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Bridging the translational innovation gap through good biomarker practice

Nature reviews. Drug discovery, 2017-09, Vol.16 (9), p.587-588

2017

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Increased Hepatobiliary and Fecal Cholesterol Excretion upon Activation of the Liver X Receptor Is Independent of ABCA1

The Journal of biological chemistry, 2002-09, Vol.277 (37), p.33870-33877

2002

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Nonpeptidergic allosteric antagonists differentially bind to the CXCR2 chemokine receptor

The Journal of pharmacology and experimental therapeutics, 2009-05, Vol.329 (2), p.783-790

2009

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Liver receptor homolog‐1 is critical for adequate up‐regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration

Hepatology (Baltimore, Md.), 2011-06, Vol.53 (6), p.2075-2085

2011

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Elimination of macrophages drives LXR-induced regression both in initial and advanced stages of atherosclerotic lesion development

Biochemical pharmacology, 2013-12, Vol.86 (11), p.1594-1602

2013

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A signaling-selective, nanomolar potent allosteric low molecular weight agonist for the human luteinizing hormone receptor

Naunyn-Schmiedeberg's archives of pharmacology, 2008-11, Vol.378 (5), p.503-514

2008

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Tibolone prevents atherosclerotic lesion formation in cholesterol-fed, ovariectomized rabbits

Arteriosclerosis, thrombosis, and vascular biology, 1998-12, Vol.18 (12), p.1844-1854

1998

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Unique Overlap in the Prerequisites for Thrombin Inhibition and Oral Bioavailability Resulting in Potent Oral Antithrombotics

Journal of medicinal chemistry, 2002-09, Vol.45 (20), p.4419-4432

2002

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Uniform procedure of (1)H NMR analysis of rat urine and toxicometabonomics Part II: comparison of NMR profiles for classification of hepatotoxicity

Toxicological sciences, 2007-07, Vol.98 (1), p.286

2007

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Differences in propionate-induced inhibition of cholesterol and triacylglycerol synthesis between human and rat hepatocytes in primary culture

British journal of nutrition, 1995-08, Vol.74 (2), p.197-207

1995

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Sensitivity of super(1)H NMR Analysis of Rat Urine in Relation to Toxicometabonomics. Part I: Dose-Dependent Toxic Effects of Bromobenzene and Paracetamol

Toxicological sciences, 2007-07, Vol.98 (1), p.271-285

2007

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Uniform Procedure of super(1)H NMR Analysis of Rat Urine and Toxicometabonomics Part II: Comparison of NMR Profiles for Classification of Hepatotoxicity

Toxicological sciences, 2007-07, Vol.98 (1), p.286-297

2007

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Sensitivity of 1H NMR Analysis of Rat Urine in Relation to Toxicometabonomics. Part I: Dose-Dependent Toxic Effects of Bromobenzene and Paracetamol

Toxicological sciences, 2007-07, Vol.98 (1), p.271-285

2007

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Uniform Procedure of 1H NMR Analysis of Rat Urine and Toxicometabonomics Part II: Comparison of NMR Profiles for Classification of Hepatotoxicity

Toxicological sciences, 2007-07, Vol.98 (1), p.286-297

2007

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Sensitivity of (1)H NMR analysis of rat urine in relation to toxicometabonomics. Part I: dose-dependent toxic effects of bromobenzene and paracetamol

Toxicological sciences, 2007-07, Vol.98 (1), p.271

2007

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Comparison of the antiatherosclerotic effect of tibolone with that of estradiol and ethinyl estradiol in cholesterol-fed, ovariectomized rabbits

Menopause (New York, N.Y.), 2001-03, Vol.8 (2), p.96-105

2001

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Dietary fish oil-induced changes in intrahepatic cholesterol transport and bile acid synthesis in rats

The Journal of clinical investigation, 1991-09, Vol.88 (3), p.943-951

1991

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Effects of dietary cholesterol on bile formation and hepatic processing of chylomicron remnant cholesterol in the rat

Hepatology (Baltimore, Md.), 1993-03, Vol.17 (3), p.445-454

1993

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Differential effects of eicosapentaenoic acid on glycerolipid and apolipoprotein B metabolism in primary human hepatocytes compared to HepG2 cells and primary rat hepatocytes

Biochimica et biophysica acta, 1995-04, Vol.1256 (1), p.88-96

1995

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Effects of dietary cholesterol on bile formation and hepatic processing of chylomicron remnant cholesterol in the rat

