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Brønsted Acid-Catalyzed Highly Stereoselective Arene-Ynamide Cyclizations. A Novel Keteniminium Pictet−Spengler Cyclization in Total Syntheses of (±)-Desbromoarborescidines A and C

Organic letters, 2005-03, Vol.7 (6), p.1047-1050

2005

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Multiparameter Optimization of Trypanocidal Cruzain Inhibitors With In Vivo Activity and Favorable Pharmacokinetics

Frontiers in pharmacology, 2022-01, Vol.12, p.774069-774069

2022

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Synthesis and Anti-Trypanosoma cruzi Activity of 3‑Cyanopyridine Derivatives

ACS omega, 2024-05, Vol.9 (20), p.22360-22370

2024

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Fully Substituted Carbon Centers by Diastereoselective Spirocyclization: Stereoselective Synthesis of (+)-Lepadiformine C

Journal of the American Chemical Society, 2010-07, Vol.132 (28), p.9591-9593

2010

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ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment

Molecular cancer therapeutics, 2018-06, Vol.17 (6), p.1156-1166

2018

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Asymmetric Carbon−Carbon Bond Formations in Conjugate Additions of Lithiated N-Boc Allylic and Benzylic Amines to Nitroalkenes: Enantioselective Synthesis of Substituted Piperidines, Pyrrolidines, and Pyrimidinones

Journal of the American Chemical Society, 2002-10, Vol.124 (39), p.11689-11698

2002

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Discovery of Potent, Reversible, and Competitive Cruzain Inhibitors with Trypanocidal Activity: A Structure-Based Drug Design Approach

Journal of chemical information and modeling, 2020-02, Vol.60 (2), p.1028-1041

2020

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Total Synthesis of Lepadiformine Alkaloids using N-Boc α-Amino Nitriles as Trianion Synthons

Journal of organic chemistry, 2012-04, Vol.77 (7), p.3390-3400

2012

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Molecular modeling and structure-activity relationships for a series of benzimidazole derivatives as cruzain inhibitors

Future medicinal chemistry, 2017-05, Vol.9 (7), p.641-657

2017

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Total Synthesis of (+)-Lepadin F

Organic letters, 2008-11, Vol.10 (21), p.4991-4994

2008

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Total Synthesis of Lepadiformine Alkaloids using N-Boc α-Amino Nitriles as Trianion Synthonsa

Journal of organic chemistry, 2012-03, Vol.77 (7), p.3390-3400

2012

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Stereodivergent Approach to Both C2,8a-syn and C2,8a-anti Relative Stereochemical Manifolds in the Lepadin Family via a TiCl4-Promoted Aza-[3+3] Annulation

Synthesis (Stuttgart), 2009-09, Vol.2009 (17), p.2905-2914

2009

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A reductive cyclization approach to (−)-histrionicotoxin 235A and lepadiformine B

Slafer, Brian W

2009

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ChemInform Abstract: Total Synthesis of (+)-Lepadin F

ChemInform, 2009-03, Vol.40 (12), p.no-no

2009

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Broensted Acid Catalyzed Highly Stereoselective Arene-Ynamide Cyclizations. A Novel Keteniminium Pictet-Spengler Cyclization in Total Syntheses of (.+-.)-Desbromoarborescidines A and C

ChemInform, 2005-08, Vol.36 (32), p.no-no

2005

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Asymmetric Carbon-Carbon Bond Formations in Conjugate Additions of Lithiated N-Boc Allylic and Benzylic Amines to Nitroalkenes: Enantioselective Synthesis of Substituted Piperidines, Pyrrolidines, and Pyrimidinones

ChemInform, 2003-02, Vol.34 (6), p.no-no

2003

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Carbamoyl Imidazoles As Potent, Reversible and Competitive Cruzain Inhibitors with in vitro and in vivo Trypanocidal Activity: A Structure-Based Drug Design Approach

SSRN Electronic Journal

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Brønsted Acid-Catalyzed Highly Stereoselective Arene-Ynamide Cyclizations. A Novel Keteniminium Pictet−Spengler Cyclization in Total Syntheses of (±)-Desbromoarborescidines A and C

Multiparameter Optimization of Trypanocidal Cruzain Inhibitors With In Vivo Activity and Favorable Pharmacokinetics

Synthesis and Anti-Trypanosoma cruzi Activity of 3‑Cyanopyridine Derivatives

Fully Substituted Carbon Centers by Diastereoselective Spirocyclization: Stereoselective Synthesis of (+)-Lepadiformine C

ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment

Asymmetric Carbon−Carbon Bond Formations in Conjugate Additions of Lithiated N-Boc Allylic and Benzylic Amines to Nitroalkenes: Enantioselective Synthesis of Substituted Piperidines, Pyrrolidines, and Pyrimidinones

Discovery of Potent, Reversible, and Competitive Cruzain Inhibitors with Trypanocidal Activity: A Structure-Based Drug Design Approach

Total Synthesis of Lepadiformine Alkaloids using N-Boc α-Amino Nitriles as Trianion Synthons

Molecular modeling and structure-activity relationships for a series of benzimidazole derivatives as cruzain inhibitors

Total Synthesis of (+)-Lepadin F

Total Synthesis of Lepadiformine Alkaloids using N-Boc α-Amino Nitriles as Trianion Synthonsa

Stereodivergent Approach to Both C2,8a-syn and C2,8a-anti Relative Stereochemical Manifolds in the Lepadin Family via a TiCl4-Promoted Aza-[3+3] Annulation

A reductive cyclization approach to (−)-histrionicotoxin 235A and lepadiformine B

ChemInform Abstract: Total Synthesis of (+)-Lepadin F

Broensted Acid Catalyzed Highly Stereoselective Arene-Ynamide Cyclizations. A Novel Keteniminium Pictet-Spengler Cyclization in Total Syntheses of (.+-.)-Desbromoarborescidines A and C

Asymmetric Carbon-Carbon Bond Formations in Conjugate Additions of Lithiated N-Boc Allylic and Benzylic Amines to Nitroalkenes: Enantioselective Synthesis of Substituted Piperidines, Pyrrolidines, and Pyrimidinones

Carbamoyl Imidazoles As Potent, Reversible and Competitive Cruzain Inhibitors with in vitro and in vivo Trypanocidal Activity: A Structure-Based Drug Design Approach

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