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Human iPSC-derived cardiomyocytes and tissue engineering strategies for disease modeling and drug screening

Biotechnology advances, 2017-01, Vol.35 (1), p.77-94

2017

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Nanotopography-Induced Structural Anisotropy and Sarcomere Development in Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells

ACS applied materials & interfaces, 2016-08, Vol.8 (34), p.21923-21932

2016

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Spatiotemporal control of cardiac anisotropy using dynamic nanotopographic cues

Biomaterials, 2016-04, Vol.86, p.1-10

2016

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Tunable electroconductive decellularized extracellular matrix hydrogels for engineering human cardiac microphysiological systems

Biomaterials, 2021-05, Vol.272, p.120764-120764, Article 120764

2021

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Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs

Scientific reports, 2016-02, Vol.6 (1), p.20030, Article 20030

2016

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How multi-organ microdevices can help foster drug development

Advanced drug delivery reviews, 2014-04, Vol.69-70, p.158-169

2014

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Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy

The Journal of cell biology, 2019-09, Vol.218 (9), p.2919-2944

2019

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Biomimetic 3D Tissue Models for Advanced High-Throughput Drug Screening

Journal of Laboratory Automation, 2015-06, Vol.20 (3), p.201-215

2015

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Advances and Current Challenges Associated with the Use of Human Induced Pluripotent Stem Cells in Modeling Neurodegenerative Disease

Cells, tissues, organs, 2018-01, Vol.205 (5-6), p.331-349

2018

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Muscular dystrophy in a dish: engineered human skeletal muscle mimetics for disease modeling and drug discovery

Drug discovery today, 2016-09, Vol.21 (9), p.1387-1398

2016

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Nanopatterned Nafion Microelectrode Arrays for In Vitro Cardiac Electrophysiology

Advanced functional materials, 2020-06, Vol.30 (25), p.n/a

2020

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Regulation of skeletal myotube formation and alignment by nanotopographically controlled cell‐secreted extracellular matrix

Journal of biomedical materials research. Part A, 2018-06, Vol.106 (6), p.1543-1551

2018

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Creating Interactions between Tissue-Engineered Skeletal Muscle and the Peripheral Nervous System

Cells, tissues, organs, 2016, Vol.202 (3-4), p.143-158

2016

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Morphological and functional characterization of human induced pluripotent stem cell-derived neurons (iCell Neurons) in defined culture systems

Biotechnology progress, 2015-11, Vol.31 (6), p.1613-1622

2015

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Conformational sampling of CMT-2D associated GlyRS mutations

Brain multiphysics, 2022, Vol.3, p.100054, Article 100054

2022

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Charcot‐Marie‐Tooth Disease Type 4H Resulting from Compound Heterozygous Mutations in FGD4 from Nonconsanguineous Korean Families

Annals of human genetics, 2015-11, Vol.79 (6), p.460-469

2015

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Human Motor Neurons Elicit Pathological Hallmarks of ALS and Reveal Potential Biomarkers of the Disease in Response to Prolonged IFNγ Exposure

The Journal of neuroscience, 2024-04, Vol.44 (16)

2024

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Micro- and nano-patterned conductive graphene-PEG hybrid scaffolds for cardiac tissue engineering

Chemical communications (Cambridge, England), 2017-06, Vol.53 (53), p.7412-7415

2017

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Engineering anisotropic 3D tubular tissues with flexible thermoresponsive nanofabricated substrates

Biomaterials, 2020-05, Vol.240, p.119856-119856, Article 119856

2020

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Creating stem cell‐derived neuromuscular junctions in vitro

Muscle & nerve, 2021-10, Vol.64 (4), p.388-403

2021

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Characterizing the functional impact of embryonic myosin mutations in stem cell-derived skeletal muscle

Biophysical journal, 2023-02, Vol.122 (3), p.149a-149a

2023

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The Role of Connective Tissue and Extracellular Matrix Signaling in Controlling Muscle Development, Function, and Response to Mechanical Forces

Seminars in orthodontics, 2010-06, Vol.16 (2), p.135-142

2010

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High‐precision and Scalable Fabrication of Biomimetic Culture Environments for Replicating the Extracellular Matrix In Vitro

The FASEB journal, 2021-05, Vol.35 (S1), p.n/a, Article fasebj.2021.35.S1.03234

2021

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NanoMEA: A Tool for High-Throughput, Electrophysiological Phenotyping of Patterned Excitable Cells

Nano letters, 2020-03, Vol.20 (3), p.1561-1570

2020

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Astrocyte-derived extracellular vesicles enhance the survival and electrophysiological function of human cortical neurons in vitro

Biomaterials, 2021-04, Vol.271, p.120700-120700, Article 120700

2021

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Human iPSC-derived cardiomyocytes and tissue engineering strategies for disease modeling and drug screening

Nanotopography-Induced Structural Anisotropy and Sarcomere Development in Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells

Spatiotemporal control of cardiac anisotropy using dynamic nanotopographic cues

Tunable electroconductive decellularized extracellular matrix hydrogels for engineering human cardiac microphysiological systems

Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs

How multi-organ microdevices can help foster drug development

Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy

Biomimetic 3D Tissue Models for Advanced High-Throughput Drug Screening

Advances and Current Challenges Associated with the Use of Human Induced Pluripotent Stem Cells in Modeling Neurodegenerative Disease

Muscular dystrophy in a dish: engineered human skeletal muscle mimetics for disease modeling and drug discovery

Nanopatterned Nafion Microelectrode Arrays for In Vitro Cardiac Electrophysiology

Regulation of skeletal myotube formation and alignment by nanotopographically controlled cell‐secreted extracellular matrix

Creating Interactions between Tissue-Engineered Skeletal Muscle and the Peripheral Nervous System

Morphological and functional characterization of human induced pluripotent stem cell-derived neurons (iCell Neurons) in defined culture systems

Conformational sampling of CMT-2D associated GlyRS mutations

Charcot‐Marie‐Tooth Disease Type 4H Resulting from Compound Heterozygous Mutations in FGD4 from Nonconsanguineous Korean Families

Human Motor Neurons Elicit Pathological Hallmarks of ALS and Reveal Potential Biomarkers of the Disease in Response to Prolonged IFNγ Exposure

Micro- and nano-patterned conductive graphene-PEG hybrid scaffolds for cardiac tissue engineering

Engineering anisotropic 3D tubular tissues with flexible thermoresponsive nanofabricated substrates

Creating stem cell‐derived neuromuscular junctions in vitro

Characterizing the functional impact of embryonic myosin mutations in stem cell-derived skeletal muscle

The Role of Connective Tissue and Extracellular Matrix Signaling in Controlling Muscle Development, Function, and Response to Mechanical Forces

High‐precision and Scalable Fabrication of Biomimetic Culture Environments for Replicating the Extracellular Matrix In Vitro

NanoMEA: A Tool for High-Throughput, Electrophysiological Phenotyping of Patterned Excitable Cells

Astrocyte-derived extracellular vesicles enhance the survival and electrophysiological function of human cortical neurons in vitro

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