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Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development

Angewandte Chemie (International ed.), 2006-12, Vol.45 (47), p.7942-7948

2006

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Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Cancer research (Chicago, Ill.), 2008-07, Vol.68 (13), p.5301-5308

2008

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Discovery of quinolines as selective glucocorticoid receptor agonists

Bioorganic & medicinal chemistry letters, 2010-10, Vol.20 (19), p.5835-5838

2010

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Efficient Chiral Pool Synthesis of the C1-C6 Fragment of Epothilones

Synthesis (Stuttgart), 2005, Vol.2005 (2), p.301-305

2005

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Novel 3-Oxa Lipoxin A4 Analogues with Enhanced Chemical and Metabolic Stability Have Anti-inflammatory Activity in Vivo

Journal of medicinal chemistry, 2004-04, Vol.47 (8), p.2157-2165

2004

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SAGOPILONE, A NOVEL EPOTHILONE, INHIBITS TUMOR CELL GROWTH IN PRECLINICAL MODELS OF UROLOGICAL CANCER

The Journal of urology, 2008, Vol.179 (4), p.479-479

2008

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Efficient Chiral Pool Synthesis of the C1-C6 Fragment of Epothilones

Synthesis (Stuttgart), 2005-02, Vol.2005 (2), p.301-305

2005

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Cover Picture: Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development (Angew. Chem. Int. Ed. 47/2006)

Angewandte Chemie (International ed.), 2006-12, Vol.45 (47), p.7855-7855

2006

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Moderate Correlations of in vitro versus in vivo Pharmacokinetics Questioning the Need of Early Microsomal Stability Testing

Pharmacology, 2012-01, Vol.90 (5-6), p.307-315

2012

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Novel macrocyclic templates by ring enlargement of ansa-steroids

Tetrahedron letters, 2004-12, Vol.45 (52), p.9569-9571

2004

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Total Synthesis and Antitumor Activity of ZK‐EPO: The First Fully Synthetic Epothilone in Clinical Development

Angewandte Chemie, 2006-12, Vol.118 (47), p.8110-8116

2006

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Titelbild: Total Synthesis and Antitumor Activity of ZK‐EPO: The First Fully Synthetic Epothilone in Clinical Development (Angew. Chem. 47/2006)

Angewandte Chemie, 2006-12, Vol.118 (47), p.8019-8019

2006

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The identification of a small molecule inhibitor that specifically reduces T cell-mediated adaptive but not LPS-mediated innate immunity by T cell membrane–monocyte contact bioassay

Immunology letters, 2008-04, Vol.117 (1), p.114-118

2008

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Design and synthesis of macrocyclic inhibitors of phosphatase Cdc25B

Bioorganic & medicinal chemistry letters, 2004-04, Vol.14 (7), p.1673-1677

2004

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From Rigidity to Conformational Flexibility: Macrocyclic Templates Derived from ansa-Steroids

Angewandte Chemie (International ed.), 2003-08, Vol.42 (33), p.3961-3964

2003

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Novel 3-Oxa Lipoxin A 4 Analogues with Enhanced Chemical and Metabolic Stability Have Anti-inflammatory Activity in Vivo

Journal of medicinal chemistry, 2004-04, Vol.47 (8), p.2157-2165

2004

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Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development

Angewandte Chemie, 2006-12, Vol.118 (47), p.8110-8116

2006

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Titelbild: Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development (Angew. Chem. 47/2006)

Angewandte Chemie, 2006-12, Vol.118 (47), p.8019-8019

2006

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Von Rigidität zu konformativer Flexibilität: makrocyclische Template, abgeleitet von Ansa-Steroiden

Angewandte Chemie, 2003-08, Vol.115 (33), p.4091-4094

2003

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Notiz über die Umwandlung von Allylalkoholen in Kohlenwasserstoffe

Chemische Berichte, 1976-04, Vol.109 (4), p.1586-1588

1976

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Synthesis of 6,9-homo-prostacyclin a stable prostacyclin analog

Tetrahedron letters, 1980, Vol.21 (34), p.3261-3264

Skuballa, Werner

1980

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Mikrobiologische und Enzymatische Reaktionsstufen in der Synthese von Prostacyclin-Analoga

Liebigs Annalen der Chemie, 1990-11, Vol.1990 (11), p.1087-1091

1990

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Ein neuer Weg zu 6a-Carbacyclinen - Synthese eines stabilen, biologisch potenten Prostacyclin-Analogons

Angewandte Chemie, 1981-12, Vol.93 (12), p.1080-1081

1981

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A New Route to 6a-Carbacyclins-Synthesis of a Stable, Biologically Potent Prostacyclin Analogue

Angewandte Chemie (International ed.), 1981-12, Vol.20 (12), p.1046-1048

1981

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Von Rigidität zu konformativer Flexibilität: makrocyclische Template, abgeleitet von Ansa‐Steroiden

Angewandte Chemie, 2003-08, Vol.115 (33), p.4091-4094

2003

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Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development

Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Discovery of quinolines as selective glucocorticoid receptor agonists

Efficient Chiral Pool Synthesis of the C1-C6 Fragment of Epothilones

Novel 3-Oxa Lipoxin A4 Analogues with Enhanced Chemical and Metabolic Stability Have Anti-inflammatory Activity in Vivo

SAGOPILONE, A NOVEL EPOTHILONE, INHIBITS TUMOR CELL GROWTH IN PRECLINICAL MODELS OF UROLOGICAL CANCER

Efficient Chiral Pool Synthesis of the C1-C6 Fragment of Epothilones

Cover Picture: Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development (Angew. Chem. Int. Ed. 47/2006)

Moderate Correlations of in vitro versus in vivo Pharmacokinetics Questioning the Need of Early Microsomal Stability Testing

Novel macrocyclic templates by ring enlargement of ansa-steroids

Total Synthesis and Antitumor Activity of ZK‐EPO: The First Fully Synthetic Epothilone in Clinical Development

Titelbild: Total Synthesis and Antitumor Activity of ZK‐EPO: The First Fully Synthetic Epothilone in Clinical Development (Angew. Chem. 47/2006)

The identification of a small molecule inhibitor that specifically reduces T cell-mediated adaptive but not LPS-mediated innate immunity by T cell membrane–monocyte contact bioassay

Design and synthesis of macrocyclic inhibitors of phosphatase Cdc25B

From Rigidity to Conformational Flexibility: Macrocyclic Templates Derived from ansa-Steroids

Novel 3-Oxa Lipoxin A 4 Analogues with Enhanced Chemical and Metabolic Stability Have Anti-inflammatory Activity in Vivo

Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development

Titelbild: Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development (Angew. Chem. 47/2006)

Von Rigidität zu konformativer Flexibilität: makrocyclische Template, abgeleitet von Ansa-Steroiden

Notiz über die Umwandlung von Allylalkoholen in Kohlenwasserstoffe

Synthesis of 6,9-homo-prostacyclin a stable prostacyclin analog

Mikrobiologische und Enzymatische Reaktionsstufen in der Synthese von Prostacyclin-Analoga

Ein neuer Weg zu 6a-Carbacyclinen - Synthese eines stabilen, biologisch potenten Prostacyclin-Analogons

A New Route to 6a-Carbacyclins-Synthesis of a Stable, Biologically Potent Prostacyclin Analogue

Von Rigidität zu konformativer Flexibilität: makrocyclische Template, abgeleitet von Ansa‐Steroiden

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