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Phosphorus-containing inhibitors of HMG-CoA reductase. 2. Synthesis and biological activities of a series of substituted pyridines containing a hydroxyphosphinyl moiety

Journal of medicinal chemistry, 1991-09, Vol.34 (9), p.2804-2815

1991

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Enantioselective Synthesis of α-Phosphono Sulfonate Squalene Synthase Inhibitors: Chiral Recognition in the Interactions of an α-Phosphono Sulfonate Inhibitor with Squalene Synthase

Journal of the American Chemical Society, 1996-11, Vol.118 (46), p.11668-11669

1996

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1,1-Bisphosphonate Squalene Synthase Inhibitors: Interplay Between the Isoprenoid Subunit and the Diphosphate Surrogate

Journal of medicinal chemistry, 1995-07, Vol.38 (14), p.2596-2605

1995

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Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo

The Journal of biological chemistry, 1993-11, Vol.268 (33), p.24832-24837

1993

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Aromatic isosteres as conformational probes for an isoprenyl subunit: application to inhibitors of squalene synthase

Bioorganic & medicinal chemistry letters, 1993-04, Vol.3 (4), p.595-600

1993

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Discovery, synthesis, and structure–activity studies of tetrazole based growth hormone secretagogues

Bioorganic & medicinal chemistry letters, 2007-11, Vol.17 (21), p.5928-5933

2007

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Discovery of a Potent and Novel Motilin Agonist

Journal of medicinal chemistry, 2004-03, Vol.47 (7), p.1704-1708

2004

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Tetrahydroisoquinoline 1-carboxamides as growth hormone secretagogues

Bioorganic & medicinal chemistry letters, 2005-04, Vol.15 (7), p.1799-1802

2005

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( d)-2- tert-Butoxycarbonylamino-5,5-difluoro-5-phenyl-pentanoic acid: Synthesis and incorporation into the growth hormone secretagogues

Bioorganic & medicinal chemistry, 2008-07, Vol.18 (14), p.4072-4074

2008

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Design and synthesis of tetrazole-based growth hormone secretagogue: The SAR studies of the O-benzyl serine side chain

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (6), p.1825-1829

2008

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Tetrazole based amides as growth hormone secretagogues

Bioorganic & medicinal chemistry, 2008-04, Vol.18 (8), p.2536-2539

2008

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Discovery and optimization of ( R)-prolinol-derived agonists of the Growth Hormone Secretagogue receptor (GHSR)

Bioorganic & medicinal chemistry, 2008-09, Vol.18 (18), p.5083-5086

2008

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Optimization of 1H-tetrazole-1-alkanenitriles as potent orally bioavailable growth hormone secretagogues

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (6), p.2067-2072

2008

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Optimization of 1 H-tetrazole-1-alkanenitriles as potent orally bioavailable growth hormone secretagogues

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (6), p.2067-2072

2008

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MURACEINS-MURAMYL PEPTIDES PRODUCED BY NOCARDIA ORIENTALIS AS ANGIOTENSIN-CONVERTING ENZYME INHIBITORS: I. TAXONOMY, FERMENTATION AND BIOLOGICAL PROPERTIES

The Journal of Antibiotics, 1984, Vol.37(4), pp.330-335

1984

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CATACANDINS, NOVEL ANTICANDIDAL ANTIBIOTICS OF BACTERIAL ORIGIN

The Journal of Antibiotics, 1985, Vol.38(12), pp.1642-1648

1985

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Phenacein: an angiotensin-converting enzyme inhibitor produced by a streptomycete. I: Taxonomy, fermentation and biological properties

Journal of antibiotics, 1984, Vol.37 (11), p.1308-1312

1984

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IONOMYCIN, A NEW POLYETHER ANTIBIOTIC

The Journal of Antibiotics, 1978, Vol.31(9), pp.815-819

1978

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Activity of sulfa drugs and dihydrofolate reductase inhibitors against Candida albicans

Experientia, 1982-04, Vol.38 (4), p.436-437

1982

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ISOLATION, CHARACTERIZATION, AND STRUCTURE OF RABELOMYCIN, A NEW ANTIBIOTIC

The Journal of Antibiotics, 1970, Vol.23(9), pp.437-441

1970

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JANIEMYCIN, A NEW PEPTIDE ANTIBIOTIC

