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Role of HBx in hepatitis B virus persistence and its therapeutic implications

Current opinion in virology, 2018-06, Vol.30, p.32-38

2018

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Hepatitis B Virus X and Regulation of Viral Gene Expression

Cold Spring Harbor perspectives in medicine, 2016-03, Vol.6 (3), p.a021402-a021402

2016

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Hepatitis B Virus Regulatory HBx Protein Binds to Adaptor Protein IPS-1 and Inhibits the Activation of Beta Interferon

Journal of Virology, 2011-01, Vol.85 (2), p.987-995

2011

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Technical standards for hepatitis B virus X protein (HBx) research

Hepatology (Baltimore, Md.), 2015-04, Vol.61 (4), p.1416-1424

2015

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Hepatitis B virus HBx protein interactions with the ubiquitin proteasome system

Viruses, 2014-11, Vol.6 (11), p.4683-4702

2014

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Activation of signal transduction pathways during hepatic oncogenesis

Cancer letters, 2016-01, Vol.370 (1), p.1-9

2016

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Elevated Expression of the miR-17–92 Polycistron and miR-21 in Hepadnavirus-Associated Hepatocellular Carcinoma Contributes to the Malignant Phenotype

The American journal of pathology, 2008-09, Vol.173 (3), p.856-864

2008

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Enhancement of Hepatitis B Virus Replication by the Regulatory X Protein In Vitro and In Vivo

Journal of Virology, 2007-03, Vol.81 (6), p.2656-2662

2007

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Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex

Cells (Basel, Switzerland), 2020-03, Vol.9 (4), p.834

2020

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Overexpression of insulin receptor substrate‐1 and hepatitis Bx genes causes premalignant alterations in the liver

Hepatology (Baltimore, Md.), 2009-06, Vol.49 (6), p.1935-1943

2009

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Hepatitis B virus HBx protein localized to the nucleus restores HBx-deficient virus replication in HepG2 cells and in vivo in hydrodynamically-injected mice

Virology (New York, N.Y.), 2009-07, Vol.390 (1), p.122-129

2009

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A hepatitis B virus transgenic mouse model with a conditional, recombinant, episomal genome

JHEP reports, 2021-04, Vol.3 (2), p.100252-100252, Article 100252

2021

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Relative Abundance of Integrant-Derived Viral RNAs in Infected Tissues Harvested from Chronic Hepatitis B Virus Carriers

Journal of virology, 2018-05, Vol.92 (10)

2018

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Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

Nature genetics, 2014-12, Vol.46 (12), p.1267-1273

2014

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Farnesoid X receptor ablation sensitizes mice to hepatitis b virus X protein–induced hepatocarcinogenesis

Hepatology (Baltimore, Md.), 2017-03, Vol.65 (3), p.893-906

2017

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Enhancement of Hepatitis B Virus Replication by Its X Protein in Transgenic Mice

Journal of Virology, 2002-03, Vol.76 (5), p.2579-2584

2002

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Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication

Virology (New York, N.Y.), 2012-04, Vol.426 (1), p.73-82

2012

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Altered DNA Mutation Spectrum in Aflatoxin B1-Treated Transgenic Mice That Express the Hepatitis B Virus X Protein

Journal of Virology, 2002-11, Vol.76 (22), p.11770-11774

2002

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Premature Cell Cycle Entry Induced by Hepatitis B Virus Regulatory HBx Protein during Compensatory Liver Regeneration

Cancer research (Chicago, Ill.), 2008-12, Vol.68 (24), p.10341-10348

2008

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The C-terminal region of the hepatitis B virus X protein is required for its stimulation of HBV replication in primary mouse hepatocytes

Virus research, 2012-05, Vol.165 (2), p.170-178

2012

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BRIT1 dysfunction confers synergistic inhibition of hepatocellular carcinoma by targeting poly (ADP-ribose) polymerases and PI3K

American journal of cancer research, 2020-01, Vol.10 (6), p.1900-1918

2020

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Hepatitis B Virus X Protein Acts as a Tumor Promoter in Development of Diethylnitrosamine-Induced Preneoplastic Lesions

Journal of Virology, 2001-04, Vol.75 (8), p.3851-3858

2001

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Hepatitis B Virus X Protein Interferes with Cellular DNA Repair

Journal of Virology, 1998-01, Vol.72 (1), p.266-272

1998

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Nature (London), 1992-03, Vol.356 (6366), p.215-221

1992

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Increased liver pathology in hepatitis C virus transgenic mice expressing the hepatitis B virus X protein

Virology (New York, N.Y.), 2006-04, Vol.347 (2), p.466-475

2006

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Role of HBx in hepatitis B virus persistence and its therapeutic implications

Hepatitis B Virus X and Regulation of Viral Gene Expression

Hepatitis B Virus Regulatory HBx Protein Binds to Adaptor Protein IPS-1 and Inhibits the Activation of Beta Interferon

Technical standards for hepatitis B virus X protein (HBx) research

Hepatitis B virus HBx protein interactions with the ubiquitin proteasome system

Activation of signal transduction pathways during hepatic oncogenesis

Elevated Expression of the miR-17–92 Polycistron and miR-21 in Hepadnavirus-Associated Hepatocellular Carcinoma Contributes to the Malignant Phenotype

Enhancement of Hepatitis B Virus Replication by the Regulatory X Protein In Vitro and In Vivo

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex

Overexpression of insulin receptor substrate‐1 and hepatitis Bx genes causes premalignant alterations in the liver

Hepatitis B virus HBx protein localized to the nucleus restores HBx-deficient virus replication in HepG2 cells and in vivo in hydrodynamically-injected mice

A hepatitis B virus transgenic mouse model with a conditional, recombinant, episomal genome

Relative Abundance of Integrant-Derived Viral RNAs in Infected Tissues Harvested from Chronic Hepatitis B Virus Carriers

Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

Farnesoid X receptor ablation sensitizes mice to hepatitis b virus X protein–induced hepatocarcinogenesis

Enhancement of Hepatitis B Virus Replication by Its X Protein in Transgenic Mice

Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication

Altered DNA Mutation Spectrum in Aflatoxin B1-Treated Transgenic Mice That Express the Hepatitis B Virus X Protein

Premature Cell Cycle Entry Induced by Hepatitis B Virus Regulatory HBx Protein during Compensatory Liver Regeneration

The C-terminal region of the hepatitis B virus X protein is required for its stimulation of HBV replication in primary mouse hepatocytes

BRIT1 dysfunction confers synergistic inhibition of hepatocellular carcinoma by targeting poly (ADP-ribose) polymerases and PI3K

Hepatitis B Virus X Protein Acts as a Tumor Promoter in Development of Diethylnitrosamine-Induced Preneoplastic Lesions

Hepatitis B Virus X Protein Interferes with Cellular DNA Repair

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Increased liver pathology in hepatitis C virus transgenic mice expressing the hepatitis B virus X protein

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