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Component-based syntheses of trioxacarcin A, DC-45-A1 and structural analogues

Nature chemistry, 2013-10, Vol.5 (10), p.886-893

2013

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Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-Life

ACS medicinal chemistry letters, 2023-10, Vol.14 (10), p.1427-1433

2023

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Scalable Synthesis of Enantiomerically Pure syn-2,3-Dihydroxybutyrate by Sharpless Asymmetric Dihydroxylation of p-Phenylbenzyl Crotonate

Journal of organic chemistry, 2011-10, Vol.76 (20), p.8554-8559

2011

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Crystalline guanine adducts of natural and synthetic trioxacarcins suggest a common biological mechanism and reveal a basis for the instability of trioxacarcin A

Bioorganic & medicinal chemistry letters, 2014-09, Vol.24 (18), p.4410-4413

2014

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Diastereoselective Additions of Allylmetal Reagents to Free and Protected syn-α,β-Dihydroxyketones Enable Efficient Synthetic Routes to Methyl Trioxacarcinoside A

Organic letters, 2012-04, Vol.14 (7), p.1812-1815

2012

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Synthesis and Antitubercular Activities in Vitro of New p-Aminosalicylic Ester Imines

Letters in drug design & discovery, 2014-01, Vol.11 (8), p.953-959

2014

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Early Drug-Induced Liver Injury Risk Screening: “Free,” as Good as It Gets

Toxicological sciences, 2022-07, Vol.188 (2), p.208-218

2022

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Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure–Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H 1 Receptor Inverse Agonist

Journal of medicinal chemistry, 2020-07, Vol.63 (13), p.7268-7292

2020

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Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure–Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H1 Receptor Inverse Agonist

Journal of medicinal chemistry, 2020-07, Vol.63 (13), p.7268-7292

2020

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Novel advances in biotransformation and bioactivation research - 2020 year in review

Drug metabolism reviews, 2021-07, Vol.53 (3), p.384-433

2021

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Component-Based Syntheses of Trioxacarcins

Smaltz, Daniel J

2014

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Quantifying the economic impact of communication inefficiencies in U.S. hospitals

Journal of healthcare management, 2010-07, Vol.55 (4), p.265-282

2010

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Component-based syntheses of trioxacarcin A, DC-45-A1 and structural analogues

Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-Life

Scalable Synthesis of Enantiomerically Pure syn-2,3-Dihydroxybutyrate by Sharpless Asymmetric Dihydroxylation of p-Phenylbenzyl Crotonate

Crystalline guanine adducts of natural and synthetic trioxacarcins suggest a common biological mechanism and reveal a basis for the instability of trioxacarcin A

Diastereoselective Additions of Allylmetal Reagents to Free and Protected syn-α,β-Dihydroxyketones Enable Efficient Synthetic Routes to Methyl Trioxacarcinoside A

Synthesis and Antitubercular Activities in Vitro of New p-Aminosalicylic Ester Imines

Early Drug-Induced Liver Injury Risk Screening: “Free,” as Good as It Gets

Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure–Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H 1 Receptor Inverse Agonist

Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure–Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H1 Receptor Inverse Agonist

Novel advances in biotransformation and bioactivation research - 2020 year in review

Late Stage Lead Diversification (LSLD) Coupled with Quantitative NMR Spectroscopy to Identify New SAR Vectors at Nanomole Scale Synthesis: Application to Loratadine a Human Histamine H 1 Receptor Inverse Agonist

Component-Based Syntheses of Trioxacarcins

Quantifying the economic impact of communication inefficiencies in U.S. hospitals

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