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N,N′-Dialkylaminoalkylcarbonyl (DAAC) prodrugs and aminoalkylcarbonyl (AAC) prodrugs of 4-hydroxyacetanilide and naltrexone with improved skin permeation properties

Bioorganic & medicinal chemistry letters, 2011-07, Vol.21 (13), p.4078-4082

2011

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A correlation of flux through a silicone membrane with flux through hairless mouse skin and human skin in vitro

International journal of pharmaceutics, 2009-05, Vol.373 (1), p.62-67

2009

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Synthesis and topical delivery of N-alkyl- N-alkyloxycarbonylaminomethyl prodrugs of a model phenolic drug: Acetaminophen

International journal of pharmaceutics, 2007-06, Vol.337 (1), p.48-55

2007

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Topical delivery of N-alkyl- N-alkyloxycarbonylaminomethyl (NANAOCAM) prodrugs of theophylline (ThH)

International journal of pharmaceutics, 2007-03, Vol.332 (1), p.64-71

2007

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Synthesis of soft alkyl phenolic ether prodrugs using Mitsunobu chemistry

Tetrahedron letters, 2006-12, Vol.47 (50), p.8981-8982

2006

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A comparison of the fit of flux through hairless mouse skin from water data to three model equations

International journal of pharmaceutics, 2009-01, Vol.366 (1), p.65-73

2009

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α-(1 H-Imidazol-1-yl)alkyl (IMIDA) carboxylic acid esters as prodrugs of carboxylic acid containing drugs

Tetrahedron letters, 2007-06, Vol.48 (26), p.4609-4611

2007

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Phenytoin Prodrugs III: Water-Soluble Prodrugs for Oral and/or Parenteral Use

Journal of pharmaceutical sciences, 1984-08, Vol.73 (8), p.1068-1073

1984

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Prodrugs of 6-Thiopurines: Enhanced Delivery Through the Skin

Journal of pharmaceutical sciences, 1983-04, Vol.72 (4), p.372-378

1983

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Transdermal delivery of theophylline from alcohol vehicles

International journal of pharmaceutics, 1998-09, Vol.171 (2), p.185-193

1998

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Alcohol flux and effect on the delivery of theophylline from propylene glycol

International journal of pharmaceutics, 1997-10, Vol.156 (1), p.17-26

1997

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Degradation of aspartame in acidic aqueous media and its stabilization by complexation with cyclodextrins or modified cyclodextrins

International journal of pharmaceutics, 1992-12, Vol.88 (1), p.189-199

1992

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Transdermal delivery of 5-fluorouracil (5-FU) through hairless mouse skin by 1-alkylaminocarbonyl-5-FU prodrugs: Physicochemical characterization of prodrugs and correlations with transdermal delivery

International journal of pharmaceutics, 1993-05, Vol.93 (1), p.27-36

1993

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The estimation of relative water solubility for prodrugs that are unstable in water

International journal of pharmaceutics, 1993-05, Vol.93 (1), p.37-47

1993

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Microcalorimetric study of the interactions of aspartame with β-cyclodextrin and hydroxypropyl-β-cyclodextrin: The anamalous heat of dilution of the latter

International journal of pharmaceutics, 1992-10, Vol.86 (2), p.263-265

1992

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Hydroxymethyl and acyloxymethyl prodrugs of theophylline: enhanced delivery of polar drugs through skin

International journal of pharmaceutics, 1982-01, Vol.12 (4), p.299-313

1982

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Improved delivery through biological membranes. XII. The effect of the incorporation of biphasic solubilizing groups into prodrugs of steroids

International journal of pharmaceutics, 1983, Vol.15 (3), p.235-250

1983

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The effect of aminomethyl (N-Mannich base) derivatization on the ability of S 6-pivaloyloxymethyl-6-mercaptopurine prodrug to deliver 6-mercaptopurine through hairless mouse skin

International journal of pharmaceutics, 1989-12, Vol.57 (3), p.253-261

1989

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The effect of aminomethyl(N-Manich base) derivatization on the ability of S6-pivaloyloxymethyl-6-mercaptopurine prodrug to deliver 6-mercaptopurine through hairless mouse skin

International journal of pharmaceutics, 1989-12, Vol.57 (3), p.253-261

1989

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Mannich base derivatives of theophylline and 5-fluorouracil: syntheses, properties and topical delivery characteristics

