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Mutagenicity of butadiene and its epoxide metabolites: I. Mutagenic potential of 1,2-epoxybutene, 1,2,3,4-diepoxybutane and 3,4-epoxy-1,2-butanediol in cultured human lymphoblasts

Carcinogenesis (New York), 1994-04, Vol.15 (4), p.713-717

1994

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Mutagenicity of butadiene and its epoxide metabolites: II. Mutational spectra of butadiene, 1,2-epoxybutene and diepoxybutane at the hprt locus in splenic T cells from exposed B6C3F1 mice

Carcinogenesis (New York), 1994-04, Vol.15 (4), p.719-723

1994

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Computer program for the analysis of mutational spectra: application to p53 mutations

Carcinogenesis (New York), 1994-10, Vol.15 (10), p.2281-2285

1994

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In vivo transgenic mutation assays

Environmental and molecular mutagenesis, 2000, Vol.35 (3), p.253-259

2000

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Mutational spectrum at the Hprt locus in splenic T cells of B6C3F1 mice exposed to N-ethyl-N-nitrosourea

Proceedings of the National Academy of Sciences - PNAS, 1992-09, Vol.89 (17), p.7866-7870

1992

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Suppression of spontaneous and hydrogen peroxide-induced mutagenesis by the antioxidant ascorbate in mismatch repair-deficient human colon cancer cells

Carcinogenesis (New York), 2001-10, Vol.22 (10), p.1709-1713

2001

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Frequency and spectrum of ethylnitrosourea-induced mutation at the hprt and lacI loci in splenic lymphocytes of exposed lacI transgenic mice

Cancer research (Chicago, Ill.), 1996-10, Vol.56 (20), p.4654-4661

1996

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Specificity of mutations induced by the food-associated heterocyclic amine 2-amino-1-methyl-6-phenylimidazo-[4,5-b]-pyridine in colon cancer cell lines defective in mismatch repair

Cancer research (Chicago, Ill.), 2000-09, Vol.60 (17), p.4921-4925

2000

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Analysis of Mutations Occurring at the Human hprt Locus

Journal of molecular biology, 1993-05, Vol.231 (1), p.41-57

1993

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DNA Base Changes and Alkylation Following in vivo Exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea

Proceedings of the National Academy of Sciences - PNAS, 1987, Vol.84 (2), p.344-348

1987

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Statistical test for the comparison of samples from mutational spectra

Journal of molecular biology, 1987-04, Vol.194 (3), p.391-396

1987

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Cytotoxic and mutagenic response of mismatch repair-defective human cancer cells exposed to a food-associated heterocyclic amine

Carcinogenesis (New York), 1999-03, Vol.20 (3), p.391-394

1999

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Transgenic mutation models: Research, testing, and reality checks

Environmental and molecular mutagenesis, 1998, Vol.32 (2), p.104-105

Skopek, Thomas R.

1998

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Molecular dosimetry of ethylene oxide : formation and persistence of 7-(2-hydroxyethyl)guanine in DNA following repeated exposures of rats and mice

Cancer research (Chicago, Ill.), 1992-08, Vol.52 (16), p.4328-4334

1992

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Fidelity of Thermococcus litoralis DNA polymerase (VentTM) in PCR determined by denaturing gradient gel electrophoresis

Nucleic acids research, 1991-08, Vol.19 (15), p.4193-4198

1991

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Culture and propagation of Hprt mutant T-lymphocytes isolated from mouse spleen

Environmental and molecular mutagenesis, 1998, Vol.32 (3), p.236-243

1998

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Mutagenicity of vinyl chloride and its reactive metabolites, chloroethylene oxide and chloroacetaldehyde, in a metabolically competent human B-lymphoblastoid line

Carcinogenesis (New York), 1997, Vol.18 (1), p.31-36

1997

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Comparison of motility and membrane integrity to assess rat sperm viability

Reproductive toxicology (Elmsford, N.Y.), 1998-03, Vol.12 (2), p.105-114

1998

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A method for specific cloning and sequencing of human hprt cDNA for mutation analysis

Biochemical and biophysical research communications, 1988-02, Vol.151 (1), p.487-492

