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Reversal of a cholinergic-induced deficit in a rodent model of recognition memory by the selective 5-HT6 receptor antagonist, Ro 04-6790

Psychopharmacologia, 2003-12, Vol.170 (4), p.358-367

2003

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Characterization of Ro 04‐6790 and Ro 63‐0563: potent and selective antagonists at human and rat 5‐HT6 receptors

British journal of pharmacology, 1998-06, Vol.124 (3), p.556-562

1998

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5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential

The Journal of pharmacology and experimental therapeutics, 1998-08, Vol.286 (2), p.913

1998

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Prolonged sedation due to accumulation of conjugated metabolites of midazolam

The Lancet (British edition), 1995-07, Vol.346 (8968), p.145-147

1995

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Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonists

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (5), p.1362-1365

2006

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Involvement of 5‐HT6 receptors in nigro‐striatal function in rodents

British journal of pharmacology, 1998-12, Vol.125 (7), p.1562-1566

1998

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Investigation of stretching behaviour induced by the selective 5‐HT6 receptor antagonist, Ro 04–6790, in rats

British journal of pharmacology, 1999-04, Vol.126 (7), p.1537-1542

1999

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5-HT6 receptor antagonists: lead optimisation and biological evaluation of N-aryl and N-heteroaryl 4-amino-benzene sulfonamides

European journal of medicinal chemistry, 2001-02, Vol.36 (2), p.165-178

2001

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Parallel solution- and solid-phase synthesis of spiropyrrolo-Pyrroles as novel neurokinin receptor ligands

Bioorganic & medicinal chemistry letters, 2002-11, Vol.12 (21), p.3073-3076

2002

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Effects of the 5-HT1D receptor antagonist GR127935 on extracellular levels of 5-HT in the guinea-pig frontal cortex as measured by microdialysis

Neuropharmacology, 1995-04, Vol.34 (4), p.377-382

1995

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Parallel solution- and solid-Phase synthesis of spirohydantoin derivatives as neurokinin-1 receptor ligands

Bioorganic & medicinal chemistry letters, 2002-09, Vol.12 (18), p.2519-2522

2002

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Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells

Neuropharmacology, 1997-04, Vol.36 (4-5), p.713-720

1997

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Identification of Residues in Transmembrane Regions III and VI that Contribute to the Ligand Binding Site of the Serotonin 5‐HT6 Receptor

Journal of neurochemistry, 1998-11, Vol.71 (5), p.2169-2177

1998

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Correlation between 5-HT7 receptor affinity and protection against sound-induced seizures in DBA/2J mice

Naunyn-Schmiedeberg's archives of pharmacology, 1997-12, Vol.356 (6), p.820-826

1997

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Radiolabelling of the human 5-HT2A receptor with an agonist, a partial agonist and an antagonist : effects of apparent agonist affinities

Biochemical pharmacology, 1996-01, Vol.51 (1), p.71-76

1996

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Influence of Median or Dorsal Raphe 5, 7-DHT Lesions on 5-ht6 Receptor Antagonist Activity in a Novel Object Discrimination Paradigm

Journal of Pharmacological Sciences, 2006, Vol.101 (suppl), p.125-125

2006

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O-Methylasparvenone, a nitrogen-free serotonin antagonist

Bioorganic & medicinal chemistry, 1997-12, Vol.5 (12), p.2165-2171

1997

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Pharmacologic evaluation of the discriminative stimulus of metachlorophenylpiperazine

Pharmacology, biochemistry and behavior, 1996, Vol.53 (1), p.107-114

1996

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Biphasic displacement of [ 3H]YM-09151-2 binding in the rat brain by thioridazine, risperidone and clozapine, but not by other antipsychotics

European journal of pharmacology, 1993-06, Vol.237 (2), p.183-189

1993

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Serotonin Receptor "Families" in the Central Nervous System: An Overview

Annals of the New York Academy of Sciences, 1990-01, Vol.600 (1), p.104-112

1990

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Syntheses of O-Methylasparvenone-Derived Serotonin-Receptor Antagonists

Helvetica chimica acta, 1998, Vol.81 (3-4), p.525-538

1998

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Relationship between extracellular 5‐hydroxytryptamine and behaviour following monoamine oxidase inhibition and l‐tryptophan

British journal of pharmacology, 1988-02, Vol.93 (2), p.303-310

1988

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Characterization of a novel and potent 5-hydroxytryptamine1A receptor antagonist

Pharmacology, biochemistry and behavior, 1991-03, Vol.38 (3), p.555-559

1991

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Synthesis, pharmacology and therapeutic potential of 10-methoxypyrazino[1,2- a]indoles, partial agonists at the 5HT 2C receptor

European journal of medicinal chemistry, 1997, Vol.32 (3), p.253-261

1997

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Identification of 5-hydroxytryptamine 1A receptor agents using a composite pharmacophore analysis and chemical database screening

Naunyn-Schmiedeberg's archives of pharmacology, 1991-02, Vol.343 (2), p.109-116

1991

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Reversal of a cholinergic-induced deficit in a rodent model of recognition memory by the selective 5-HT6 receptor antagonist, Ro 04-6790

Characterization of Ro 04‐6790 and Ro 63‐0563: potent and selective antagonists at human and rat 5‐HT6 receptors

5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential

Prolonged sedation due to accumulation of conjugated metabolites of midazolam

Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonists

Involvement of 5‐HT6 receptors in nigro‐striatal function in rodents

Investigation of stretching behaviour induced by the selective 5‐HT6 receptor antagonist, Ro 04–6790, in rats

5-HT6 receptor antagonists: lead optimisation and biological evaluation of N-aryl and N-heteroaryl 4-amino-benzene sulfonamides

Parallel solution- and solid-phase synthesis of spiropyrrolo-Pyrroles as novel neurokinin receptor ligands

Effects of the 5-HT1D receptor antagonist GR127935 on extracellular levels of 5-HT in the guinea-pig frontal cortex as measured by microdialysis

Parallel solution- and solid-Phase synthesis of spirohydantoin derivatives as neurokinin-1 receptor ligands

Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells

Identification of Residues in Transmembrane Regions III and VI that Contribute to the Ligand Binding Site of the Serotonin 5‐HT6 Receptor

Correlation between 5-HT7 receptor affinity and protection against sound-induced seizures in DBA/2J mice

Radiolabelling of the human 5-HT2A receptor with an agonist, a partial agonist and an antagonist : effects of apparent agonist affinities

Influence of Median or Dorsal Raphe 5, 7-DHT Lesions on 5-ht6 Receptor Antagonist Activity in a Novel Object Discrimination Paradigm

O-Methylasparvenone, a nitrogen-free serotonin antagonist

Pharmacologic evaluation of the discriminative stimulus of metachlorophenylpiperazine

Biphasic displacement of [ 3H]YM-09151-2 binding in the rat brain by thioridazine, risperidone and clozapine, but not by other antipsychotics

Serotonin Receptor "Families" in the Central Nervous System: An Overview

Syntheses of O-Methylasparvenone-Derived Serotonin-Receptor Antagonists

Relationship between extracellular 5‐hydroxytryptamine and behaviour following monoamine oxidase inhibition and l‐tryptophan

Characterization of a novel and potent 5-hydroxytryptamine1A receptor antagonist

Synthesis, pharmacology and therapeutic potential of 10-methoxypyrazino[1,2- a]indoles, partial agonists at the 5HT 2C receptor

Identification of 5-hydroxytryptamine 1A receptor agents using a composite pharmacophore analysis and chemical database screening

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