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Genetic polymorphisms in xenobiotic metabolism

European journal of cancer (1990), 1994, Vol.30 (13), p.1921-1935

1994

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Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema

The Lancet (British edition), 1997-08, Vol.350 (9078), p.630-633

1997

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Polymorphism in serotonin transporter gene associated with susceptibility to major depression

The Lancet (British edition), 1996-03, Vol.347 (9003), p.731-733

1996

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Induction of γ-glutamylcysteine synthetase by cigarette smoke is associated with AP-1 in human alveolar epithelial cells

FEBS letters, 1996-10, Vol.396 (1), p.21-25

1996

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Characterisation of gamma-glutamylcysteine synthetase-heavy subunit promoter: a critical role for AP-1

FEBS letters, 1998-05, Vol.427 (1), p.129

1998

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Transcriptional Regulation of γ-Glutamylcysteine Synthetase-Heavy Subunit by Oxidants in Human Alveolar Epithelial Cells

Biochemical and biophysical research communications, 1996-12, Vol.229 (3), p.832-837

1996

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Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease

The Lancet (British edition), 1992-06, Vol.339 (8806), p.1375-1377

1992

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Microsomal epoxide hydrolase gene polymorphism and susceptibility to colon cancer

British journal of cancer, 1999-01, Vol.79 (1), p.168-171

1999

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A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid

Journal of medical genetics, 1997-09, Vol.34 (9), p.758-760

1997

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Characterization of the human cytochrome P4502D6 promoter. A potential role for antagonistic interactions between members of the nuclear receptor family

The Journal of biological chemistry, 1996-10, Vol.271 (41), p.25269-25276

1996

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Altered Allelic Distributions of the Serotonin Transporter Gene in Migraine Without Aura and Migraine with Aura

Cephalalgia, 1998-01, Vol.18 (1), p.23-26

1998

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Multiple cutaneous basal cell carcinomas: glutathione S-transferase (GSTM1, GSTT1) and cytochrome P450 (CYP2D6, CYP1A1) polymorphisms influence tumour numbers and accrual

Carcinogenesis (New York), 1996-09, Vol.17 (9), p.1891-1896

1996

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Frequency of glutathione S-transferase M1 deletion in smokers with emphysema and lung cancer

Human & experimental toxicology, 1997-07, Vol.16 (7), p.356-360

1997

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N-acetyltransferase 2 genotype in colorectal cancer and selective gene retention in cancers with chromosome 8p deletions

Gut, 1997-08, Vol.41 (2), p.229-234

1997

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Polymorphisms of the gene for microsomal epoxide hydrolase and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a Caucasian population

Toxicology letters, 2000-04, Vol.115 (1), p.17-22

2000

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Relationship between the debrisoquine hydroxylase polymorphism and cancer susceptibility

Carcinogenesis (New York), 1992-06, Vol.13 (6), p.1035-1038

1992

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Heterogeneous expression and polymorphic genotype of glutathione S-transferases in human lung

Thorax, 1994-10, Vol.49 (10), p.1010-1014

1994

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Structure of a variable number tandem repeat of the serotonin transporter gene and association with affective disorder

Psychiatric genetics, 1996, Vol.6 (4), p.177-182

1996

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CYP2D6 polymorphisms in Alzheimer's disease, with and without extrapyramidal signs, showing no apolipoprotein E epsilon 4 effect modification

Biological psychiatry (1969), 1999-02, Vol.45 (4), p.426-429

1999

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Association of short alleles of a VNTR of the serotonin transporter gene with anxiety symptoms in patients presenting after deliberate self harm

Neuropharmacology, 1997-04, Vol.36 (4-5), p.439-443

1997

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Polymorphisms in drug-metabolizing enzymes as modifiers of cancer risk

Clinical chemistry (Baltimore, Md.), 1995-12, Vol.41 (12 Pt 2), p.1864-1869

1995

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N-acetyl transferase 1 : two polymorphisms in coding sequence identified in colorectal cancer patients

British journal of cancer, 1998-03, Vol.77 (6), p.913-916

1998

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Metabolic polymorphisms in carcinogen metabolising enzymes and cancer susceptibility

British medical bulletin, 1994-07, Vol.50 (3), p.718-731

1994

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Molecular Genetic Analysis of the Cytochrome P450-Debrisoquine Hydroxylase Locus and Association with Cancer Susceptibility

Environmental health perspectives, 1992-11, Vol.98, p.107-112

1992

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Evidence for a role of cytochrome P450 2D6 and 3A4 in ethylmorphine metabolism

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1995-01, Vol.39 (1), p.77-80

1995

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Genetic polymorphisms in xenobiotic metabolism

Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema

Polymorphism in serotonin transporter gene associated with susceptibility to major depression

Induction of γ-glutamylcysteine synthetase by cigarette smoke is associated with AP-1 in human alveolar epithelial cells

Characterisation of gamma-glutamylcysteine synthetase-heavy subunit promoter: a critical role for AP-1

Transcriptional Regulation of γ-Glutamylcysteine Synthetase-Heavy Subunit by Oxidants in Human Alveolar Epithelial Cells

Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease

Microsomal epoxide hydrolase gene polymorphism and susceptibility to colon cancer

A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid

Characterization of the human cytochrome P4502D6 promoter. A potential role for antagonistic interactions between members of the nuclear receptor family

Altered Allelic Distributions of the Serotonin Transporter Gene in Migraine Without Aura and Migraine with Aura

Multiple cutaneous basal cell carcinomas: glutathione S-transferase (GSTM1, GSTT1) and cytochrome P450 (CYP2D6, CYP1A1) polymorphisms influence tumour numbers and accrual

Frequency of glutathione S-transferase M1 deletion in smokers with emphysema and lung cancer

N-acetyltransferase 2 genotype in colorectal cancer and selective gene retention in cancers with chromosome 8p deletions

Polymorphisms of the gene for microsomal epoxide hydrolase and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a Caucasian population

Relationship between the debrisoquine hydroxylase polymorphism and cancer susceptibility

Heterogeneous expression and polymorphic genotype of glutathione S-transferases in human lung

Structure of a variable number tandem repeat of the serotonin transporter gene and association with affective disorder

CYP2D6 polymorphisms in Alzheimer's disease, with and without extrapyramidal signs, showing no apolipoprotein E epsilon 4 effect modification

Association of short alleles of a VNTR of the serotonin transporter gene with anxiety symptoms in patients presenting after deliberate self harm

Polymorphisms in drug-metabolizing enzymes as modifiers of cancer risk

N-acetyl transferase 1 : two polymorphisms in coding sequence identified in colorectal cancer patients

Metabolic polymorphisms in carcinogen metabolising enzymes and cancer susceptibility

Molecular Genetic Analysis of the Cytochrome P450-Debrisoquine Hydroxylase Locus and Association with Cancer Susceptibility

Evidence for a role of cytochrome P450 2D6 and 3A4 in ethylmorphine metabolism

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