International journal of pharmaceutics, 1984-01, Vol.21 (3), p.251-264

1984

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13C NMR spectroscopy of 4,5- and 5,6-double bond isomers of spiro-3-steroidal ketone derivatives

Tetrahedron, 1981-01, Vol.37 (20), p.3467-3471

1981

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13C NMR spectroscopy of 4,5- and 5,6-double bond isomers of spiro-3-steroidal ketone derivatives : The determination of the structures of steroidal thiazolidines

Tetrahedron, 1981, Vol.37 (20), p.3467-3471

1981

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Acylation of the 4,5- and 5,6-double bond isomers of 3-steroidal thiazolidines

Tetrahedron, 1981-01, Vol.37 (20), p.3463-3466

1981

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Acyloxyamines as Prodrugs of Anti-inflammatory Carboxylic Acids for Improved Delivery Through Skin

Journal of pharmaceutical sciences, 1984-12, Vol.73 (12), p.1734-1737

1984

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Acylation of the 4,5- and 5,6-double bond isomers of 3-steroidal thiazolidines: The chemical stability of spiro-3-steroidal 4,5- and 5,6-double bond isomers

Tetrahedron, 1981, Vol.37 (20), p.3463-3466

1981

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N,N′-Dialkylaminoalkylcarbonyl (DAAC) prodrugs and aminoalkylcarbonyl (AAC) prodrugs of 4-hydroxyacetanilide and naltrexone with improved skin permeation properties

A correlation of flux through a silicone membrane with flux through hairless mouse skin and human skin in vitro

Synthesis and topical delivery of N-alkyl- N-alkyloxycarbonylaminomethyl prodrugs of a model phenolic drug: Acetaminophen

Topical delivery of N-alkyl- N-alkyloxycarbonylaminomethyl (NANAOCAM) prodrugs of theophylline (ThH)

Synthesis of soft alkyl phenolic ether prodrugs using Mitsunobu chemistry

A comparison of the fit of flux through hairless mouse skin from water data to three model equations

α-(1 H-Imidazol-1-yl)alkyl (IMIDA) carboxylic acid esters as prodrugs of carboxylic acid containing drugs

Phenytoin Prodrugs III: Water-Soluble Prodrugs for Oral and/or Parenteral Use

Prodrugs of 6-Thiopurines: Enhanced Delivery Through the Skin

Transdermal delivery of theophylline from alcohol vehicles

Alcohol flux and effect on the delivery of theophylline from propylene glycol

Degradation of aspartame in acidic aqueous media and its stabilization by complexation with cyclodextrins or modified cyclodextrins

Transdermal delivery of 5-fluorouracil (5-FU) through hairless mouse skin by 1-alkylaminocarbonyl-5-FU prodrugs: Physicochemical characterization of prodrugs and correlations with transdermal delivery

The estimation of relative water solubility for prodrugs that are unstable in water

Microcalorimetric study of the interactions of aspartame with β-cyclodextrin and hydroxypropyl-β-cyclodextrin: The anamalous heat of dilution of the latter

Hydroxymethyl and acyloxymethyl prodrugs of theophylline: enhanced delivery of polar drugs through skin

Improved delivery through biological membranes. XII. The effect of the incorporation of biphasic solubilizing groups into prodrugs of steroids

The effect of aminomethyl (N-Mannich base) derivatization on the ability of S 6-pivaloyloxymethyl-6-mercaptopurine prodrug to deliver 6-mercaptopurine through hairless mouse skin

The effect of aminomethyl(N-Manich base) derivatization on the ability of S6-pivaloyloxymethyl-6-mercaptopurine prodrug to deliver 6-mercaptopurine through hairless mouse skin

Mannich base derivatives of theophylline and 5-fluorouracil: syntheses, properties and topical delivery characteristics

13C NMR spectroscopy of 4,5- and 5,6-double bond isomers of spiro-3-steroidal ketone derivatives

13C NMR spectroscopy of 4,5- and 5,6-double bond isomers of spiro-3-steroidal ketone derivatives : The determination of the structures of steroidal thiazolidines

Acylation of the 4,5- and 5,6-double bond isomers of 3-steroidal thiazolidines

Acyloxyamines as Prodrugs of Anti-inflammatory Carboxylic Acids for Improved Delivery Through Skin

Acylation of the 4,5- and 5,6-double bond isomers of 3-steroidal thiazolidines: The chemical stability of spiro-3-steroidal 4,5- and 5,6-double bond isomers

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