The Journal of Antibiotics, 1970, Vol.23(10), pp.502-507

1970

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THE DIUMYCINS: NEW MEMBERS OF AN ANTIBIOTIC FAMILY HAVING PROLONGED IN VIVO ACTIVITY

The Journal of Antibiotics, 1969/10/25, Vol.22(10), pp.490-493

1969

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PHENACEIN-AN ANGIOTENSIN-CONVERTING ENZYME INHIBITOR PRODUCED BY A STREPTOMYCETE: I.TAXONOMY, FERMENTATION AND BIOLOGICAL PROPERTIES

The Journal of Antibiotics, 1984, Vol.37(11), pp.1308-1312

1984

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EM49, A NEW PEPTIDE ANTIBIOTIC: III. BIOLOGICAL CHARACTERIZATION IN VITRO AND IN VIVO

The Journal of Antibiotics, 1973/08/25, Vol.26(8), pp.457-462

1973

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Discovery of a Tetrazole-Based Growth Hormone Secretagogue: 4-(Hydroxybutyl)carbamic Acid 2-{5-[1-(2-Amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl Ester (BMS-317180)

Phosphorus-containing inhibitors of HMG-CoA reductase. 2. Synthesis and biological activities of a series of substituted pyridines containing a hydroxyphosphinyl moiety

Enantioselective Synthesis of α-Phosphono Sulfonate Squalene Synthase Inhibitors: Chiral Recognition in the Interactions of an α-Phosphono Sulfonate Inhibitor with Squalene Synthase

1,1-Bisphosphonate Squalene Synthase Inhibitors: Interplay Between the Isoprenoid Subunit and the Diphosphate Surrogate

Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo

Aromatic isosteres as conformational probes for an isoprenyl subunit: application to inhibitors of squalene synthase

Discovery, synthesis, and structure–activity studies of tetrazole based growth hormone secretagogues

Discovery of a Potent and Novel Motilin Agonist

Tetrahydroisoquinoline 1-carboxamides as growth hormone secretagogues

( d)-2- tert-Butoxycarbonylamino-5,5-difluoro-5-phenyl-pentanoic acid: Synthesis and incorporation into the growth hormone secretagogues

Design and synthesis of tetrazole-based growth hormone secretagogue: The SAR studies of the O-benzyl serine side chain

Tetrazole based amides as growth hormone secretagogues

Discovery and optimization of ( R)-prolinol-derived agonists of the Growth Hormone Secretagogue receptor (GHSR)

Optimization of 1H-tetrazole-1-alkanenitriles as potent orally bioavailable growth hormone secretagogues

Optimization of 1 H-tetrazole-1-alkanenitriles as potent orally bioavailable growth hormone secretagogues

MURACEINS-MURAMYL PEPTIDES PRODUCED BY NOCARDIA ORIENTALIS AS ANGIOTENSIN-CONVERTING ENZYME INHIBITORS: I. TAXONOMY, FERMENTATION AND BIOLOGICAL PROPERTIES

CATACANDINS, NOVEL ANTICANDIDAL ANTIBIOTICS OF BACTERIAL ORIGIN

Phenacein: an angiotensin-converting enzyme inhibitor produced by a streptomycete. I: Taxonomy, fermentation and biological properties

IONOMYCIN, A NEW POLYETHER ANTIBIOTIC

Activity of sulfa drugs and dihydrofolate reductase inhibitors against Candida albicans

ISOLATION, CHARACTERIZATION, AND STRUCTURE OF RABELOMYCIN, A NEW ANTIBIOTIC

JANIEMYCIN, A NEW PEPTIDE ANTIBIOTIC

THE DIUMYCINS: NEW MEMBERS OF AN ANTIBIOTIC FAMILY HAVING PROLONGED IN VIVO ACTIVITY

PHENACEIN-AN ANGIOTENSIN-CONVERTING ENZYME INHIBITOR PRODUCED BY A STREPTOMYCETE: I.TAXONOMY, FERMENTATION AND BIOLOGICAL PROPERTIES

EM49, A NEW PEPTIDE ANTIBIOTIC: III. BIOLOGICAL CHARACTERIZATION IN VITRO AND IN VIVO

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