Hepatology (Baltimore, Md.), 1993-03, Vol.17 (3), p.445-454

1993

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Dietary cholesterol-induced down-regulation of intestinal 3-hydroxy-3-methylglutaryl coenzyme a reductase activity is diminished in rabbits with hyperresponse of serum cholesterol to dietary cholesterol

The Journal of nutrition, 1993-04, Vol.123 (4), p.695-703

1993

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Infection of mice with lactate dehydrogenase—elevating virus destroys the subpopulation of kupffer cells involved in receptor‐mediated endocytosis of lactate dehydrogenase and other enzymes

Hepatology (Baltimore, Md.), 1990-11, Vol.12 (5), p.1192-1199

1990

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Dietary Cholesterol-Induced Down-Regulation of Intestinal 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity Is Diminished in Rabbits with Hyperresponse of Serum Cholesterol to Dietary Cholesterol1

The Journal of nutrition, 1993-04, Vol.123 (4), p.695-703

1993

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Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

Molecular psychiatry, 2012-01, Vol.17 (1), p.36-48

2012

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Bridging the translational innovation gap through good biomarker practice

Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index

Increased Hepatobiliary and Fecal Cholesterol Excretion upon Activation of the Liver X Receptor Is Independent of ABCA1

Nonpeptidergic allosteric antagonists differentially bind to the CXCR2 chemokine receptor

Liver receptor homolog‐1 is critical for adequate up‐regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration

Elimination of macrophages drives LXR-induced regression both in initial and advanced stages of atherosclerotic lesion development

A signaling-selective, nanomolar potent allosteric low molecular weight agonist for the human luteinizing hormone receptor

Tibolone prevents atherosclerotic lesion formation in cholesterol-fed, ovariectomized rabbits

Unique Overlap in the Prerequisites for Thrombin Inhibition and Oral Bioavailability Resulting in Potent Oral Antithrombotics

Uniform procedure of (1)H NMR analysis of rat urine and toxicometabonomics Part II: comparison of NMR profiles for classification of hepatotoxicity

Differences in propionate-induced inhibition of cholesterol and triacylglycerol synthesis between human and rat hepatocytes in primary culture

Sensitivity of super(1)H NMR Analysis of Rat Urine in Relation to Toxicometabonomics. Part I: Dose-Dependent Toxic Effects of Bromobenzene and Paracetamol

Uniform Procedure of super(1)H NMR Analysis of Rat Urine and Toxicometabonomics Part II: Comparison of NMR Profiles for Classification of Hepatotoxicity

Sensitivity of 1H NMR Analysis of Rat Urine in Relation to Toxicometabonomics. Part I: Dose-Dependent Toxic Effects of Bromobenzene and Paracetamol

Uniform Procedure of 1H NMR Analysis of Rat Urine and Toxicometabonomics Part II: Comparison of NMR Profiles for Classification of Hepatotoxicity

Sensitivity of (1)H NMR analysis of rat urine in relation to toxicometabonomics. Part I: dose-dependent toxic effects of bromobenzene and paracetamol

Comparison of the antiatherosclerotic effect of tibolone with that of estradiol and ethinyl estradiol in cholesterol-fed, ovariectomized rabbits

Dietary fish oil-induced changes in intrahepatic cholesterol transport and bile acid synthesis in rats

Effects of dietary cholesterol on bile formation and hepatic processing of chylomicron remnant cholesterol in the rat

Differential effects of eicosapentaenoic acid on glycerolipid and apolipoprotein B metabolism in primary human hepatocytes compared to HepG2 cells and primary rat hepatocytes

Effects of dietary cholesterol on bile formation and hepatic processing of chylomicron remnant cholesterol in the rat

Dietary cholesterol-induced down-regulation of intestinal 3-hydroxy-3-methylglutaryl coenzyme a reductase activity is diminished in rabbits with hyperresponse of serum cholesterol to dietary cholesterol

Infection of mice with lactate dehydrogenase—elevating virus destroys the subpopulation of kupffer cells involved in receptor‐mediated endocytosis of lactate dehydrogenase and other enzymes

Dietary Cholesterol-Induced Down-Regulation of Intestinal 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity Is Diminished in Rabbits with Hyperresponse of Serum Cholesterol to Dietary Cholesterol1

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

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