1988

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High Frequency of Large Spontaneous Deletions of DNA in Tumor-Derived CHEF Cells

Proceedings of the National Academy of Sciences - PNAS, 1989-04, Vol.86 (7), p.2306-2310

1989

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Biomarkers of exposure and effect as indicators of potential carcinogenic risk arising from in vivo metabolism of ethylene to ethylene oxide

Carcinogenesis (New York), 2000-09, Vol.21 (9), p.1661-1669

2000

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Changes in DNA base sequence induced by targeted mutagenesis of lambda phage by ultraviolet light

Journal of molecular biology, 1984-03, Vol.173 (3), p.273-291

1984

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The effects of hypoxia and cysteamine on X-ray mutagenesis in human cells. II. hprt mRNA expression and cDNA sequence analysis of induced mutants

Radiation research, 1993-11, Vol.136 (2), p.271

1993

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Extent of CpG methylation is not proportional to the in vivo spontaneous mutation frequency at transgenic loci in Big Blue™ rodents

Mutation research, 2001-05, Vol.476 (1), p.1-11

2001

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Mutational spectrum of ICR-191 at the hprt locus in human lymphoblastoid cells

Environmental and molecular mutagenesis, 1994, Vol.23 (2), p.96-100

1994

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Mutagenicity of butadiene and its epoxide metabolites: I. Mutagenic potential of 1,2-epoxybutene, 1,2,3,4-diepoxybutane and 3,4-epoxy-1,2-butanediol in cultured human lymphoblasts

Mutagenicity of butadiene and its epoxide metabolites: II. Mutational spectra of butadiene, 1,2-epoxybutene and diepoxybutane at the hprt locus in splenic T cells from exposed B6C3F1 mice

Computer program for the analysis of mutational spectra: application to p53 mutations

In vivo transgenic mutation assays

Mutational spectrum at the Hprt locus in splenic T cells of B6C3F1 mice exposed to N-ethyl-N-nitrosourea

Suppression of spontaneous and hydrogen peroxide-induced mutagenesis by the antioxidant ascorbate in mismatch repair-deficient human colon cancer cells

Frequency and spectrum of ethylnitrosourea-induced mutation at the hprt and lacI loci in splenic lymphocytes of exposed lacI transgenic mice

Specificity of mutations induced by the food-associated heterocyclic amine 2-amino-1-methyl-6-phenylimidazo-[4,5-b]-pyridine in colon cancer cell lines defective in mismatch repair

Analysis of Mutations Occurring at the Human hprt Locus

DNA Base Changes and Alkylation Following in vivo Exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea

Statistical test for the comparison of samples from mutational spectra

Cytotoxic and mutagenic response of mismatch repair-defective human cancer cells exposed to a food-associated heterocyclic amine

Transgenic mutation models: Research, testing, and reality checks

Molecular dosimetry of ethylene oxide : formation and persistence of 7-(2-hydroxyethyl)guanine in DNA following repeated exposures of rats and mice

Fidelity of Thermococcus litoralis DNA polymerase (VentTM) in PCR determined by denaturing gradient gel electrophoresis

Culture and propagation of Hprt mutant T-lymphocytes isolated from mouse spleen

Mutagenicity of vinyl chloride and its reactive metabolites, chloroethylene oxide and chloroacetaldehyde, in a metabolically competent human B-lymphoblastoid line

Comparison of motility and membrane integrity to assess rat sperm viability

A method for specific cloning and sequencing of human hprt cDNA for mutation analysis

High Frequency of Large Spontaneous Deletions of DNA in Tumor-Derived CHEF Cells

Biomarkers of exposure and effect as indicators of potential carcinogenic risk arising from in vivo metabolism of ethylene to ethylene oxide

Changes in DNA base sequence induced by targeted mutagenesis of lambda phage by ultraviolet light

The effects of hypoxia and cysteamine on X-ray mutagenesis in human cells. II. hprt mRNA expression and cDNA sequence analysis of induced mutants

Extent of CpG methylation is not proportional to the in vivo spontaneous mutation frequency at transgenic loci in Big Blue™ rodents

Mutational spectrum of ICR-191 at the hprt locus in human lymphoblastoid cells

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