug discovery, 2022-10, Vol.17 (10), p.1131-1146

2022

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Mechanistic and therapeutic relationships of traumatic brain injury and γ-amino-butyric acid (GABA)

Pharmacology & therapeutics (Oxford), 2024-04, Vol.256, p.108609-108609, Article 108609

2024

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Can GABAkines quiet the noise? The GABA A receptor neurobiology and pharmacology of tinnitus

Biochemical pharmacology, 2022-07, Vol.201, p.115067

2022

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Can GABAkines quiet the noise? The GABAA receptor neurobiology and pharmacology of tinnitus

Biochemical pharmacology, 2022-07, Vol.201, p.115067-115067, Article 115067

2022

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Clinical pharmacological innovation in the treatment of depression

Expert review of clinical pharmacology, 2023-04, Vol.16 (4), p.349-362

2023

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The Positive Allosteric Modulator of α 2/3-Containing GABA A Receptors, KRM-II-81, Is Active in Pharmaco-Resistant Models of Epilepsy and Reduces Hyperexcitability after Traumatic Brain Injury

The Journal of pharmacology and experimental therapeutics, 2020-01, Vol.372 (1), p.83

2020

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Rapid tolerance to behavioral effects of ethanol in rats: Prevention by R-(−)-ketamine

Pharmacology, biochemistry and behavior, 2021-04, Vol.203, p.173152, Article 173152

2021

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N-Substituted-3-alkoxy-derivatives of dextromethorphan are functional NMDA receptor antagonists in vivo: Evidence from an NMDA-induced seizure model in rats

Pharmacology, biochemistry and behavior, 2021-04, Vol.203, p.173154-173154, Article 173154

2021

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AMPA receptors play an important role in the biological consequences of spinal cord injury: Implications for AMPA receptor modulators for therapeutic benefit

Biochemical pharmacology, 2024-05, p.116302-116302, Article 116302

2024

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A Maximum Entropy Model Applied to Spatial and Temporal Correlations from Cortical Networks In Vitro

The Journal of neuroscience, 2008-01, Vol.28 (2), p.505-518

2008

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Structural Analogs of the GABAkine KRM-II-81 Are Orally Bioavailable Anticonvulsants without Sedation

The Journal of pharmacology and experimental therapeutics, 2023-04, Vol.385 (1), p.50

2023

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Long-term outcome in children with moyamoya syndrome after cranial revascularization by pial synangiosis

Journal of neurosurgery, 2004-02, Vol.100 (2 Suppl Pediatrics), p.142

2004

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Pineal gland hypermetabolic involvement without central nervous system symptoms in a pediatric patient with primary nodular sclerosis subtype classical Hodgkin Lymphoma

Pediatric hematology and oncology, 2022-02, Vol.39 (1), p.62-67

2022

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Reduction in Overt and Silent Stroke Recurrence Rate Following Cerebral Revascularization Surgery in Children with Sickle Cell Disease and Severe Cerebral Vasculopathy

Pediatric blood & cancer, 2016-08, Vol.63 (8), p.1431-1437

2016

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The value of human epileptic tissue in the characterization and development of novel antiepileptic drugs: The example of CERC-611 and KRM-II-81

Brain research, 2019-11, Vol.1722, p.146356-146356, Article 146356

2019

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(R)-(-)-Ketamine: The Promise of a Novel Treatment for Psychiatric and Neurological Disorders

Understanding and treating moyamoya disease in children

Yield of Skeletal Surveys in Children ≤18 Months of Age Presenting with Isolated Skull Fractures

KRM–II–81 suppresses epileptifom activity across the neural network of cortical tissue from a patient with pharmacoresistant epilepsy

Is there a biochemical basis for purinergic P2X3 and P2X4 receptor antagonists to be considered as anti-seizure medications?

GABAkines – Advances in the discovery, development, and commercialization of positive allosteric modulators of GABAA receptors

Clinical investigations of compounds targeting metabotropic glutamate receptors

Aberrant Neuronal Avalanches in Cortical Tissue Removed From Juvenile Epilepsy Patients

Targeted Blockade of TARP-γ8-Associated AMPA Receptors: Anticonvulsant Activity with the Selective Antagonist LY3130481 (CERC-611)

In vitro pharmacological and rat pharmacokinetic characterization of LY3020371, a potent and selective mGlu 2/3 receptor antagonist

Where do we go next in antidepressant drug discovery? A new generation of antidepressants: a pivotal role of AMPA receptor potentiation and mGlu2/3 receptor antagonism

Mechanistic and therapeutic relationships of traumatic brain injury and γ-amino-butyric acid (GABA)

Can GABAkines quiet the noise? The GABA A receptor neurobiology and pharmacology of tinnitus

Can GABAkines quiet the noise? The GABAA receptor neurobiology and pharmacology of tinnitus

Clinical pharmacological innovation in the treatment of depression

The Positive Allosteric Modulator of α 2/3-Containing GABA A Receptors, KRM-II-81, Is Active in Pharmaco-Resistant Models of Epilepsy and Reduces Hyperexcitability after Traumatic Brain Injury

Rapid tolerance to behavioral effects of ethanol in rats: Prevention by R-(−)-ketamine

N-Substituted-3-alkoxy-derivatives of dextromethorphan are functional NMDA receptor antagonists in vivo: Evidence from an NMDA-induced seizure model in rats

AMPA receptors play an important role in the biological consequences of spinal cord injury: Implications for AMPA receptor modulators for therapeutic benefit

A Maximum Entropy Model Applied to Spatial and Temporal Correlations from Cortical Networks In Vitro

Structural Analogs of the GABAkine KRM-II-81 Are Orally Bioavailable Anticonvulsants without Sedation

Long-term outcome in children with moyamoya syndrome after cranial revascularization by pial synangiosis

Pineal gland hypermetabolic involvement without central nervous system symptoms in a pediatric patient with primary nodular sclerosis subtype classical Hodgkin Lymphoma

Reduction in Overt and Silent Stroke Recurrence Rate Following Cerebral Revascularization Surgery in Children with Sickle Cell Disease and Severe Cerebral Vasculopathy

The value of human epileptic tissue in the characterization and development of novel antiepileptic drugs: The example of CERC-611 and KRM-II-81

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